Patents Examined by Leigh C. Maier
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Patent number: 11851504Abstract: The invention relates to an iron oligosaccharide compound with improved stability comprising a hydrogenated oligosaccharide in stable association with ferric oxyhydroxide, the content of dimer saccharide in said hydrogenated oligosaccharide being 2.9% by weight or less, based on the total weight of the hydrogenated oligosaccharide. In further aspects is provided a process for preparing said compound as well as the use of said compound for preparation of a composition for treatment of iron deficiency anaemia.Type: GrantFiled: January 6, 2021Date of Patent: December 26, 2023Assignee: PHARMACOSMOS HOLDING A/SInventor: Hans Andreasen
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Patent number: 11840583Abstract: The present application relates to cellulose nanocrystals and other anionic carbohydrates and methods of preparation thereof. Specifically, in certain embodiments, the cellulose nanocrystals are modified using ion exchange technology to yield thermally stable or task-specific, dispersible cellulose nanocrystals.Type: GrantFiled: April 22, 2021Date of Patent: December 12, 2023Assignee: AMERICAN UNIVERSITYInventor: Douglas Fox
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Patent number: 11840584Abstract: The present disclosure discloses a simple preparation method of green acid-modified cyclodextrin, belonging to the field of cyclodextrin modification. Cyclodextrin and succinic acid are mutually modified by an esterification reaction in the presence of catalyst, and acid-modified cyclodextrin with different modification degrees is obtained by controlling reaction time at a high temperature or under a microwave action. The prepared modified cyclodextrin does not involve the use of toxic and harmful reagents, the modification reaction is simple, green and controllable, and the loading capacity of the modified cyclodextrin to guest molecules is remarkably improved compared with the loading capacity of the original cyclodextrin, so that the modified cyclodextrin has great application potential in the health fields such as food, medicines, and cosmetics.Type: GrantFiled: March 16, 2023Date of Patent: December 12, 2023Assignee: JIANGNAN UNIVERSITYInventors: Chao Qiu, Jinpeng Wang, Yao Hu, Zhengyu Jin, Qianzhu Lin, Yaoqi Tian, Aiquan Jiao, Long Chen, Zhengjun Xie, Xing Zhou
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Patent number: 11833450Abstract: A method of recovering a bead support from an emulsion includes supplying an aqueous surfactant solution into a centrifuge tube; supplying a hydrophobic liquid over the surfactant solution in the centrifuge tube, wherein a ratio of the volume of the aqueous surfactant solution to the volume of the hydrophobic liquid is not greater than 0.5; and applying an emulsion over the hydrophobic liquid while centrifuging, the emulsion comprising a dispersed aqueous phase including the bead support, the emulsion breaking and material of the dispersed phase preferentially partitioning to the surfactant solution.Type: GrantFiled: December 30, 2021Date of Patent: December 5, 2023Assignee: Life Technologies CorporationInventors: Brian Reed, James A. Ball
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Patent number: 11834560Abstract: The present invention relates to a water degradable film comprising hyaluronic acid or a salt thereof and polyphenol compounds. The film of the present invention can transcribe nanofilms in the form of CNT (carbon nanotube), graphene and magnetic particles to various places. The film of the present invention can be dissolved by an aqueous solution or body fluid, and can be effectively used in the medical field since it is non-toxic and biocompatible. The film of the present invention can also be effectively used as a transcript that does not degrade the quality and performance of the device because no residue remains in the electronic device and the existing photolithography process.Type: GrantFiled: July 21, 2020Date of Patent: December 5, 2023Assignee: Korea Research Institute of Chemical TechnologyInventors: Jae-Hyeok Lee, Sun-Hyun Park, Ki-Suk Kim
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Patent number: 11813241Abstract: Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of taxane-based compounds and/or fluorinated forms thereof. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the taxane-based compound is achieved.Type: GrantFiled: September 7, 2018Date of Patent: November 14, 2023Assignee: Nektar TherapeuticsInventors: Antoni Kozlowski, Timothy A. Riley, Samuel P. McManus
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Patent number: 11813350Abstract: The invention relates to a composition comprising, as dermatological active principle, at least one polysaccharide consisting of a glucose and trehalose heteropolymer and a branched hydrogenated glucose homopolymer comprising ? (1-4) and ? (1-6) bonds), for use in the treatment of rosacea and/or telangiectasia.Type: GrantFiled: November 8, 2021Date of Patent: November 14, 2023Assignees: NAOS INSTITUTE OF LIFE SCIENCEInventor: Jean-Noël Thorel
