Patents Assigned to Cipla Limited
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Patent number: 11931362Abstract: The present invention relates to a long term storage stable multi-dose ready-to use or ready-to dilute pharmaceutical liquid formulation comprising pemetrexed or a pharmaceutically acceptable salt thereof, an antioxidant, a preservative, a buffering agent, and a pharmaceutically acceptable fluid. The invention also relates to a process of preparing the formulation, a kit and a method of treatment of patients having lung cancer by administering the pharmaceutical formulation to a subject in need thereof.Type: GrantFiled: March 3, 2021Date of Patent: March 19, 2024Assignee: Cipla LimitedInventors: Sarabjit Singh, Alagumurugan Alagarswamy, Madhusudhan Malladi, Sandip Gite
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Publication number: 20230181741Abstract: There is provided a complex comprising rifaximin and a complexing agent, wherein the complexing agent is a polyvinyl pyrrolidone (PVP) or a cyclodextrin. There is also provided a process for preparing the complex, a pharmaceutical composition including the complex and therapeutic uses of the complex.Type: ApplicationFiled: July 12, 2022Publication date: June 15, 2023Applicant: CIPLA LIMITEDInventors: Maruti Ganpati Ghagare, Sunilkumar Parasnath Saroj, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
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Publication number: 20230116935Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.Type: ApplicationFiled: May 17, 2022Publication date: April 20, 2023Applicant: CIPLA LimitedInventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
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Patent number: 11612612Abstract: An oral or injectable pharmaceutical composition is provided for treating diseases caused by retroviruses or hepatitis B viruses. The composition comprises a therapeutically effective amount of at least one anti-retroviral drug and a therapeutically effective amount of at least one pharmacokinetic booster or enhancer or derivative thereof. Methods and kits are also provided.Type: GrantFiled: October 15, 2020Date of Patent: March 28, 2023Assignee: CIPLA LIMITEDInventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Preeti Raut
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Patent number: 11596597Abstract: A pharmaceutical long acting depot composition is provided as an aid to smoking cessation treatment. The formulation comprises a therapeutically effective amount of varenicline or its pharmaceutically acceptable derivative and pharmaceutically acceptable excipients. The process of preparation of the formulation is also provided.Type: GrantFiled: February 5, 2021Date of Patent: March 7, 2023Assignee: Cipla LimitedInventors: Geena Malhotra, Sarabjit Singh
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Patent number: 11478483Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of Quetiapine or derivative thereof. The compositions include an effective amount of Quetiapine or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.Type: GrantFiled: September 6, 2018Date of Patent: October 25, 2022Assignee: Cipla LimitedInventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
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Patent number: 11464425Abstract: A flow-sensing arrangement within a spirometer. The arrangement includes a tubular-member for allowing an air-passage along a longitudinal-axis thereof. At-least two disc-shaped air-resistive elements are removably-arranged within the tubular member to resist the air-flow. Each of the resistive-elements include perforations for allowing the air-passage through the resistive-element. At-least two ports extend radially outward through a wall of the tubular member, such that each of the two ports are located within the tubular-member near the resistive-elements to cause determination of at least a pressure-difference there-between.Type: GrantFiled: July 26, 2018Date of Patent: October 11, 2022Assignee: CIPLA LIMITEDInventors: Nandan Kulkarni, Vidur Malhotra, Geena Malhotra, Brinder Ahluwalia
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Patent number: 11390637Abstract: The present invention relates to certain acid salts of (((1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methyl)(phenoxy) phosphoryloxy)methyl pivalate of Formula (I), to processes for their preparation; to pharmaceutical compositions comprising such compounds, and methods of treating a disease which responds to inhibition of nucleotide reverse transcriptase activity.Type: GrantFiled: March 16, 2018Date of Patent: July 19, 2022Assignee: Cipla LimitedInventors: Manjinder Singh Phull, Ashwini Amol Sawant, Dharmaraj Ramachandra Rao, Geena Malhotra, Manish Gopaldas Gangrade
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Patent number: 11267798Abstract: The present application relates to a process for the preparation of piperine of high purity having low concentrations of isomeric impurities.Type: GrantFiled: October 13, 2018Date of Patent: March 8, 2022Assignee: CIPLA LIMITEDInventors: Manjinder Singh Phull, Dharmaraj Ramachandra Rao, Geena Malhortra, Dilip Ramdas Birari, Sachin Vasant Desai
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Patent number: 11234981Abstract: A pharmaceutical composition is provided comprising combination of antiretroviral drugs optionally in combination of pharmacokinetic boosters. The formulation is used for the treatment of diseases caused by retroviruses. The process of preparation of the formulation is also provided.Type: GrantFiled: April 18, 2018Date of Patent: February 1, 2022Assignee: Cipla LimitedInventors: Geena Malhotra, Kalpana Joshi, Preeti Raut
