Patents Assigned to United States Department of Agriculture
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Publication number: 20200038866Abstract: A system for and methods of analyzing a test sample through the use of a rotary apparatus that includes a microfluidic paper-based apparatus (mPAD). The apparatus includes two or more layers that are rotatable with respect to one another. A middle layer may comprise a microfluidic apparatus having one or more reagent channels. Each of the reagent channels may include reagent dried on the surface of the channel, and, together with an adsorption pad, may be aligned vertically with a sample chamber. Male and female engagement surfaces on each of the middle layer, the top layer, and the bottom layer interlock to secure each layers in vertical alignment so that fluid flows through the apparatus to contact a test sample with a reagent and facilitate detection of a target analyte in the test sample in the sample chamber.Type: ApplicationFiled: August 2, 2019Publication date: February 6, 2020Applicants: Colorado State University Research Foundation, United States Department of AgricultureInventors: Charles S. HENRY, Rachel FEENY, Alan B. FRANKLIN, Cody CARRELL
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Patent number: 9669004Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.Type: GrantFiled: January 15, 2015Date of Patent: June 6, 2017Assignees: The Administrators of the Tulane Educational Fund, United States Department of Agriculture, Xavier University of LouisianaInventors: Guangdi Wang, Matthew E. Burow, Stephen M. Boue, Thomas E. Wiese, Quan Jiang
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Patent number: 8987198Abstract: Disclosed are methods of modulating the expression of genes linked to adipocytokine signaling, carbohydrate metabolism, fatty acid metabolism, arachidonic acid metabolism, PPAR signaling, insulin signaling, lipid metabolism, extracellular matrix (ECM)-receptor interaction, or combinations thereof, methods of treating hyperlipidemia, obesity, excessive cholesterol, cardiovascular disease, liver disease, diabetes, or combinations thereof, and methods of stimulating glucose uptake in an animal in need thereof, comprising administering a composition comprising at least one isolated glyceollin to said animal.Type: GrantFiled: December 22, 2010Date of Patent: March 24, 2015Assignees: The Administrators of the Tulane Educational Fund, The United States Department of Agriculture, Wake Forest University Health Sciences, Nume Health, LLCInventors: Matthew E. Burow, Stephen M. Boue, Thomas T. Y. Wang, Deepak Bhatnagar, Charles E. Wood, Mark L. Helman
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Publication number: 20130184475Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.Type: ApplicationFiled: July 8, 2011Publication date: July 18, 2013Applicants: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, XAVIER UNIVERSITY OF LOUISIANNA, UNITED STATES DEPARTMENT OF AGRICULTUREInventors: Guangdi Wang, Matthew E. Burow, Stephen M. Boue, Thomas E. Wiese, Quan Jiang
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Publication number: 20130041022Abstract: The present disclosure demonstrates the molecular effects of glyceollins on human prostate cancer cell LNCaP to further elucidate its potential effects on prostate cancer prevention. The glyceollins inhibited LNCaP cell growth similar to that of the soy isoflavone genistein. The growth inhibitory effects of the glyceollins appeared to be due to an inhibition on G1/S progression and correlated with an up-regulation of cyclin-dependent kinase inhibitor A1 and B1 mRNA and protein levels. By contrast, genistein only up-regulates cyclin-dependent kinase inhibitor A1. In addition, glyceollin treatments led to down-regulated mRNA levels for androgen responsive genes. In contrast to genistein, this effect of glyceollins on androgen responsive genes appeared to be mediated through modulation of an estrogen- but not androgen-mediated pathway.Type: ApplicationFiled: December 22, 2009Publication date: February 14, 2013Applicants: UNITED STATES DEPARTMENT OF AGRICULTURE, THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Thomas E. Cleveland, Stephen M. Boue, Matthew E. Burow, Thomas T.Y. Wang
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Patent number: 8357353Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an O, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.Type: GrantFiled: May 10, 2010Date of Patent: January 22, 2013Assignees: Biotechnology Research & Development Corporation, United States Department of AgricultureInventors: Joseph A. Laszlo, David L. Compton, Louis J. DeFilippi, Steven Grall
