Abstract: Ablation systems and methods of the present disclosure control lesion depth and width such that, for example, wide and shallow lesions can be formed in target tissue in an anatomic structure of a patient during a medical procedure. Such wide and shallow lesions can be useful for treating, for example, thin tissue such as atrial tissue in atria of the heart of the patient.

Abstract: Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

Abstract: A pad for treating a perineal area of a woman before or after childbirth includes a foam layer and a substance integrated with the foam layer. The foam layer is flexible, so that it can conform to the perineal area of the woman. The pad may optionally include a skin contact layer made of an impermeable material. The foam layer and/or the optional skin contact layer may include openings, such as perforations or slits. A method of using the pad may involve placing the pad in the perineal area before or after childbirth. The pad may be frozen, cooled or heated before use, in different embodiments.

Abstract: The invention provides a cooling pad 110 for alleviation of pain or discomfort, especially in the perineum as a result of childbirth. The pad 110 has at least one chamber 116 containing a fluid (such as saline) for cooling. There is at least one aperture 126 for allowing passage of body fluid. The aperture 126 is located inboard of the chamber 116. Aperture 126 is formed in a web 124. Cooling pad 110 may be used alone or as part of an assembly, sandwiched between cover layer 130 and peel-off backing 132, and is intended to be placed in a freezer prior to use.

Abstract: The present disclosure concerns hyperthermic devices for treating vascular involvements related to cancer therapies, such as surgery. In specific embodiments, the device is configured to provide therapeutic heating to destroy vessel-encasing tumors while still protecting the vessel itself. In particular embodiments, the devices utilize two opposing semi-cylindrical shells that encase the vessel in need of treatment of a tumor thereon. In other devices, a flexible substrate is guided under and around the vessel and tumor thereon.

Abstract: An integrated gas-enhanced electrosurgical generator. The generator comprises a high frequency power module, a low frequency power module and a gas module. The high frequency power module adapted to generate an electrical energy having a band of frequencies centered around a first frequency, wherein the electrical energy has a first power as the first frequency and a second power lower than the first power at a second frequency lower than the first frequency. The low frequency power module having an input connected to an output of the high frequency module. The low frequency module comprises a resonant transformer comprising a ferrite core, a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, wherein the resonant transformer has a resonant frequency equal to the second frequency. The gas module is adapted to control a flow of an inert gas.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: It is an object of the present invention to provide a chemical body warmer that achieves a sufficient heating effect even in a low-temperature environment at about 10° C. or less. A chemical body warmer including a flat housing including one or a plurality of cells each containing an exothermic composition that generates heat upon contact with air, wherein a total area of the cell or the plurality of cells in a plan view of the housing is 200 cm2 or more, and the chemical body warmer is used by being placed under a blanket.

Abstract: An electrosurgical device comprises an electrically conductive elongate member for traversing body vasculature defining a hollow lumen with one or more apertures at or near its distal end, wherein electrical energy can flow through the wall of the elongate member; and an energy delivery device in electrical communication with the elongate member is located distal to the end of the elongate member. The energy delivery device includes an electrode for delivering energy. Methods of using the electrosurgical device include cutting through occlusions and creating transseptal punctures.

Abstract: An ablation catheter configured to ablate tissue in a lung of a patient including: a flexible shaft that advances endobronchially into an airway of the lung and has an outer diameter of 2.0 mm or less; an ablation electrode attached to a distal portion of the flexible shaft and to deliver radiofrequency (RF) electrical current to the tissue and conductively connectable to an RF electrical energy source external to the patient; wherein an outer diameter of an assembly of the flexible shaft and the ablation electrode is no greater than 2.0 mm; a liquid outlet on the distal portion and configured to be in fluid communication with a source of hypertonic saline solution; and a first occluder attached to the flexible shaft proximal to the ablation electrode and proximal to the liquid outlet, wherein the first occluder is configured to expand to occlude the airway.

Abstract: An air hose includes a corrugated flexible hose. The air hose also includes a first hose end section mechanically coupled to the corrugated flexible hose. The first hose end section includes a pressure sensor communicatively coupled to a warming unit. The first hose end section is configured to releasably couple to a pneumatic convective device. The air hose also includes a second hose end section mechanically coupled to the corrugated flexible hose. The second hose end section is configured to couple to the warming unit.

