Patents Assigned to United States Department of Agriculture
  • Publication number: 20200038866
    Abstract: A system for and methods of analyzing a test sample through the use of a rotary apparatus that includes a microfluidic paper-based apparatus (mPAD). The apparatus includes two or more layers that are rotatable with respect to one another. A middle layer may comprise a microfluidic apparatus having one or more reagent channels. Each of the reagent channels may include reagent dried on the surface of the channel, and, together with an adsorption pad, may be aligned vertically with a sample chamber. Male and female engagement surfaces on each of the middle layer, the top layer, and the bottom layer interlock to secure each layers in vertical alignment so that fluid flows through the apparatus to contact a test sample with a reagent and facilitate detection of a target analyte in the test sample in the sample chamber.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicants: Colorado State University Research Foundation, United States Department of Agriculture
    Inventors: Charles S. HENRY, Rachel FEENY, Alan B. FRANKLIN, Cody CARRELL
  • Patent number: 9669004
    Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: June 6, 2017
    Assignees: The Administrators of the Tulane Educational Fund, United States Department of Agriculture, Xavier University of Louisiana
    Inventors: Guangdi Wang, Matthew E. Burow, Stephen M. Boue, Thomas E. Wiese, Quan Jiang
  • Patent number: 8987198
    Abstract: Disclosed are methods of modulating the expression of genes linked to adipocytokine signaling, carbohydrate metabolism, fatty acid metabolism, arachidonic acid metabolism, PPAR signaling, insulin signaling, lipid metabolism, extracellular matrix (ECM)-receptor interaction, or combinations thereof, methods of treating hyperlipidemia, obesity, excessive cholesterol, cardiovascular disease, liver disease, diabetes, or combinations thereof, and methods of stimulating glucose uptake in an animal in need thereof, comprising administering a composition comprising at least one isolated glyceollin to said animal.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: March 24, 2015
    Assignees: The Administrators of the Tulane Educational Fund, The United States Department of Agriculture, Wake Forest University Health Sciences, Nume Health, LLC
    Inventors: Matthew E. Burow, Stephen M. Boue, Thomas T. Y. Wang, Deepak Bhatnagar, Charles E. Wood, Mark L. Helman
  • Publication number: 20130184475
    Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.
    Type: Application
    Filed: July 8, 2011
    Publication date: July 18, 2013
    Applicants: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, XAVIER UNIVERSITY OF LOUISIANNA, UNITED STATES DEPARTMENT OF AGRICULTURE
    Inventors: Guangdi Wang, Matthew E. Burow, Stephen M. Boue, Thomas E. Wiese, Quan Jiang
  • Publication number: 20130041022
    Abstract: The present disclosure demonstrates the molecular effects of glyceollins on human prostate cancer cell LNCaP to further elucidate its potential effects on prostate cancer prevention. The glyceollins inhibited LNCaP cell growth similar to that of the soy isoflavone genistein. The growth inhibitory effects of the glyceollins appeared to be due to an inhibition on G1/S progression and correlated with an up-regulation of cyclin-dependent kinase inhibitor A1 and B1 mRNA and protein levels. By contrast, genistein only up-regulates cyclin-dependent kinase inhibitor A1. In addition, glyceollin treatments led to down-regulated mRNA levels for androgen responsive genes. In contrast to genistein, this effect of glyceollins on androgen responsive genes appeared to be mediated through modulation of an estrogen- but not androgen-mediated pathway.
    Type: Application
    Filed: December 22, 2009
    Publication date: February 14, 2013
    Applicants: UNITED STATES DEPARTMENT OF AGRICULTURE, THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
    Inventors: Thomas E. Cleveland, Stephen M. Boue, Matthew E. Burow, Thomas T.Y. Wang
  • Patent number: 8357353
    Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an O, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: January 22, 2013
    Assignees: Biotechnology Research & Development Corporation, United States Department of Agriculture
    Inventors: Joseph A. Laszlo, David L. Compton, Louis J. DeFilippi, Steven Grall
  • Publication number: 20110130360
    Abstract: A water-insoluble cellulose derivative, such as ethyl cellulose is useful for preventing or reducing oxidative stress or oxidative cell injury in tissues of an animal and in particular for influencing the level Stearoyl-CoA Desaturase-1 (SCD1) gene expression or ATP synthase mitochondrial F1 complex assembly factor 1 (ATPAF1) gene expression in non-adipose tissues of the animal.
