Patents Assigned to National Taiwan University
  • Publication number: 20240165233
    Abstract: The present invention relates to a method for reducing localized fat deposits in a subject in need thereof in need thereof by topically treating the subject with rare-earth element doped calcium carbonate particles in combination with low-intensity ultrasound. The rare-earth element doped calcium carbonate particles have good biocompatibility and can increase reactive oxygen species (ROS) production and produce carbon dioxide (CO2) and calcium ions (Ca2+) in the region of administration under the ultrasonic irradiation. The method of the present invention is effective in inducing adipocyte necrosis, inhibiting adipogenesis, and decreasing body weight and useful for body sculpture.
    Type: Application
    Filed: November 17, 2022
    Publication date: May 23, 2024
    Applicants: National Health Research Institutes, National United University, National Taiwan University
    Inventors: Feng-Huei LIN, Gin-Shin CHEN, Ping-Yu SHIH, Ching-Yun CHEN, Li-Ze LIN, Che-Yung KUAN, Zhi-Yu CHEN, I-Hsuan YANG
  • Patent number: 11986285
    Abstract: A disease diagnosing method and a disease diagnosing system are provided in the disclosure. The disease diagnosing method includes: obtaining continuous images of a body skin and generating a time domain signal according to an average pixel value of a region of interest in each frame of the continuous images; transforming the time domain signal to a frequency domain signal and combining the time domain signal and the frequency domain signal to a time frequency signal; retrieving multiple first features of a first high dimensional space of the time frequency signal to obtain multiple second features of a second high dimensional space; and use the second features as feature vectors to map to a high dimension feature space, and classifying the second features as one of the multiple categories of a disease corresponding to the region of interest in the body skin according to a hyperplane of the high dimension feature space.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: May 21, 2024
    Assignee: National Taiwan University
    Inventors: Hao-Ming Hsiao, Hsien-Li Kao, Mao-Shin Lin, Chung-Yuan Hsu
  • Patent number: 11974506
    Abstract: A spin-orbit torque device is disclosed, which includes: a magnetic layer; and a non-magnetic layer adjacent to the magnetic layer and comprising a spin-Hall material, wherein the spin-Hall material comprises NixCu1-x alloy, and x is in a range from 0.4 to 0.8.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: April 30, 2024
    Assignees: NATIONAL TAIWAN UNIVERSITY, ACADEMIA SINICA
    Inventors: Po-Hsun Wu, Ssu-Yen Huang, Chia-Ling Chien, Danru Qu
  • Patent number: 11964428
    Abstract: The present invention provides a bottom plate of a resin tank for three-dimensional printing, which is manufactured through the following steps: substrate surface roughening step: treating the upper surface of a transparent substrate by using a plasma, or disposing a composite film on the upper surface of the transparent substrate to form a non-smooth surface structure having pores; substrate surface modification step: sequentially performing an activation treatment and a fluorination treatment on the upper surface of the transparent substrate; and stabilizer filling step: applying a stabilizer to the upper surface of the transparent substrate to fill the stabilizer penetrates into the pores on the upper surface of the transparent substrate. The low surface energy film reduces the adhesion of the hardened photosensitive material, and the stabilizer maintains the structure of the low surface energy film, so that the resin tank bottom plate has both oleophobic and hydrophobic properties.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: April 23, 2024
    Assignee: National Taiwan University of Science and Technology
    Inventors: Jeng-Ywan Jeng, Ming-Hua Ho, Ping-Hsun Tsai
  • Publication number: 20240128626
    Abstract: A transmission device includes a daisy chain structure composed of at least three daisy chain units arranged periodically and continuously. Each of the daisy chain units includes first, second and third conductive lines, and first and second conductive pillars. The first and second conductive lines at a first layer extend along a first direction and are discontinuously arranged. The third conductive line at a second layer extends along the first direction and is substantially parallel to the first and second conductive lines. The first conductive pillar extends in a second direction. The second direction is different from the first direction. A first part of the first conductive pillar is connected to the first and third conductive lines. The second conductive pillar extends in the second direction. A first part of the second conductive pillar is connected to the second and third conductive lines.
    Type: Application
    Filed: November 25, 2022
    Publication date: April 18, 2024
    Applicants: UNIMICRON TECHNOLOGY CORP., National Taiwan University
    Inventors: Yu-Kuang WANG, Ruey-Beei Wu, Ching-Sheng Chen, Chun-Jui Huang, Wei-Yu Liao, Chi-Min Chang
  • Publication number: 20240130038
    Abstract: A transmission device for suppressing the glass-fiber effect includes a circuit board and a transmission line. The circuit board includes a plurality of glass fibers, so as to define a fiber pitch. The transmission line is disposed on the circuit board. The transmission line includes a plurality of non-parallel segments. Each of the non-parallel segments of the transmission line has an offset distance with respect to a reference line. The offset distance is longer than or equal to a half of the fiber pitch.
