Abstract: A surgical system includes at least one light emitter and an array of light sensors disposed at the working end of the surgical instrument, individual light sensors in the array of light sensors adapted to generate a signal comprising a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer configured to determine a curve of the non-pulsatile components of the signals of each of the individual light sensors in the array of light sensors, smooth the curve, calculate a derivative of the smoothed curve; invert the smoothed curve, calculate a derivative of the inverted smoothed curve, take a difference between the derivatives, smooth the resultant curve, estimate zero crossings of the smoothed, resultant curve, apply a signum function to points adjacent each zero crossing, if any, and identify a region of interest, if any, based on the result.

Abstract: An anti-contamination laser surgery device with a built-in optical element, including an inner cylinder, an outer cylinder, a first unit configured to enable the inner cylinder and the outer cylinder to be telescopic, a lens moving unit, a two-dimensional laser scanning unit, a real-time monitoring unit, and a second unit configured to perform unidirectional laminar flow ventilation. A head end of the inner cylinder and a tail end of the outer cylinder are matched and connected by the first unit. The two-dimensional laser scanning unit and the real-time monitoring unit are arranged at the head end of the outer cylinder, and the lens moving unit is arranged in the inner cylinder and close to the head end of the inner cylinder. The second unit is arranged close to a tail end of the inner cylinder.

Abstract: Methods and devices for tying management of an implantable medical device to the activities of a primary care physician are described, including access control, simplified parameter optimization, support for tuning a device in response to the effects of other treatments in parallel, and support for helping a primary physician and a patient work together to tune device configuration to the activity and performance needs of the patient. In some embodiments, a medical device is self-configuring in a device parameter domain, based on inputs provided in a patient performance domain. The self-configuring of the medical device is based, for example, on an automatically applied transformation of inputs derived from patient performance domain observations into changes in the configuration of the medical device which affect technical parameters of its operation.

Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.

Abstract: Systems and Methods are disclosed for detecting acute coronary syndrome (ACS) events, arrythmias, heart rate abnormalities, medication problems such as non-compliance or ineffective amount or type of medication, and demand/supply related cardiac ischemia. The system may have both implanted and external components that communicate with a Physicians's programmer, and smart-devices for monitoring and alerting to detected medically relevant events or states. At least one processor provides event detection using statistical threshold criteria calculated upon at least a portion of a patient's data/distributions and set for a patient or based upon what a doctor determines as abnormal for a patient. Cardiovascular condition is tracked using histogram, trend, and summary information related to heart rate and/or cardiac features such as S-T segment measures of heartbeats.

Abstract: A wearable external defibrillator with a plurality of ECG sensing electrodes and a first defibrillator pad electrode and a second defibrillator pad electrode. The ECG sensing electrodes and the defibrillator pad electrodes are configured for long term wear.

Abstract: The present disclosure provides methods for identifying non-penetrating brain injury in a subject, as well as methods for classifying a subject that received a hit to the body that transmitted an impulsive force to the brain as either having a non-penetrating brain injury or not, by analyzing one or more components of frequency-following response (FFR) following administration of an acoustic stimulus to the subject. In addition, the present disclosure provides methods for assessing a subject's recovery from a non-penetrating brain injury. Also disclosed herein are processes and systems for automatically generating acoustic stimuli and processing brain response data to identify non-penetrating brain injuries in subjects.

Abstract: A system is provided for displaying heart graphic information relating to sources and source locations of a heart disorder to assist in evaluation of the heart disorder. A heart graphic display system provides an intra-cardiogram similarity (“ICS”) graphic and a source location (“SL”) graphic. The ICS graphic includes a grid with the x-axis and y-axis representing patient cycles of a patient cardiogram with the intersections of the patient cycle identifiers indicating similarity between the patient cycles. The SL graphic provides a representation of a heart with source locations indicated. The source locations are identified based on similarity of a patient cycle to library cycles of a library cardiogram of a library of cardiograms.

Abstract: Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having a spinal cord injury, a brain injury, or a neurological neuromotor disease are described.

Abstract: A sensor device comprises at least two sensors at the end of a shaft (such as a guidewire or catheter). One sensor uses signals in a first frequency range and a first voltage range and the other sensor uses signals in a second frequency range different to the first frequency range and a second voltage range different to the first voltage range. The first sensor is shorted based on frequency analysis, thereby to prevent the first sensor being exposed to signals associated with the second sensor. This enables the two sensors to be driven by the same shared pair of wires along the shaft, with automatic selection of the suitable sensor.

Abstract: Systems and methods for improved user experience with rechargers for implantable medical devices. An external charging device for providing power to a rechargeable implantable device can determine a firmware state of the external charging device during recharging of the rechargeable implantable device, display a searching indication using a light indicator when the firmware state is determined to be in a searching state, display a charging indication using the light indicator when the firmware state is determined to be a charging state, and display an error indication using the light indicator when the firmware state is determined to be an error state. An optional user device application can provide complementary graphical user interfaces according to the firmware states.

