Patents by Inventor Alain Corbier

Alain Corbier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7005417
    Abstract: A subject of the invention is the compounds of formula (I): in which either R1 and R2=H, OH, alkyl optionally substituted, or NR1 form with the carbon carrying NR1R2 a double bond and R2 is XRa, X being O, NH OR N-alkyl and Ra being H, alkyl optionally substituted, or R2 is e-N?C(—N-d)-N(f)-g R3=H, OH, CH3 R4=H, OH R=chain containing up to 30 carbon atoms, optionally containing one or more heteroatoms, one or more heterocycles, T=H, CH3, CH2CONH2, CH2C?N, (CH2)2NH2, (CH2)2Nalk+X? Y=H, OH, Halogen, OSO3H W=H, OH Z=H or CH3. The products have of the antifungal properties.
    Type: Grant
    Filed: June 8, 2000
    Date of Patent: February 28, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Alain Corbier, Patrick Fauveau, Nathalie Pietre-Dischamp, Laurent Schio, Pascale Vicat
  • Patent number: 5977155
    Abstract: Products of formula (1), wherein R.sub.1 is particularly ##STR1## alkyl, alkylthio or alkoxy; R.sub.2 is particularly halogen, --S--R, --O--R or --C(OH)(R)--COOH, where R is alkyl or alkenyl; R.sub.3 is particularly carboxy, acyl, halogen, alkyl, alkenyl or alkylthio; and R.sub.4 is particularly --(CH.sub.2).sub.m1 --COOR.sub.4, --(CH.sub.2).sub.m1 --CONHR.sub.14, --(CH.sub.2).sub.m1 --CN, --SO.sub.2 --NH--SO.sub.2 --R.sub.14, 13 NH--SO.sub.2 --R.sub.14, --PO.sub.3 R.sub.14, or --NH--SO.sub.2 --CF.sub.3, where m1 is 0-4 and R.sub.14 is hydrogen, alkyl or alkenyl; are useful for preparing pharmaceutical compositions for treating disorders resulting from abnormal stimulation of angiotensin II receptors AT.sub.1 and AT.sub.2.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: November 2, 1999
    Assignee: Hoechst Marion Roussel
    Inventors: Alain Corbier, Pierre Deprez, Michel Fortin, Jacques Guillaume, Bertrand Heckmann
  • Patent number: 5811445
    Abstract: Products of formula (1), wherein R.sub.1 is particularly ##STR1## alkyl, alkylthio or alkoxy; R.sub.2 is particularly halogen, --S--R, --O--R or --C(OH)(R)--COOH, where R is alkyl or alkenyl; R.sub.3 is particularly carboxy, acyl, halogen, alkyl, alkenyl or alkylthio; and R.sub.4 is particularly --(CH.sub.2).sub.m1 --COOR.sub.4, --(CH.sub.2).sub.m1 --CONHR.sub.14, --(CH.sub.2).sub.m1 --CN, --SO.sub.2 --NH--SO.sub.2 --R.sub.14, 13 NH--SO.sub.2 --R.sub.14, --PO.sub.3 R.sub.14, or --NH--SO.sub.2 --CF.sub.3, where m1 is 0-4 and R.sub.14 is hydrogen, alkyl or alkenyl; are useful for preparing pharmaceutical compositions for treating disorders resulting from abnormal stimulation of angiotensin II receptors AT.sub.1 and AT.sub.2.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: September 22, 1998
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Pierre DePrez, Michel Fortin, Jacques Guillaume
  • Patent number: 5807878
    Abstract: A compound of the formula ##STR1## wherein the substituents are defined in the specification useful for the treatment of cardiovascular disorders.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: September 15, 1998
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Pierre Deprez, Michel Fortin, Jacques Guillaume, Bertrand Heckmann
  • Patent number: 5714508
    Abstract: Described herein are compounds of the formula ##STR1## wherein the substituents are defined as in the specification having inhibiting activity on the effects of angiotensin II.
    Type: Grant
    Filed: August 1, 1994
    Date of Patent: February 3, 1998
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Jean Paul Vevert, Jidong Zhang
  • Patent number: 5691347
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: April 20, 1995
    Date of Patent: November 25, 1997
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5684028
    Abstract: Novel compounds of the formula ##STR1## wherein the, substituents are defined as in the specification and their non-toxic, pharmaceutically acceptable salts which inhibit the effects of angiotensin II in warm-blooded animals.
    Type: Grant
    Filed: October 9, 1996
    Date of Patent: November 4, 1997
    Assignee: Roussel UCLAF
    Inventors: Jean Claude Caille, Alain Corbier, Michel Fortin, Gilles Hamon, Simone Jouquey, Jean Paul Vevert
  • Patent number: 5650414
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: July 22, 1997
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5599830
    Abstract: The invention relates to the products: ##STR1## in which: R.sub.1 =alkyl, alkenyl, alkynyl, alkylthio,R.sub.2B, R.sub.3B representing:hydrogen, mercapto, formyl, acyl, carboxy nitro, cyano,--PO.sub.3 (R).sub.2, R representing hydrogen, alkyl, aryl, amino or carbamoyl,the R.sub.4B radicals; ##STR2## n=0 to 2 X'=arylR.sub.4B either represents --(CH.sub.2).sub.m1 --S(O).sub.m2 --X--R.sub.10, m1=0 to 4, m2=0 to 2either m1 is different from 0, X--R.sub.10 represents amino, or whatever m1 is, X represents a single bond or --NH--, --NH--CO--, --NH--CO--NH--,R.sub.10 =alkyl, alkenyl or aryl, or hydrogen, alkyl, alkenyl, alkynyl, acyl or amino,--S--S--R.sub.4B ', R.sub.4B ' represents R.sub.4B except for amino and alkoxy, and one of R.sub.2B and R.sub.3B represents --OR.sub.4B : ##STR3## m=0 to 2, Y.sub.B ---Y.sub.1B --B--Y.sub.2B,Y.sub.1B =aryl,B=a single bond or --CO--, --O--, --NH--CO--, --CO--NH--, --O--O--(CH.sub.2).sub.p --,p=1 to 3,Y.sub.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: February 4, 1997
    Assignee: Roussel Uclaf
    Inventors: Jean C. Caille, Alain Corbier, Michel Fortin, Gilles Hamon, Simone Jouquey, Jean P. Vevert
  • Patent number: 5420138
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: May 30, 1995
    Assignee: Roussel-UCLAF
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5412101
    Abstract: The invention relates to the products: ##STR1## in which: R.sub.1 =alkyl, alkenyl, alkynyl and alkylthio,R.sub.2B, R.sub.3B are defined in the specification,m=0 to 2,Y.sub.B =--Y.sub.1B --B--Y.sub.2B,Y.sub.1B =aryl,B=a single bond or --CO--, --O--, --NH--CO--, --CO--NH--, --O--(CH.sub.2).sub.p --,p=1 to 3,Y.sub.2B represents hydrogen, cyano, carboxy, in all isomer forms and salts, their use as medicaments.
    Type: Grant
    Filed: July 24, 1992
    Date of Patent: May 2, 1995
    Assignee: Roussel-Uclaf
    Inventors: Jean C. Caille, Alain Corbier, Michel Fortin, Gilles Hamon, Simone Jouquey, Jean Vevert