    Type: Application
    Filed: November 23, 2022
    Publication date: April 18, 2024
    Applicants: UNIMICRON TECHNOLOGY CORP., National Taiwan University
    Inventors: Chin-Hsun WANG, Ruey-Beei Wu, Ching-Sheng Chen, Chun-Jui Hung, Wei-Yu Liao, Chi-Min Chang
  • Patent number: 11952467
    Abstract: A method for processing a polyalkylene benzenedicarboxylate material includes subjecting a polyalkylene benzenedicarboxylate material to an immersion treatment with an immersion liquid including ethylene glycol, so as to obtain an immersed polyester material, and subjecting the immersed polyester material to a disintegration treatment to obtain a disintegrated polyester material. The immersed polyester material has crystallinity higher than that of the polyalkylene benzenedicarboxylate material.
    Type: Grant
    Filed: February 8, 2022
    Date of Patent: April 9, 2024
    Assignee: National Taiwan University
    Inventors: Chia-Wen Wu, Wei-Sheng Liao, Yu-Wen Chiao
  • Patent number: 11952484
    Abstract: An electrical responsive graphene-PVDF material and the manufacturing method thereof is disclosed in the present invention. The method includes three steps. Firstly, prepare a mother solution of PVDF. Then, add graphene powders into the mother solution of PVDF to prepare a graphene-PVDF slurry. At last, remove the solvent from the graphene-PVDF slurry to directly form an electrical responsive graphene-PVDF material. Due to the ability of transforming the non-electrical energy into the electrical energy, the electrical responsive graphene-PVDF material can be formed for many different applications in the form of individual film or of film with a substrate via various film formation methods.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: April 9, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wei-Sung Hung, Jian-Xiang Huang
  • Patent number: 11952469
    Abstract: The present disclosure provides a method for preparing a hydrogel composition with thermos-sensitive and ionic reversible properties and the hydrogel composition prepared by the method. Related application products of the hydrogel composition of the present disclosure include wound dressings, drug carriers, three-dimensional cellular scaffolds, soluble microspheres, and cell capture and release systems, wherein the hydrogel composition with thermos-sensitive and ionic reversible properties has good in vitro and in vivo stability and high biocompatibility, and is non-toxic. The hydrogel composition can be removed and replaced by washing with metal chelating aqueous solution at low temperature.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: April 9, 2024
    Assignee: National Taiwan University of Science and Technology
    Inventors: Hsieh-Chih Tsai, Shuian-Yin Lin, Hsiao-Ying Chou
  • Patent number: 11952498
    Abstract: Disclosed herein are a colored functionalized paracyclophane represented by Formula (I) and a colored chemical film represented by Formula (II): wherein A, o, and p in Formula (I) and Formula (II) are as defined herein. The colored chemical film may be formed from the colored functionalized [2,2]paracyclophane by chemical vapor deposition.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: April 9, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Hsien-Yeh Chen, Sheng-Tung Huang
  • Patent number: 11947134
    Abstract: A device is provided to generate a three-dimensional (3D) real image. A display panel is divided into several sub-areas for emitting scenes. Through a projecting lens-array unit, the scenes enter a fusion lens unit to form a real image of light field at a position beyond common barrier. Through an eyepiece unit, the image is emitted to human eye. Thus, the present invention provides a device for near-eye viewing, which reduces existing human-eye vergence accommodation conflict (VAC) in most augmented reality and mixed reality devices. Therein, the display of near-eye light field is a process of light-field reproduction, which merges the scenes and reduces aberration.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: April 2, 2024
    Assignee: National Taiwan University
    Inventors: Jiun-Woei Huang, Chang-Le Liu, Hong-Ming Chen, Kuang-Tsu Shih
  • Patent number: 11932931
    Abstract: The present invention relates to a hydrophilic metal thin film, which is formed by stacking a plurality of columnar structures. A plurality of tetrahedral structures is on the surface of the hydrophilic metal film, which is formed on the top of the columnar structures. The width of the tetrahedral structures is 15 nm to 120 nm. The hydrophilic metal thin film comprises: 35 to 95 at % of iron, 5 to 20 at % of chromium. The above-mentioned hydrophilic metal thin film is formed by magnetron sputtering method under the working pressure of argon gas ranging from 6 mTorr to 13 mTorr, and the sputtering time exceeds 20 minutes.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: March 19, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Pak-Man Yiu, Jhen-De You, Jinn Chu, Sung-Tsun Wang
  • Publication number: 20240081732
    Abstract: The present invention discloses a method of detecting sleep disorder based on an EEG signal and device of the same. The method and device only need an EEG signal for analysis to determine sleep disorder and abnormal score. Therefore, the method and device may reduce cost of collecting physical information and avoid from uncomfortable feeling of user who wears several sensors.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 14, 2024
    Applicant: National Taiwan University
    Inventors: Phone LIN, XIN-XUE LIN
  • Publication number: 20240085369
    Abstract: Disclosed is a self-powered formaldehyde sensing device, comprising: a triboelectric material electrode layer including a first substrate and a first electrode layer formed on the first substrate; a triboelectric material dielectric layer including a second substrate, a second electrode layer formed on the second substrate, a dielectric reacting layer formed on the second electrode layer, and a reaction modification layer formed on the dielectric reacting layer to surface-modify the dielectric reacting layer, the reaction modification layer being a phosphomolybdic acid complex (cPMA) layer, the phosphomolybdic acid complex of the phosphomolybdic acid complex layer being obtained by dissolving 4,4?-bipyridine (BPY) in isopropanol (IPA) and then mixing with phosphomolybdic acid (PMA) solution; an elastic spacer; and an external circuit.
