Abstract: A dispenser is enclosed for delivering a beneficial agent to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising carrier means for housing a beneficial agent, push means for pushing the carrier means from the dispenser and fragmenting means for fragmenting the carrier means as it is pushed from the dispenser.

Abstract: A delivery system is disclosed for delivering a beneficial agent to an environment of use. The delivery system comprises a plurality of tiny dosage forms comprising a beneficial agent. The delivery system also comprises means for maintaining (a) the physical and chemical integrity of the dosage form and for (b) inhibiting delivery of the beneficial agent during non-performance of the delivery system.

Abstract: A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chamber. The chamber is adapted for use in an intravenous delivery system for delivering an agent formulation to a patient.

Abstract: A device for releasing active ingredient into a liquid flow passing through a system for parenteral application of the ingredient comprises a receptacle composed of two half shells. The receptacle is subdivided by a ribbed aluminium foil into two chambers and has an inlet at its upper end and an outlet at its lower end. The two chambers have vent means at their upper ends. One of the chambers contains two overflows a first one of which empties into the outlet while the second one empties into the other chamber. In the latter chamber there is present a further overflow which also empties into the outlet, as well as a plate-shaped carrier charged with the active ingredient to be released. The liquid flows from the inlet via the first chamber and the second overflow therein into the other chamber and from there upwardly past a carrier charged with active ingredient, and onward via a third overflow in the other chamber into the outlet.