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Publication number: 20110130360Abstract: A water-insoluble cellulose derivative, such as ethyl cellulose is useful for preventing or reducing oxidative stress or oxidative cell injury in tissues of an animal and in particular for influencing the level Stearoyl-CoA Desaturase-1 (SCD1) gene expression or ATP synthase mitochondrial F1 complex assembly factor 1 (ATPAF1) gene expression in non-adipose tissues of the animal.Type: ApplicationFiled: October 18, 2007Publication date: June 2, 2011Applicants: DOW GLOBAL TECHNOLOGIES INC., UNITED STATES DEPARTMENT OF AGRICULTUREInventors: Stephanie K. Lynch, Wallace H. Yokoyama, Maciej Turowski
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Publication number: 20110098180Abstract: Described are polynucleotides having nucleotide sequences encoding mutant plant phytoene desaturase proteins that are resistant the bleaching herbicides that act on phytoene desaturase, and related nucleic acid constructs, plants and methods.Type: ApplicationFiled: July 17, 2003Publication date: April 28, 2011Applicant: United States Department of AgricultureInventors: Albrecht Michel, Michael D. Netherland, Brian E. Scheffler, Franck E. Dayan, Renee S. Arias De Ares
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Publication number: 20100215600Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an 0, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.Type: ApplicationFiled: May 10, 2010Publication date: August 26, 2010Applicants: BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION, UNITED STATES DEPARTMENT OF AGRICULTUREInventors: Joseph A. Laszlo, David L. Compton, Louis J. DeFilippi, Steven Grall
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Publication number: 20100190924Abstract: This invention relates to electrically conductive and non-conductive polymer composite materials suitable for use as polymer composites, electrically conductive materials, electromagnetic wave shielding materials, heating elements, antistatic materials, substitute for existing polymer composites, and the like. The invention also relates to methods of making the electrically conductive and non-conductive polymer composite materials, and compositions containing the polymer composites also are disclosed herein.Type: ApplicationFiled: June 30, 2008Publication date: July 29, 2010Applicant: UNITED STATES DEPARTMENT OF AGRICULTUREInventor: Sanghoon Kim
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Patent number: 7591881Abstract: This invention provides novel devices and methods for manipulation of moisture/fluid levels in and/or upon objects and is used to, e.g., safely dry wet books and documents with minimal deleterious side effects or to add humidity to such books/documents or other objects or areas.Type: GrantFiled: September 29, 2005Date of Patent: September 22, 2009Assignees: Artifex Equipment, Inc., The United States of America as represented by the United States Department of AgricultureInventors: Nicholas G. Yeager, Kathleen C. Hayes
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Publication number: 20090117247Abstract: A starch-lipid composite and related composition are described that enhance yield and sensory properties of low fat ground meat. Techniques are described herein for improving the taste and characteristics of ground meat and foods using such, by incorporation of the composite and/or the noted composition.Type: ApplicationFiled: November 7, 2008Publication date: May 7, 2009Applicants: UNITED STATES DEPARTMENT OF AGRICULTURE, HERITAGE FARE, LTD.Inventors: Frederick C. Felker, George F. Fanta, Robert L. Kalebic, Wendell E. Turner
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Publication number: 20070077636Abstract: A method of making a compound having the structural formula: wherein at least two of R1, R2, and R3 are non-fatty acid carboxylates, and the other of R1, R2, and R3 are each either a C2-C24 fatty acid moiety, OH, or a non-fatty acid carboxylate, wherein the first and second non-fatty acid carboxylates, when present, are the same or different, comprising (a) partially deacylating a triacylglycerol so as to provide a mono- or diacylglycerol, (b) reacting in a reaction mixture an acyl ester of the phytochemical with said mono- or diacylglycerol in the presence of a esterase catalyst under conditions that permit transesterification of said ester with said mono- or diacylglycerol, and (c) recovering said compound from said reaction mixture.Type: ApplicationFiled: June 19, 2006Publication date: April 5, 2007Applicants: Biotechnology Research & Development Corporation, United States Department of AgricultureInventors: Joseph Laszlo, David Compton, Louis DeFilippi, Steven Grall
