Patents Examined by Subhaker R. Patel
  • Bicyclic amino acids
    Patent number: 6559144
    Abstract: Compounds of the formula I in which X, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m and n have the meanings stated in claim 1, and their physiologically acceptable salts can be used as integrin inhibitors, in particular for the prophylaxis and treatment of circulatory disorders, for thrombosis, myocardial infarct, coronary heart disease, arteriosclerosis, osteoporosis, for pathological processes maintained or propagated by angiogenesis, and in tumour therapy.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: May 6, 2003
    Assignee: Merck Patent Gesellschaft Mit
    Inventors: Beate Diefenbach, Simon L. Goodman, Joachim März, Peter Raddatz, Friedrich Rippmann, Matthias Wiesner