Abstract: A therapeutically active solid unit dosage form comprising a carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and sustained release pattern upon administration, the carrier base material comprising a mixture of one or more nonionic cellulose ethers and an alkali metal carboxylate, wherein at least one of the cellulose ethers is hydroxypropylmethylcellulose having a number average molecular weight of at least 50,000.

Abstract: A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being one or more hydroxypropylmethylcelluloses or a mixture of one or more hydroxypropylmethylcelluloses and up to 30% by weight of the mixture of methylcellulose, sodium carboxymethylcellulose and/or other cellulose ether, and wherein at least one of the hydroxypropylmethylcelluloses has a methoxy content of 16-24 weight-%, a hydroxypropoxyl content of 4-32 weight-% and a number average molecular weight of at least 50,000 and wherein the carrier base material constitutes less than about one third of the weight of the solid unit dosage form.

Abstract: A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxypropylmethylcellulose has a hydroxypropoxyl content of 9-12 weight % and a number average molecular weight of less than 50,000.