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Patent number: 11802169Abstract: The invention proposes a method of separating hemicellulose through efficient pretreatment of fibrous biomass materials. Fibrous biomass materials are first pretreated by the slurry method: the fibrous biomass materials are milled through ball mills and sieved to obtain fibrous biomass material powder, and the powder is mixed with water at room temperature to obtain slurry premixed solution of the fibrous biomass material powder. Through regulation and control of the reaction temperature, the time and the water amount, efficient hydrothermal removal of hemicellulose from the fibrous biomass material powder is realized. After the mixed solution is filtered, the filtrate is subject to gradient sedimentation to separate hemicellulose with low dispersity, and the sediment is then dried before storage. After the filter residue is mixed with polar aprotic solvent and water, and heated and stirred in a pressurized reactor, high-purity cellulose is obtained through filtering and separation.Type: GrantFiled: August 16, 2019Date of Patent: October 31, 2023Assignee: INSTITUTE OF CHEMICAL INDUSTRY OF FOREST PRODUCTS, CAFInventors: Kui Wang, Jianchun Jiang, Yanyan Liu, Junming Xu, Min Wei, Linshan Wei, Ruizhen Wang
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Patent number: 11801310Abstract: A composition for improving the solubility of poorly soluble substances is provided. The composition includes about 40-99.5% by weight of cyclodextrin and/or derivatives thereof; about 0.05-10% by weight of at least one water-soluble polymer; and about 0.05-60% by weight of at least one water-soluble stabilizer.Type: GrantFiled: December 26, 2018Date of Patent: October 31, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wen-Chia Huang, Yen-Jen Wang, Felice Cheng, Chia-Ching Chen, Shao-Chan Yin, Chien-Lin Pan, Tsan-Lin Hu, Meng-Nan Lin, Kuo-Kuei Huang, Maggie Lu, Chih-Peng Liu
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Patent number: 11802166Abstract: An object of the present disclosure is to provide a cellulose acetate film having excellent bending properties and high transparency. The subject cellulose acetate film contains cellulose acetate having a cellulose triacetate I crystal structure, the cellulose acetate film having a light transmittance of 70% or higher at 660 nm.Type: GrantFiled: February 26, 2020Date of Patent: October 31, 2023Assignees: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, DAICEL CORPORATIONInventors: Yasumitsu Uraki, Haruo Konno, Shu Shimamoto
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Patent number: 11795241Abstract: The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.Type: GrantFiled: November 24, 2020Date of Patent: October 24, 2023Assignee: CyDex Pharmaceuticals, Inc.Inventors: Vincent D. Antle, Charles Alan Watson, David W. Miles
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Patent number: 11779594Abstract: The present invention concerns the field of medications for the treatment of lesions and wounds of the skin and mucosa. The present invention relates to the use of a composition comprising a combination of a mucoadhesive component in the range from 0.05-20% by weight, an emollient component in the range from 0.02-20% by weight, hydrating and mucoprotective component i.e. hyaluronic acid in the range from 0.01-15% by weight and epithelizing component i.e. one or more amino acids in the range from 0.02-5% by weight in the treatment of epithelial lesions. The invention further comprises a composition comprising: —carbomer (poly acrylic acid) in the range from 0.05% to 5%; —sodium hyaluronate in the range from 0.01% to 15%; —poloxamer (copolymers of ethylene oxide and propylene oxide) in the range from 0.1% to 15%; —Oryza sativa extract in the range from 0.2% to 20%; and —one or more amino acids in the range from 0.025% to 5%, wherein said percentages are by weight of the total weight of the product (w/w).Type: GrantFiled: October 22, 2020Date of Patent: October 10, 2023Assignee: INTERNATIONAL HEALTH SCIENCE S.R.L.Inventor: Carlo Terruzzi
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Patent number: 11779593Abstract: Provided is an agent for improving human ocular subjective symptoms containing hyaluronic acid having an aminoalkyl cinnamate covalently bonded thereto.Type: GrantFiled: October 25, 2021Date of Patent: October 10, 2023Assignee: SEIKAGAKU CORPORATIONInventors: Masamichi Yamada, Chiyo Sakenaga, Keiichiro Arai, Kazutaka Yamamoto
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Patent number: 11773239Abstract: The purpose of the present invention is to provide a cellulose acetate excellent in transparency, and a molded article of the cellulose acetate. In the cellulose acetate, an acetylation degree is 52% or more and 59% or less, and a content of low-molecular-weight components having a molecular weight of not more than ¼ of a peak top molecular weight in a molecular weight distribution measured by gel permeation chromatography of cellulose acetate is 12% or less.Type: GrantFiled: January 17, 2018Date of Patent: October 3, 2023Assignee: DAICEL CORPORATIONInventors: Ikuhiro Suzuki, Yuya Ashida, Akihiro Higuchi