Abstract: A system for reading bioelectrical signals from the skin of a user is provided. The system comprises a plug for inserting in an ear having an inner portion to be inserted into the ear, an outer portion and an inner floating electrode comprising a floating conductive wire, the floating conductive wire being attached to the inner portion of the plug, disposed over the outskirt of the outer portion and in communication with the signal processor. The system further comprises an outer floating electrode for reading a signal from skin around the ear, the floating electrode comprising a floating conductive portion connected to the plug and being in communication with the signal processor, a resilient portion adapted to expand and retract the floating conductive portion and a non-conductive linking portion attached to the floating conductive portion. The floating, resilient and non-conductive linking portions form an expandable loop around the ear from the plug.

Abstract: The present invention relates to a non-invasive cardiac monitoring device that records cardiac data to infer physiological characteristics of a human, such as cardiac arrhythmia. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments allow for processing of the detected cardiac rhythm signals partially on the wearable cardiac monitor device, and partially on a remote computing system. Some embodiments include a wearable cardiac monitor device for long-term adhesion to a mammal for prolonged detection of cardiac rhythm signals.

Abstract: Disclosed is a device for providing resuscitation or suspended state through redistribution of cardiac output to increase supply to the brain and heart for a patient. The device includes an electrically controllable redistribution component attachable to the patient to provide redistribution of the cardiac output to increase supply to the brain and heart. The redistribution component, following a predefined reaction pattern based on an electrical signal, and computer means configured to: receive a patient data which identifies physiological and/or anatomical characteristics of the patent; and provide the electrical signal for the redistribution component based on the patient data or a standard response. The device may provide mechanisms to protect the aorta and the remaining anatomy of the patient from inadvertent damage caused by the disclosed device in any usage scenario of either correct intended usage or unintended usage. Also disclosed is a method for providing resuscitation or suspended state.

Abstract: Disclosed herein are systems and methods for nerve conduction block. The systems and methods can utilize at least one renewable electrode. The methods can include delivering a first direct current with a first polarity to an electrode proximate nervous tissue sufficient to block conduction in the nervous tissue. Delivering the first direct current can place the nervous tissue in a hypersuppressed state at least partially preventing conduction of the nervous tissue after cessation of delivering of the first direct current. The nervous tissue can be maintained in the hypersuppressed state for a desired period, such as at least about 1 minute.

Abstract: An implantable medical system includes at least four electrodes forming a dipole emitter and a dipole receiver which is distinct from the dipole emitter. The system is configured to recover physiological mechanical information by way of the two dipoles, by analyzing a received and processed electrical signal, wherein the amplitude has been modulated in accordance with the electrical properties of the propagation medium between the dipole emitter and the dipole receiver. Thus, a parameter which is representative of a pre-ejection period may be extracted from the attenuation of the voltage between the dipole emitter and the dipole receiver by taking an electrocardiogram or an electrogram into account.

Abstract: An electrode for neural sensing and stimulation comprising a first electrode disposed on a probe and a second electrode disposed on the probe, wherein a voltage or impedance is sensed using the first electrode and second electrode.

Abstract: Methods and apparatuses are described herein for treating a patient with mild cognitive impairment (MCI) or dementia by one or more digital therapeutics. For example, a patient. who has been diagnosed with the MCI or dementia may administer one or more digital therapeutics to the patient to improve a plurality of neurohumoral factors that cause the MCI or the dementia of the patient. The digital therapeutics may include one or more digital instructions that are generated to treat at least one imbalance of the plurality of neurohumoral factors based on at least one neurohumoral change among the plurality of neurohumoral factors by the patient's performance of the one or more digital instructions. The one or more digital instructions may include at least one of an execution environment setting, a lifestyle change, learning, exercising, or affirmation/achievement task.

Abstract: Systems, devices, methods, and techniques are described for using evoked compound action potential (ECAP) signals to determine an implant location for a lead. An example method includes receiving first information representative of a first evoked compound action potential (ECAP) signal sensed in response to a first control stimulus delivered to a first location adjacent to a spinal cord of a patient. The method also includes receiving, second information representative of a second ECAP signal in response to a second control stimulus delivered to a second location adjacent to the spinal cord of the patient. Additionally, the method includes outputting a first indication of the first information representative of the first ECAP signal and a second indication of the second information representative of the second ECAP signal.

Abstract: A device for assisting a caregiver in delivering cardiac resuscitation to a patient, the device comprising a user interface configured to deliver prompts to a caregiver to assist the caregiver in delivering cardiac resuscitation to a patient; at least one sensor configured to detect the caregiver's progress in delivering the cardiac resuscitation, wherein the sensor is configured to provide a signal containing information indicative of ventilation; a memory in which a plurality of different prompts are stored, including at least one ventilation progress prompt to guide the rescuer's performance of ventilation; a processor configured to process the output of the sensor to determine a parameter descriptive of ventilation progress and to determine whether the ventilation progress prompt should be selected for delivery. Possible parameters descriptive of ventilation progress include ventilation rate, delivered tidal volume, and flow rate.