Abstract: A thermal control unit supplies temperature controlled fluid to one or more thermal pads used to control the temperature of a patient. The thermal control unit includes a fluid outlet, fluid inlet, heat exchanger, pump, and a controller. The controller receives first and second data from at least two different sources to determine if the patient is shivering or not. The two different sources may include a temperature sensor adapted to detect a temperature of the fluid, a temperature sensor adapted to detect a temperature of the patient, a tissue oxygenation sensor, a vibration/motion sensor, a thermal image sensor, an electromyograph, and/or other sensors. In some embodiments, the thermal control unit takes one or more automatic actions in response to detection of patient shivering.

Abstract: A vapor delivery needle is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, denaturate the prostate. In some embodiments, the vapor delivery needle can be advanced a predetermined distance into the prostate with a solenoid actuation mechanism. Methods associated with use of the energy delivery probe are also covered.

Abstract: Apparatuses and methods of fabrication are provided which include a mechanical coolant pump to facilitate pumping a coolant through a coolant loop. The mechanical coolant pump is to couple to an individual and be physically powered by a specified movement of the individual to pump coolant. Coolant pumped by the mechanical coolant pump is circulated by the coolant pump through a device associated with the individual to cool the device.

Abstract: A method of preparing cryogenic air for use in cryotherapy procedures, using liquid nitrogen and gaseous oxygen, characterized in that liquid nitrogen (1) is fed from a cryogenic nitrogen tank (2) via a cryogenic duct (3) to a reactor (4), wherein simultaneously a gas (7) containing oxygen in a concentration from 20% to 100% is fed from an oxygen source (5) to the reactor (4), through a gas duct (6), then, in the reactor (4), the liquid nitrogen (1) is evaporated using the gas (7) and both these components are mixed together, forming a cold breathable mixture (8), cooled to a set temperature of minus 80° C. to minus 160° C., which is further fed through a cold duct (9) terminated with an outlet (10) to a cryochamber (11).

Abstract: Systems and methods for measuring the magnetic fields generated by renal nerves before and/or after neuromodulation therapy are disclosed herein. One method for measuring the magnetic field of target nerves during a neuromodulation procedure includes positioning a neuromodulation catheter at a target site within a renal blood vessel of a human patient near the target nerves, and detecting a measurement of the magnetic field generated by the target nerves. The method can further include determining, based on the measurement of the magnetic field, a location of the target nerves, a location of ablation at the target nerves, and/or a percentage the target nerves were ablated by delivered neuromodulation energy.

Abstract: A package comprises a mask; and an inactive heater, wherein the mask includes at least one product layer having infused thereon at least one active, and wherein the inactive heater is located in or in proximity to the mask to transfer heat to the mask upon activation of the heater.

Abstract: Medical devices for sympathetic nerve modulation are disclosed. An example medical device for sympathetic nerve modulation may include a catheter shaft having a distal region. An expandable member may be coupled to the distal region. A flexible circuit assembly may be attached to the expandable member. The flexible circuit assembly may include a first electrode strip, a second electrode strip, and a sensor strip disposed between the first electrode strip and the second electrode strip. The first electrode strip may include a first electrode. The second electrode strip may include a second electrode. The first electrode and the second electrode may define a pair of bipolar electrodes.

Abstract: A plurality of control-signal generators are configured to generate respective control signals having respective control-signal amplitudes and different respective control-signal frequencies, and a plurality of signal adders are configured to produce respective composite signals for application to a subject, by adding the control signals to respective ablation signals having respective ablation-signal amplitudes. The control-signal generators are configured to generate the control signals such that respective ratios between the control-signal amplitudes and the ablation-signal amplitudes are constant during the application of the composite signals to the subject.

Abstract: The present disclosure relates to devices, systems and methods providing evaluation and feedback to an operator of a device providing neuromodulation treatment, such as modulation of renal nerves of a human patient. In one embodiment, for example, a system monitors parameters or values generated before treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of various electrical properties associated with an electrode carried by a catheter. The electrode measures an electrical property of biological material making contact with the electrode while deploying the electrode, the electrical property being dependent on a ratio of a wall-interface area to a fluid-interface area.