    Type: Application
    Filed: October 18, 2007
    Publication date: June 2, 2011
    Applicants: DOW GLOBAL TECHNOLOGIES INC., UNITED STATES DEPARTMENT OF AGRICULTURE
    Inventors: Stephanie K. Lynch, Wallace H. Yokoyama, Maciej Turowski
  • Publication number: 20110098180
    Abstract: Described are polynucleotides having nucleotide sequences encoding mutant plant phytoene desaturase proteins that are resistant the bleaching herbicides that act on phytoene desaturase, and related nucleic acid constructs, plants and methods.
    Type: Application
    Filed: July 17, 2003
    Publication date: April 28, 2011
    Applicant: United States Department of Agriculture
    Inventors: Albrecht Michel, Michael D. Netherland, Brian E. Scheffler, Franck E. Dayan, Renee S. Arias De Ares
  • Publication number: 20100215600
    Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an 0, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.
    Type: Application
    Filed: May 10, 2010
    Publication date: August 26, 2010
    Applicants: BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION, UNITED STATES DEPARTMENT OF AGRICULTURE
    Inventors: Joseph A. Laszlo, David L. Compton, Louis J. DeFilippi, Steven Grall
  • Publication number: 20100190924
    Abstract: This invention relates to electrically conductive and non-conductive polymer composite materials suitable for use as polymer composites, electrically conductive materials, electromagnetic wave shielding materials, heating elements, antistatic materials, substitute for existing polymer composites, and the like. The invention also relates to methods of making the electrically conductive and non-conductive polymer composite materials, and compositions containing the polymer composites also are disclosed herein.
    Type: Application
    Filed: June 30, 2008
    Publication date: July 29, 2010
    Applicant: UNITED STATES DEPARTMENT OF AGRICULTURE
    Inventor: Sanghoon Kim
  • Patent number: 7591881
    Abstract: This invention provides novel devices and methods for manipulation of moisture/fluid levels in and/or upon objects and is used to, e.g., safely dry wet books and documents with minimal deleterious side effects or to add humidity to such books/documents or other objects or areas.
    Type: Grant
    Filed: September 29, 2005
    Date of Patent: September 22, 2009
    Assignees: Artifex Equipment, Inc., The United States of America as represented by the United States Department of Agriculture
    Inventors: Nicholas G. Yeager, Kathleen C. Hayes
  • Publication number: 20090117247
    Abstract: A starch-lipid composite and related composition are described that enhance yield and sensory properties of low fat ground meat. Techniques are described herein for improving the taste and characteristics of ground meat and foods using such, by incorporation of the composite and/or the noted composition.
    Type: Application
    Filed: November 7, 2008
    Publication date: May 7, 2009
    Applicants: UNITED STATES DEPARTMENT OF AGRICULTURE, HERITAGE FARE, LTD.
    Inventors: Frederick C. Felker, George F. Fanta, Robert L. Kalebic, Wendell E. Turner
  • Publication number: 20070077636
    Abstract: A method of making a compound having the structural formula: wherein at least two of R1, R2, and R3 are non-fatty acid carboxylates, and the other of R1, R2, and R3 are each either a C2-C24 fatty acid moiety, OH, or a non-fatty acid carboxylate, wherein the first and second non-fatty acid carboxylates, when present, are the same or different, comprising (a) partially deacylating a triacylglycerol so as to provide a mono- or diacylglycerol, (b) reacting in a reaction mixture an acyl ester of the phytochemical with said mono- or diacylglycerol in the presence of a esterase catalyst under conditions that permit transesterification of said ester with said mono- or diacylglycerol, and (c) recovering said compound from said reaction mixture.
