Abstract: Methods and therapeutic combinations are provided for treating idiopathic intracranial hypertension (IIH) and cluster headache, comprising administering a somatostatin mimetic such as octreotide formulated for direct nose-to-brain administration, and a carbonic anhydrase inhibitor such as topiramate or acetazolamide, at a dose level and/or dosing regimen lower than effective when administered alone.
Type:
Application
Filed:
February 23, 2022
Publication date:
April 25, 2024
Applicant:
NBO PHARMA LLC
Inventors:
Fredric D. PRICE, Barry R. FRANKEL, Dorian BEVEC, Warren WASIEWSKI