Abstract: The present invention provides biologically active compounds that bind an ?5?1 integrin. Also included in the present invention are methods for using such biologically active compounds.
Abstract: Miniature robotic vehicles suitable for a variety of tasks including covert surveillance, reconnaissance, and recreation are provided. Embodiments of the invention may include vehicles having a hybrid transportation system that incorporates a rotary-wing flight mode in conjunction with a wheeled ground transport mode. As a result, exemplary vehicles provide efficient ground-mode travel, with the added ability to fly over large obstacles and rough terrain.
Type:
Grant
Filed:
December 7, 2010
Date of Patent:
January 1, 2013
Assignee:
Regents of the University of Minnesota
Inventors:
Nikolaos P. Papanikolopoulos, Alex J. Kossett
Abstract: The present invention provides methods of killing, inhibiting the growth, and/or inhibiting the reproduction of kine-toplastid or apicomplexan protozoan with tyrosine kinase inhibitors.
Type:
Grant
Filed:
November 21, 2007
Date of Patent:
December 25, 2012
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: A magnetic sensor includes a reference layer having a first magnetization direction and a free layer assembly having an effective magnetization direction substantially perpendicular to the first magnetization direction and substantially perpendicular to a plane of each layer of the free layer assembly. A spacer layer is between the reference layer and the free layer, and a signal enhancement layer is exchange coupled to the free layer assembly on a side opposite the spacer layer.
Type:
Grant
Filed:
March 15, 2011
Date of Patent:
December 18, 2012
Assignee:
Seagate Technology LLC
Inventors:
Song S. Xue, Zheng Gao, Shaoping Li, Kaizhong Gao, Dimitar V. Dimitrov, Konstantin Nikolaev, Patrick J. Ryan
Abstract: Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.
Type:
Grant
Filed:
September 21, 2007
Date of Patent:
December 18, 2012
Assignees:
The Board of Regents, The University of Texas System, The Texas A&M University System
Inventors:
Darrell H. Carney, Barbara Olszewska-Pazdrak, Theresa W. Fossum
Abstract: A disc drive system provides increased reliability by detecting and correcting errors associated with bit-patterned media. Write synchronization errors associated with bit-patterned media are addressed by including data storage for temporarily storing data that is being written to the disc drive. The data is read from both the disc drive and the storage medium and compared to detect write synchronization errors. The disc drive system utilizes the identified write synchronization errors for at least one of timing recovery, equalizer training detection, error correction code application, and error recovery.
Type:
Grant
Filed:
October 14, 2010
Date of Patent:
December 11, 2012
Assignee:
Seagate Technology LLC
Inventors:
Michael L. Mallary, Mehmet F. Erden, Ching He, Venkata S. Chilaka
Abstract: The present invention provides isolated metal regulated polypeptides obtainable from a Campylobacter spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for treating in infection in a subject, for treating a condition caused by a Campylobacter spp., and for decreasing colonization of an animal.
Abstract: A sensitive, multicomponent diagnostic test for infection with T. cruzi, the causative agent of Chagas disease, including methods of making and methods of use. Also provided is a method for screening T. cruzi polypeptides to identify antigenic polypeptides for inclusion as components of the diagnostic test, as well as compositions containing antigenic T. cruzi polypeptides.
Type:
Grant
Filed:
July 30, 2008
Date of Patent:
December 11, 2012
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
Rick L. Tarleton, Ronald D. Etheridge, Jr.
Abstract: A memory comprising at least one memory cell operationally connected to a bit line, a source line and a word line. The memory cell comprises a substrate having a first source contact, a second source contact, and a bit contact between the first source contact and the second source contact, a first transistor gate electrically connecting the first source contact and the bit contact and a second transistor gate electrically connecting the bit contact and the second source contact. The word line electrically connects the first transistor gate to the second transistor gate.
Type:
Grant
Filed:
October 25, 2011
Date of Patent:
December 4, 2012
Assignee:
Seagate Technology LLC
Inventors:
Roger Glenn Rolbiecki, Andrew Carter, Yong Lu
Abstract: Isolated polypeptides, nucleic acids, and methods relating to cellular internalization of materials are described herein. Generally, the isolated polypeptides include a membrane transduction domain of human tissue factor pathway inhibitor-2 (TFPI-2). In some cases, the isolated polypeptide can be a fusion peptide that includes a membrane transduction domain of human TFPI-2 and a heterologous peptide domain. The nucleic acids include nucleic acids that encode the isolated polypeptides described herein. The methods generally include providing a composition that includes a membrane transduction domain of human TFPI-2 coupled to a material, and contacting the composition with a cell under conditions effective to permit the cell to internalize the composition.
Abstract: Nematic liquid crystal cells with positive dielectric anisotropy that include colloidal suspensions having nanoclusters (e.g., CdTe nanoclusters, CdSe nanoclusters) that include a pure monolayer of ligands are provided as well as methods of inducing Freedericksz transitions in the nematic liquid crystal cells and methods of controlling the alignment of a liquid crystal.
Abstract: Methods according to the invention administering one or more rice rhizosphere isolates to a plant, particularly a rice plant, to the seed of the plant, or to soil surrounding the plant in an amount effective to inhibit infection by a plant pathogen, particularly rice blast, to increase the biomass of the plant, and/or to decrease arsenic uptake by the plant.
Abstract: Nematic liquid crystal cells with positive dielectric anisotropy that include colloidal suspensions having nanoclusters are provided as well as methods of inducing Freedericksz transitions therein and methods of controlling the alignment of a liquid crystal.
Abstract: Apparatus and methods for internal surgical procedures are disclosed. The apparatus and methods may involve supporting internal body locations, creating submucosal separations (blebs), and/or for resecting mucosal tissue separated from underlying tissue by a bleb.
Type:
Grant
Filed:
May 11, 2006
Date of Patent:
October 16, 2012
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Jose G. de la Mora Levy, Christopher J. Gostout
Abstract: The present invention provides compositions including siderophore receptor polypeptides from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions.
Abstract: Fluid compositions and methods of making and using same are described, one composition comprising a well treatment fluid and an additive combined with the well treatment fluid, wherein the additive is selected from solids, liquids and combinations thereof, the additive having a surface shape, at least one property of the surface shape enabling it to change under influence of a controllable parameter after the composition is deployed into a hydraulic fracture or gravel pack. In methods of the disclosure, the additive exists initially in a first state, and then is changed to a second state. The first state may increase proppant flowback efficiency, while the second state may increase hydraulic conductivity. In certain embodiments, the additive may change back to its first state.
Abstract: A container incorporating an integral roller surface for use with a roller-type liquid applicator. The roller surface may be movable from a first, operational position to a second, access position. The floor of the container may be sloped so that a well forms at a particular location, e.g., at or near one end of the container. The roller surface preferably provides access to the well during use. When the roller surface is moved to the second, access position, the sloped floor of the container may provide a second roller surface.
Type:
Grant
Filed:
January 15, 2004
Date of Patent:
October 9, 2012
Assignee:
Valspar Sourcing, Inc.
Inventors:
James R. Robellard, Steven D. Person, Gary F. Prokop, Randall P. Bell, Mark D. Kiel, Allen B. McKittrick
Abstract: Microbial production of pyruvate and metabolites derived from pyruvate in cells exhibiting reduced pyruvate dehydrogenase activity compared to wild-type cells. Acetate and glucose are supplied as a carbon sources.
Type:
Grant
Filed:
June 28, 2010
Date of Patent:
October 2, 2012
Assignee:
University of Georgia Research Foundation, Inc.