Abstract: Provided are methods for lyophilization of an aqueous thrombin solution, thrombin solutions for use in such lyophilization methods, and solid thrombin compositions produced by such methods.
Type:
Grant
Filed:
December 9, 2021
Date of Patent:
May 28, 2024
Assignee:
Omrix Biopharmaceuticals Ltd.
Inventors:
Roberto Meidler, Oleg Belyaev, Liliana Bar, Israel Nur
Abstract: This invention relates generally to products and methods using lunasin-enriched soy extract combined with Reliv Now® to reduce free fatty acid levels and increase leptin levels and adiponectin levels in plasma for the control of obesity, type 2 diabetes and metabolic syndrome. More specifically, the present invention relates to novel compositions comprising lunasin enriched soy extract and Reliv Now® formulations, methods of using these compositions in individuals for the control of obesity, type 2 diabetes and metabolic syndrome, and methods of making compositions comprising them.
Type:
Grant
Filed:
July 7, 2021
Date of Patent:
May 21, 2024
Assignee:
SL Technology, Inc.
Inventors:
Alfredo Flores Galvez, Ryan Schmidt, Carl Hastings
Abstract: Aspects of the invention relate to compositions comprising one or more live bacterial strains for topical administration to the skin, wherein the one or more live bacterial strains are Propionibacterium acnes (P. acnes) bacterial strains, and methods for use.
Abstract: Compositions comprising Methylobacterium with anti-fungal activity, methods for controlling plant pathogenic fungi, and methods of making the compositions are provided.
Type:
Grant
Filed:
March 4, 2022
Date of Patent:
March 19, 2024
Assignee:
NewLeaf Symbiotics, Inc.
Inventors:
Renèe Rioux, Charles Michael McFatrich, Kishore Nannapaneni
Abstract: A quantitative detection method of rare earth doped calcium phosphate fluorescent nanoparticles (RE-nCaP) in organisms includes establishing a fluorescent intensity-concentration standard curve of rare earth ions, preparing samples to be tested and the blank control group into homogenate, performing centrifuging and testing the fluorescent intensity of supernatants, calculating the fluorescent intensity values per unit mass or volume of the samples and the blank control group, and performing significant difference analysis; if P is greater than or equal to 0.05, determining that the RE-nCaP content in the samples is 0, and if P is smaller than 0.05, testing the tissue extraction rate of RE-nCaP; and comprehensively considering the tissue extraction rate, the homogenate volume, the fluorescent intensity value per until mass or volume, the homogenate dilution ratio, and the doping amount to obtain the accurate content of the RE-nCaP in biological tissue samples.
Abstract: The disclosure provides a method of treating, preventing, and/or controlling plant diseases by applying the agricultural composition comprising a bacterial isolate belonging to Paenibacillus or Bacillus. Also, the disclosure provides a method of enhancing disease resistance of a plant seed by applying the agricultural composition to the plant seed, and an agricultural composition comprising the bacterial isolate.
Type:
Grant
Filed:
March 27, 2018
Date of Patent:
March 5, 2024
Assignee:
Tenfold Technologies, LLC
Inventors:
Shaohua Guan, Shashi Shankar Rajbanshi, Curtis Brian Hill
Abstract: Methods and solutions are disclosed for the quantification of mixed-linkage beta-glucan in plant biomass samples. Improved alkaline pretreatment, enzymatic hydrolysis, and glucose measurement parameters are provided that increase the accuracy, precision, and sensitivity of mixed-linkage beta-glucan assays.
Abstract: The present invention relates to compositions comprising Lactobacillus plantarum 2830 (ECGC 13110402), or mutant strain or strains thereof, for use in the treatment or prevention of hypertension.
Abstract: According to the present invention, organic material is converted to biogas through anaerobic digestion and the biogas is purified to yield a combustible fluid feedstock comprising methane. A fuel production facility utilizes or arranges to utilize combustible fluid feedstock to generate renewable hydrogen that is used to hydrogenate crude oil derived hydrocarbons in a process to make transportation or heating fuel. The renewable hydrogen is combined with crude oil derived hydrocarbons that have been desulfurized under conditions to hydrogenate the liquid hydrocarbon with the renewable hydrogen or alternatively, the renewable hydrogen can be added to a reactor operated so as to simultaneously desulfurize and hydrogenate the hydrocarbons. The present invention enables a party to receive a renewable fuel credit for the transportation or heating fuel.
Abstract: Methods of controlling agricultural pests are disclosed. An aerated liquid mixture is formed from a composition containing a bacterial nutrient source, a nitrogen-containing compound, a phosphate-containing compound, a magnesium-containing compound, a buffer, a chitinase inducer, and at least one strain of bacteria that produces chitinase. The liquid mixture is administered to soil and plants, and acts as an organic biological pesticide.
