Patents Assigned to BIOGRAPHENE INC.
  • Patent number: 11786549
    Abstract: The present invention relates to an anti-inflammatory composition comprising a graphene nano-structure as an active ingredient. Specifically, the present invention relates to a pharmaceutical composition for preventing or treating an inflammatory disease, and a cosmetic composition or feed composition for preventing or improving an inflammatory disease, which include the anti-inflammatory composition, and a method of treating an inflammatory disease, including administering the composition to a subject in need thereof.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: October 17, 2023
    Assignees: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BIOGRAPHENE INC.
    Inventors: Kyung-Sun Kang, Byung-Chul Lee, Jin Young Lee, Jong Bo Park
  • Publication number: 20230302161
    Abstract: Provided is a method for preparing a carbon-13-containing graphene quantum dot available as an MRI contrast medium, a carbon-13-containing graphene quantum dot prepared by the method, and an MRI contrast medium comprising the carbon-13 graphene quantum dot.
    Type: Application
    Filed: August 25, 2021
    Publication date: September 28, 2023
    Applicants: BIOGRAPHENE INC., SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION
    Inventors: Byung Hee HONG, Young Jin JUNG, Jong Bo PARK
  • Publication number: 20220096540
    Abstract: Provided is a method for prevention or treatment of a lysosomal storage disorder, and more particularly, to a method that may exhibit excellent efficacy against various lysosomal storage disorders including Niemann-Pick disease by including graphene quantum dots.
    Type: Application
    Filed: January 23, 2020
    Publication date: March 31, 2022
    Applicants: BIOGRAPHENE INC., SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION
    Inventors: Kyung-Sun KANG, Byung Hee HONG, Insung KANG, Je Min YOO, Donghoon KIM
  • Publication number: 20210252051
    Abstract: Provided is a graphene quantum dot as a therapeutic agent for diseases associated with abnormal fibrillation or aggregation of neuroproteins. The graphene quantum dot according to the presently claimed subject matter suppresses ?-syn fibrillation or disaggregates already formed ?-syn fibrils, and shows the working effect of passing through the blood brain barrier (BBB). Therefore, the graphene quantum dot according to the presently claimed subject matter can be advantageously used as a therapeutic agent for diseases associated with abnormal fibrillation and aggregation of neuroproteins, such as neurodegenerative diseases, inflammatory diseases, and metabolic diseases.
    Type: Application
    Filed: July 8, 2019
    Publication date: August 19, 2021
    Applicants: BIOGRAPHENE INC., SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION
    Inventors: Byung Hee HONG, Je Min YOO
  • Publication number: 20210180018
    Abstract: Provided is a composition capable of promoting osteogenic differentiation of stem cells, comprising, as active ingredients, a bone and cartilage progenitor cell culture solution and a multilayer graphene film, which promotes the differentiation of stem cells into specific cells, and thus is expected to be variously applicable in the in vivo/in vitro stem cell application fields.
    Type: Application
    Filed: May 14, 2019
    Publication date: June 17, 2021
    Applicants: SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION, BIOGRAPHENE INC.
    Inventors: Jeong Mook LIM, Ji Yeon AHN, Jong Bo PARK, Byung Hee HONG, Woo Sub YANG
  • Publication number: 20210030808
    Abstract: Provided are a culture scaffold for promoting stem cell differentiation comprising a multilayer graphene film, a method of regulating growth and differentiation of a stem cell using the culture scaffold, and a method of preparing the culture scaffold, where the culture scaffold is capable of promoting the osteogenic differentiation of stem cells as a result of laminating a graphene film without comprising an additional substance, and it may be variously applicable to application fields of stem cells in/outside the body.
    Type: Application
    Filed: April 5, 2019
    Publication date: February 4, 2021
    Applicants: Seoul National University R & DB Foundation, BIOGRAPHENE INC.
    Inventors: Byung Hee HONG, Ji Yeon AHN, Jong Bo PARK, Jeong Mook LIM, Woo Sub YANG
  • Publication number: 20200360429
    Abstract: The present invention relates to an anti-inflammatory composition comprising a graphene nano-structure as an active ingredient. Specifically, the present invention relates to a pharmaceutical composition for preventing or treating an inflammatory disease, and a cosmetic composition or feed composition for preventing or improving an inflammatory disease, which include the anti-inflammatory composition, and a method of treating an inflammatory disease, including administering the composition to a subject in need thereof.
    Type: Application
    Filed: November 23, 2018
    Publication date: November 19, 2020
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, BIOGRAPHENE INC.
    Inventors: Kyung-Sun KANG, Byung-Chul LEE, Jin Young LEE, Jong Bo PARK