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Patent number: 11773188Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: GrantFiled: August 9, 2021Date of Patent: October 3, 2023Assignee: Immunophotonics, IncInventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Patent number: 11760812Abstract: The method for producing medium viscosity carboxymethyl cellulose from date palm fronds includes drying date palm fronds, grinding the dried date palm fronds to a powder, mixing the powder with an alkaline solution to a provide a slurry, isolating a cellulose extract from the slurry, drying the cellulose extract, grinding the dried cellulose extract to a powder, adding isopropanol to the powder to provide a mixture, adding an alkaline solution to the mixture to provide an alkaline mixture, and adding a mixture of monochloroacetic acid and trichloroacetic acid to the alkaline mixture to provide carboxymethyl cellulose (CMC) as an alkaline salt thereof. The CMC can be used for cultivating desert land while saving water.Type: GrantFiled: January 12, 2023Date of Patent: September 19, 2023Assignee: KING FAISAL UNIVERSITYInventors: Ahmed Bin Saud Al-Saqoufi, Abdul Rahman Bin Mohammad Al-Madini, Nabil Bin Saud Al Balushi, Mohammad Bin Rafdan Hassan Al-Hajhoj, Mohamed Soliman Shathele, Ahmed Meligy Abdelghany Meligy, Mohammed Mohammed Mahmoud Elgarawany
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Patent number: 11760811Abstract: A carboxymethylated cellulose having a carboxymethyl substitution of no more than 0.50 and a cellulose I type crystallization of at least 50%. Ideally, the anionization is 0.00-1.00 meq/g. The Schopper-Riegler freeness is ideally at least 60.0° SR. Ideally the ratio of filtration residue is 0%-30% by mass. The viscosity (30 rpm, 25° C.) for an aqueous dispersion having a 1% solid content (w/v) is ideally no more than 10.0 mPa·s.Type: GrantFiled: December 5, 2018Date of Patent: September 19, 2023Assignee: NIPPON PAPER INDUSTRIES CO., LTD.Inventors: Kazuhiko Inoue, Takeshi Nakatani, Yusuke Tada, Kasumi Nishigaya, Hiroyoshi Suzuki
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Patent number: 11752169Abstract: The present disclosure relates to the medical use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions. In particular, the disclosure relates to use of polysulfated polysaccharides and compositions thereof for the treatment of pain or pain conditions mediated by mature Nerve Growth Factor (NGF) or its precursor pro-Nerve Growth Factor (pro-NGF).Type: GrantFiled: October 10, 2019Date of Patent: September 12, 2023Assignee: PARADIGM BIOPHARMACEUTICALS LTD.Inventors: Paul Rennie, Ravi Krishnan
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Patent number: 11744899Abstract: Provided is a method for suppressing the generation of diclofenac lactam from a compound represented by a formula (1) in the description, including allowing the compound of the formula (1) and a component (A) that is at least one type of compound selected from the group consisting of a nonionic surfactant, a hydroxyalkylated cyclodextrin, a C1 to C3 mono-alcohol, a C2 to C3 di-alcohol, a C3 to C6 tri-alcohol, a polyalkylene glycol, a ?-lactone, polyvinylpyrrolidone, a chlorogenic acid, and an alkyl sulfate ester, and salts thereof to coexist. A method for producing a pharmaceutical composition containing a compound represented by the formula (1) and a component (A), and a pharmaceutical composition which is a product produced thereby are also provided.Type: GrantFiled: November 15, 2019Date of Patent: September 5, 2023Assignee: SEIKAGAKU CORPORATIONInventors: Chiaki Takahata, Naoya Yamashita, Naoko Kunii, Hirotaka Hoshi
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Patent number: 11730179Abstract: A method of processing an initial starch containing gluten protein to produce a purified starch having less than 20 parts per million of a gluten protein (i.e., “gluten free”). A slurry of the unpurified starch is treated with an agent to degrade the gluten protein, and then the degraded gluten protein is removed, resulting in a slurry of the purified starch. The slurry of the purified starch is dried, resulting in the purified starch, and the purified starch is tested to confirm that the purified starch meets the standard for being gluten free. The starch is from a member of the tribe Triticeae (e.g., wheat, rye, barley, or triticale) or other plant starch that either naturally contains gluten protein or may be contaminated with gluten protein. The agent is selected from among acids, bases, alcohols, surfactants, proteases, chaotropic agents, reducing agents, and combinations thereof.Type: GrantFiled: June 27, 2016Date of Patent: August 22, 2023Assignee: Manildra Milling CorporationInventor: Neal Dev Bassi