Abstract: In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.
Type:
Grant
Filed:
December 19, 2018
Date of Patent:
November 28, 2023
Assignee:
SELUX DIAGNOSTICS, INC.
Inventors:
Aleksandar Vacic, Nathan Purmort, Eric Stern, Anna Passernig, Paul Otten, Randy Tragni, Ronan Hayes, Andriy Tsupryk, Bruce Richardson
Abstract: An objective of the present invention is to provide a culturing method, by which Bacillus bacterial spores can be efficiently produced. The present invention provides a method for producing Bacillus bacterial spores, comprising culturing Bacillus bacteria in a liquid medium containing a sugar or a sugar-source raw material at a concentration between 50.1 g/L and 100 g/L at the start of culture, and then in the course of the culture, feeding a fed-batch medium containing a sugar or a sugar-source raw material and a nitrogen-containing compound, and having the weight ratio (C/N ratio) of carbon atoms to nitrogen atoms ranging from 5.5 to 13.5 to the liquid medium.
Abstract: The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.
Type:
Grant
Filed:
October 13, 2021
Date of Patent:
October 31, 2023
Assignee:
Novozymes A/S
Inventors:
Derrick Lewis, Marianne Thorup Cohn, Adam Nelson, Preben Nielsen
Abstract: Processes disclosed are capable of converting biomass into high-crystallinity, hydrophobic cellulose. In some variations, the process includes fractionating biomass with an acid (such as sulfur dioxide), a solvent (such as ethanol), and water, to generate cellulose-rich solids and a liquid containing hemicellulose and lignin; and depositing lignin onto cellulose fibers to produce lignin-coated cellulose materials (such as dissolving pulp). The crystallinity of the cellulose material may be 80% or higher, translating into good reinforcing properties for composites. Optionally, sugars derived from amorphous cellulose and hemicellulose may be separately fermented, such as to monomers for various polymers. These polymers may be combined with the hydrophobic cellulose to form completely renewable composites.
Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
Type:
Grant
Filed:
August 6, 2020
Date of Patent:
September 12, 2023
Assignees:
National University Corporation Asahikawa Medical University, Sapporo Holdings Limited
Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
Type:
Grant
Filed:
August 12, 2022
Date of Patent:
August 15, 2023
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: A method for growing probiotic organisms wherein the growth media includes prebiotics especially selected and prepared to be paired with the probiotic organisms being grown. The prebiotic formula is optimized to grow the desired probiotic organisms, as well as important byproducts of the growth process. Specialized freeze-drying buffers may also be paired with certain probiotic organisms for the freeze-drying process. Specific products may utilize selected probiotic organisms grown and supported with paired prebiotic formulas to promote and maintain physiological health in a subject.
Abstract: A method for producing an antimicrobial agent is provided. The method includes co-fermenting at least one seed of Lepidium Sativum and at least one yeast in a growth media to produce a yeast lees co-fermented by-product. The yeast lees by-product is then applied to a growth medium and at least one cell of Ganoderma Lucidum as a liquid medium under controlled conditions to produce mycelium and the liquid medium is agitated. The liquid medium is then filtered to isolate and extract an antimicrobial agent.
Type:
Grant
Filed:
November 2, 2020
Date of Patent:
August 8, 2023
Assignee:
Active Micro Technologies, LLC
Inventors:
Durant Scholz, Tiffany Russell, Erica Segura, Anna Crovetto, Maureen Danaher, Monica Beltran, Parisa Mehrzadeh
Abstract: A method for growing probiotic organisms wherein the growth media includes prebiotics especially selected and prepared to be paired with the probiotic organisms being grown. The prebiotic formula is optimized to grow the desired probiotic organisms, as well as important byproducts of the growth process. Specialized freeze-drying buffers may also be paired with certain probiotic organisms for the freeze-drying process.
Abstract: A method for determining whether a test sample contains a phytopathogenic fungus, which includes (a) putting the test sample on a front surface of a substrate having a through hole; the substrate having a cellulose film on the back surface thereof; the through hole has a cross-sectional area of not less than 7.065 square micrometers and not more than 19.625 square micrometers; and the cellulose film has a thickness of not less than 0.5 micrometers and not more than 3.7 micrometers; (b) leaving the test sample at rest after the step (a); (c) irradiating the cellulose film with ultraviolet light after the step (b); (d) bringing a back surface of the cellulose film into contact with a fungus color reaction reagent after the step (c); and (e) determining that the test sample contains the phytopathogenic fungus, if a color is given to the fungus color reaction reagent.