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Patent number: 11224591Abstract: A pharmaceutical composition is provided for the treatment of systemic infections as well as colonic diseases. The composition comprises a therapeutically effective amount of rifaximin and a therapeutically effective amount of at least one alkaloid or derivative thereof. Methods and kits are also provided.Type: GrantFiled: October 13, 2017Date of Patent: January 18, 2022Assignee: Cipla LimitedInventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
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Patent number: 11207319Abstract: Methods of treating bladder cancer using terconazole are disclosed herein. Terconazole can be administered as part of a comprehensive treatment program, which can also include chemotherapy, immunotherapy, radiation therapy and/or surgical treatment.Type: GrantFiled: November 6, 2018Date of Patent: December 28, 2021Assignee: Cipla LimitedInventors: Geena Malhotra, Kalpana Joshi
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Publication number: 20210308150Abstract: A pharmaceutical composition for inhalation comprising R (+) budesonide and one or more bronchodilators, and, optionally, one or more pharmaceutically acceptable excipients is described.Type: ApplicationFiled: June 15, 2021Publication date: October 7, 2021Applicant: CIPLA LimitedInventors: Geena Malhotra, Shrinivas Madhukar Purandare, Amar Lulla
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Patent number: 11129836Abstract: Disclosed herein are methods of treating cancers by administration of a PAR-4 agonist.Type: GrantFiled: May 23, 2019Date of Patent: September 28, 2021Assignee: Cipla LimitedInventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
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Patent number: 11077124Abstract: A pharmaceutical composition for inhalation comprising R (+) budesonide and one or more bronchodilators, and, optionally, one or more pharmaceutically acceptable excipients is described.Type: GrantFiled: July 10, 2017Date of Patent: August 3, 2021Assignee: CIPLA LimitedInventors: Geena Malhotra, Shrinivas Madhukar Purandare, Amar Lulla
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Patent number: 10987305Abstract: A method for the preparation of respirable zafirlukast monohydrate particles comprises the steps of preparation of an aqueous suspension of amorphous zafirlukast; size-reduction with conversion of the suspended zafirlukast into crystalline monohydrate nanoparticles; and isolation of the crystalline zafirlukast in the form of a dry powder. Also provided are zafirlukast respirable particles characterized by comprising crystalline monohydrate zafirlukast. Pharmaceutical compositions comprising the particles are also disclosed, as is the use of the particles or compositions for the treatment of respiratory diseases.Type: GrantFiled: December 15, 2016Date of Patent: April 27, 2021Assignee: Cipla LimitedInventors: Eunice Costa, Susana Campos, Filipe Neves
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Patent number: 10966982Abstract: The present invention relates to a long term storage stable multi-dose ready-to use or ready-to dilute pharmaceutical liquid formulation comprising pemetrexed or a pharmaceutically acceptable salt thereof, an antioxidant, a preservative, a buffering agent, and a pharmaceutically acceptable fluid. The invention also relates to a process of preparing the formulation, a kit and a method of treatment of patients having lung cancer by administering the pharmaceutical formulation to a subject in need thereof.Type: GrantFiled: November 20, 2019Date of Patent: April 6, 2021Assignee: Cipla LimitedInventors: Sarabjit Singh, Alagumurugan Alagarswamy, Madhusudhan Malladi, Sandip Gite
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Patent number: 10940274Abstract: A nasal spray assembly for administering a medicament to the nose of a user includes a nasal device and a container that has a reservoir containing the medicament. The reservoir is sealed by a movable piston. The nasal device includes a body, a cap that defines a socket into which the body can be inserted, an outlet, and a piercing element. The piercing element includes a piercer inlet and extends into the socket from a piercer stop within the socket. The nasal spray assembly is arranged such that, as the body is moved into the socket along a first axis, the piercing element pierces and passes through the piston such that the piercer inlet lies within the reservoir, contact between the piercer stop and piston forces the piston into the container, reducing the reservoir volume and forcing medicament from the reservoir through the conduit and out of the outlet.Type: GrantFiled: December 1, 2016Date of Patent: March 9, 2021Assignee: CIPLA LIMITEDInventors: Geena Malhotra, Dinakaran Govindasamy
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Patent number: 10933047Abstract: Disclosed herein are improved formulations for the cabazitaxel. The formulations exhibit increased storage stability relative to other formulations, and are simpler for health care providers to prepare and administer to patients.Type: GrantFiled: December 19, 2017Date of Patent: March 2, 2021Assignee: Cipla LimitedInventors: Geena Malhotra, Sarabjit Singh, Ravichandra Bhadravathi Vedamurthy, Anirban Mallik Thakur, Dhiraj Abhyankar
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Patent number: 10912734Abstract: A pharmaceutical long acting depot composition is provided as an aid to smoking cessation treatment. The formulation comprises a therapeutically effective amount of varenicline or its pharmaceutically acceptable derivative and pharmaceutically acceptable excipients. The process of preparation of the formulation is also provided.Type: GrantFiled: May 15, 2019Date of Patent: February 9, 2021Assignee: Cipla LimitedInventors: Geena Malhotra, Sarabjit Singh