Patents by Inventor Albert Kao

Albert Kao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230060770
    Abstract: A wash buffer comprising a surfactant for use in affinity and cation exchange chromatography to purify proteins of interest from protein aggregates and to remove and/or inactivate viruses. When used during affinity or cation exchange chromatography for the purification of a protein of interest, such as an antibody, the wash buffer significantly improves viral clearance from the preparation, while also reducing the levels of host cell proteins and protein aggregates. Following affinity or cation exchange chromatography with the wash buffer, the protein of interest may be further purified using other chromatography and filtration operations.
    Type: Application
    Filed: August 19, 2022
    Publication date: March 2, 2023
    Inventors: Lu WANG, Albert KAO, Zhaoqing ZHANG, Mi JIN, Tianyi ZHOU
  • Patent number: 11426706
    Abstract: A wash buffer comprising a surfactant for use in affinity and cation exchange chromatography to purify proteins of interest from protein aggregates and to remove and/or inactivate viruses. When used during affinity or cation exchange chromatography for the purification of a protein of interest, such as an antibody, the wash buffer significantly improves viral clearance from the preparation, while also reducing the levels of host cell proteins and protein aggregates. Following affinity or cation exchange chromatography with the wash buffer, the protein of interest may be further purified using other chromatography and filtration operations.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: August 30, 2022
    Assignee: Cephalon, Inc.
    Inventors: Lu Wang, Albert Kao, Zhaoqing Zhang, Mi Jin, Tianyi Zhou
  • Publication number: 20190046956
    Abstract: A wash buffer comprising a surfactant for use in affinity and cation exchange chromatography to purify proteins of interest from protein aggregates and to remove and/or inactivate viruses. When used during affinity or cation exchange chromatography for the purification of a protein of interest, such as an antibody, the wash buffer significantly improves viral clearance from the preparation, while also reducing the levels of host cell proteins and protein aggregates. Following affinity or cation exchange chromatography with the wash buffer, the protein of interest may be further purified using other chromatography and filtration operations.
    Type: Application
    Filed: June 21, 2018
    Publication date: February 14, 2019
    Inventors: Lu WANG, Albert Kao, Zhaoqing Zhang, Mi Jin, Tianyi Zhou
  • Publication number: 20160253038
    Abstract: A method and system is provided to enable precise object control for performing tasks on touch-screen devices by using only a finger. Through deriving an action-point by adding a user-definable directional offset to the touch-point, the software program can display a graphic which represents a virtual tool with its functional part located at the derived action-point and its other end extending close to or under the fingertip. Visually, the spatial relation between the virtual tool and the fingertip makes the user feel the virtual tool is directly operated by the fingertip. As the virtual tool can be programmed to move along with the user's fingertip point by point, it enables the software to perform the intended task (for example, drawing a curve) as precise as the device can detect the change in the touch location of the fingertip. Furthermore, allowing the user to customize the size and orientation of the virtual tool enables greater user control and comfort.
    Type: Application
    Filed: February 28, 2015
    Publication date: September 1, 2016
    Inventors: Albert Kao, Athena Kao, Jennifer Lee