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Publication number: 20070077214Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an 0, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.Type: ApplicationFiled: June 19, 2006Publication date: April 5, 2007Applicants: Biotechnology Research & Development Corporation, United States Department of AgricultureInventors: Joseph Laszlo, David Compton, Louis DeFilippi, Steven Grall
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Publication number: 20040248285Abstract: A fluorescent spectroscopic method and apparatus for real time direct detection of transmissible spongiform encephalopathies in central nervous system tissue by monitoring the fluorescence of intrinsic markers in the tissue by illuminating the tissue with UV or visible light having an appropriate wavelength, and the resulting emission spectra is detected and examined in the region from 350 to 650 nm. A higher intensity in this region is indicative of infected tissue. The apparatus and method would not interfere with existing slaughterhouse line speeds or procedures, and could be used on live animals.Type: ApplicationFiled: August 8, 2003Publication date: December 9, 2004Applicants: eMerge Interactive, Inc., Iowa State University Research Foundation, Inc., United States Department of AgricultureInventors: Thomas A. Casey, Mark A. Rasmussen, Albin H. Gapsch, Ricky Lee Flick, Jacob W. Petrich
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Patent number: 6689397Abstract: Snake repellents include a repellent composition, an inert carrier and an adjuvant. The snake repellents include an essential oil selected from a group of essentials oils or a reagent from one of the essential oils. Methods of repelling snakes include exposing snakes to the snake repellents by aerosol, vapor or fog.Type: GrantFiled: December 17, 2001Date of Patent: February 10, 2004Assignee: The United States of America as represented by the United States Department of AgricultureInventors: Larry Clark, John A. Shivik, Jr.
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Patent number: 6296879Abstract: A method to improve the health and growth of suckling dairy calves on dairy farms includes supplementing calves' diets with a ruminal fluid preparation obtained from the rumen of a cow. This supplement provides the calves with the protection needed to develop faster and healthier. It also leads to a decreased incidence of scours in the treated calves.Type: GrantFiled: September 8, 1999Date of Patent: October 2, 2001Assignees: Cornell Research Foundation, Inc., The United States of America as represented by the United States Department of AgricultureInventors: Thomas V. Muscato, James B. Russell
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Patent number: 6156956Abstract: ACC synthases of higher plants are coded by multigene families; only certain members of these families are responsible for various plant development characteristics effected by ethylene. Control of the processes in plants which are mediated by ACC synthase, such as fruit ripening, can be effected by controlling expression of the relevant ACC synthase gene. In addition, comparison of the amino acid and nucleotide sequence of the ACC synthases from cucumber and tomato provides consensus sequences that permit the design of PCR primers that permit the isolation of ACC synthases from a variety of higher plants.Type: GrantFiled: March 2, 1998Date of Patent: December 5, 2000Assignee: The United States of America as represented by the United States Department of AgricultureInventors: Athanasios Theologis, Takahido Sato
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Patent number: 6060521Abstract: Aqueous dispersion of a particulate solid containing a low boiling organic liquid in which the particulate solid has a hydrophobic outer surface which is suitable for applying to a substrate to form a continuous hydrophobic film thereon.Type: GrantFiled: October 29, 1998Date of Patent: May 9, 2000Assignee: Engelhard Corporation United States Department of AgricultureInventors: Dennis G. Sekutowski, Gary J. Puterka, David Michael Glenn
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Patent number: 5996276Abstract: A method and aerodynamic transport body for delivering biological control agents into a field is provided. The aerodynamic transport body is a biodegradable device into which the biological control agent is placed and then the device is projected into the field using a catapult.Type: GrantFiled: September 18, 1997Date of Patent: December 7, 1999Assignee: The United States of America as represented by the United States Department of AgricultureInventors: Lyle Marvin Carter, Joseph H. Chesson, John Victor Penner