    Type: Application
    Filed: December 21, 2022
    Publication date: March 14, 2024
    Applicant: National Taiwan University of Science and Technology
    Inventors: Chih-Yu Chang, Chun-Yi Ho, Yu-Hsuan Cheng, Ying-Ying Chen
  • Patent number: 11925727
    Abstract: An intervertebral fusion device includes a structural ceramic body. The structural ceramic body has a bottom surface, a top surface, a peripheral surface connected between the bottom surface and the top surface, and at least one pore channel penetrating the bottom surface and the top surface. The inner surface of the pore channel is either a convex curved surface or a funnel-shaped surface. For the pore channel having the convex curved surface, the pore diameter of the pore channel gradually expands from the center of the pore channel to the top surface and the bottom surface. The pore diameter can also gradually expand from the bottom surface to the top surface. The peripheral surface of the structural ceramic body is wavy or zigzag.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: March 12, 2024
    Assignee: National Taiwan University
    Inventor: Wei-Hsing Tuan
  • Patent number: 11925650
    Abstract: The present invention provides an antibacterial chemical compound, its manufacturing method and its use thereof which acts as antibacterial agents being useful for treating a disease or condition characterized by infectious disease, such as gastroenteritis and invasive non-typhoidal Salmonellosis, and also providing a new therapeutic option for patients infected by the bacteria with the resistance to antibiotics.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: March 12, 2024
    Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL YANG MING CHIAO TUNG UNIVERSITY
    Inventors: Hao-Chieh Chiu, Chung-Wai Shiau
  • Patent number: 11919886
    Abstract: The present disclosure provides compounds of Formulas (I), (II), and pharmaceutically acceptable salts thereof. The compounds described herein are useful in treating proliferative diseases, for example, cancer (e.g., lung cancer), and infectious diseases (e.g., bacterial infections).
    Type: Grant
    Filed: July 12, 2022
    Date of Patent: March 5, 2024
    Assignees: Academia Sinica, National Taiwan University
    Inventors: Chi-Huey Wong, Pan-Chyr Yang, Rong-Jie Chein, Szu-Hua Pan, Ting-Jen R. Cheng
  • Publication number: 20240068043
    Abstract: Provided is a method for diagnosing and monitoring progression of cancer or effectiveness of a therapeutic treatment. The method includes detecting a methylation level of at least one gene in a biological sample containing circulating free DNA. Also provided are primer pairs and probes for diagnosis or prognosis of cancer in a subject in need thereof.
    Type: Application
    Filed: March 1, 2022
    Publication date: February 29, 2024
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Hsing-Chen TSAI, Chong-Jen YU, Hsuan-Hsuan LU, Shu-Yung LIN, Yi-Jhen HUANG, Chen-Yuan DONG
  • Patent number: 11913030
    Abstract: The present disclosure provides a method of preparing mimicking angiogenic co-spheroids, including: co-cultring a neural related cell and a cultured cell on hyaluronan-grafted chitosan (CS-HA) substrates to form a co-spheroid of neural related cell/cultured cell, and encapsulating the co-spheroid of neural related cell/cultured cell into a hydrogel to form a mimicking angiogenic co-spheroid. The mimicking angiogenic co-spheroid of the present disclosure can be formed by 3D printing model as a 3D mini-neurovascular unit, which is applicated to a high-throughput angiogenesis screening platform.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: February 27, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Shan-Hui Hsu, Hao-Wei Han
  • Patent number: 11910791
    Abstract: A graded early warning system for pest quantity counting includes: at least one image capturing device used to capture images of at least one pest trapping device in an environment to generate at least one pest trapping image; at least one environment monitoring and sensing device used to detect the environment to generate at least one environment parameter; at least one pest detecting and identifying device used to detect quantities and species of multiple pests based on the at least one pest trapping image; and a cloud server used to receive the at least one pest trapping image, the at least one environment parameter, and the quantities and species of multiple pests; wherein the cloud server immediately establishes pest probability models, generates early warning signals, and prompts suppression decisions according to the at least one environment parameter and the quantities and species of multiple pests.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: February 27, 2024
    Assignee: National Taiwan University
    Inventors: Ta-Te Lin, Dan Jeric Arcega Rustia, Lin-Ya Chiu