    Type: Application
    Filed: June 19, 2006
    Publication date: April 5, 2007
    Applicants: Biotechnology Research & Development Corporation, United States Department of Agriculture
    Inventors: Joseph Laszlo, David Compton, Louis DeFilippi, Steven Grall
  • Publication number: 20070077214
    Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an 0, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.
    Type: Application
    Filed: June 19, 2006
    Publication date: April 5, 2007
    Applicants: Biotechnology Research & Development Corporation, United States Department of Agriculture
    Inventors: Joseph Laszlo, David Compton, Louis DeFilippi, Steven Grall
  • Publication number: 20040248285
    Abstract: A fluorescent spectroscopic method and apparatus for real time direct detection of transmissible spongiform encephalopathies in central nervous system tissue by monitoring the fluorescence of intrinsic markers in the tissue by illuminating the tissue with UV or visible light having an appropriate wavelength, and the resulting emission spectra is detected and examined in the region from 350 to 650 nm. A higher intensity in this region is indicative of infected tissue. The apparatus and method would not interfere with existing slaughterhouse line speeds or procedures, and could be used on live animals.
    Type: Application
    Filed: August 8, 2003
    Publication date: December 9, 2004
    Applicants: eMerge Interactive, Inc., Iowa State University Research Foundation, Inc., United States Department of Agriculture
    Inventors: Thomas A. Casey, Mark A. Rasmussen, Albin H. Gapsch, Ricky Lee Flick, Jacob W. Petrich
  • Patent number: 6689397
    Abstract: Snake repellents include a repellent composition, an inert carrier and an adjuvant. The snake repellents include an essential oil selected from a group of essentials oils or a reagent from one of the essential oils. Methods of repelling snakes include exposing snakes to the snake repellents by aerosol, vapor or fog.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: February 10, 2004
    Assignee: The United States of America as represented by the United States Department of Agriculture
    Inventors: Larry Clark, John A. Shivik, Jr.
  • Patent number: 6296879
    Abstract: A method to improve the health and growth of suckling dairy calves on dairy farms includes supplementing calves' diets with a ruminal fluid preparation obtained from the rumen of a cow. This supplement provides the calves with the protection needed to develop faster and healthier. It also leads to a decreased incidence of scours in the treated calves.
    Type: Grant
    Filed: September 8, 1999
    Date of Patent: October 2, 2001
    Assignees: Cornell Research Foundation, Inc., The United States of America as represented by the United States Department of Agriculture
    Inventors: Thomas V. Muscato, James B. Russell
  • Patent number: 6156956
    Abstract: ACC synthases of higher plants are coded by multigene families; only certain members of these families are responsible for various plant development characteristics effected by ethylene. Control of the processes in plants which are mediated by ACC synthase, such as fruit ripening, can be effected by controlling expression of the relevant ACC synthase gene. In addition, comparison of the amino acid and nucleotide sequence of the ACC synthases from cucumber and tomato provides consensus sequences that permit the design of PCR primers that permit the isolation of ACC synthases from a variety of higher plants.
    Type: Grant
    Filed: March 2, 1998
    Date of Patent: December 5, 2000
    Assignee: The United States of America as represented by the United States Department of Agriculture
    Inventors: Athanasios Theologis, Takahido Sato
  • Patent number: 6060521
    Abstract: Aqueous dispersion of a particulate solid containing a low boiling organic liquid in which the particulate solid has a hydrophobic outer surface which is suitable for applying to a substrate to form a continuous hydrophobic film thereon.
    Type: Grant
    Filed: October 29, 1998
    Date of Patent: May 9, 2000
    Assignee: Engelhard Corporation United States Department of Agriculture
    Inventors: Dennis G. Sekutowski, Gary J. Puterka, David Michael Glenn
  • Patent number: 5996276
    Abstract: A method and aerodynamic transport body for delivering biological control agents into a field is provided. The aerodynamic transport body is a biodegradable device into which the biological control agent is placed and then the device is projected into the field using a catapult.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: December 7, 1999
    Assignee: The United States of America as represented by the United States Department of Agriculture
    Inventors: Lyle Marvin Carter, Joseph H. Chesson, John Victor Penner