Patents by Inventor Carlos R. Plata-Salaman

Carlos R. Plata-Salaman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Co-therapy for the treatment of dementia and associated behavioral manifestations comprising anticonvulsant derivatives and acetylcholinesterase inhibitors
    Publication number: 20030060423
    Abstract: The present invention describes therapy for the treatment of dementia, memory disorders and the behavioral, psychiatric and/or psychological manifestations or symptoms associated with dementia or a memory disorder comprising co-therapy with a therapeutically effective amount of one or more acetylcholinesterase inhibitors with one or more anticonvulsant derivatives.
    Type: Application
    Filed: August 28, 2002
    Publication date: March 27, 2003
    Inventor: Carlos R. Plata-Salaman
  • Alpha synuclein aggregation assays
    Publication number: 20030027210
    Abstract: The present invention provides methods to measure alpha synuclein aggregation in vitro. The methods of the present invention are useful to determine the anti-aggregation potential of compounds or to screen for drugs with anti-aggregation or dis-aggregation properties.
    Type: Application
    Filed: January 3, 2002
    Publication date: February 6, 2003
    Inventors: Daniel Benjamin, Sergey Ilyin, Carlos R. Plata-Salaman
  • CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING BIPOLAR DISORDER
    Publication number: 20020198257
    Abstract: This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: December 26, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman, Yong Moon Choi, Robert Gordon
  • Carbamate compounds for use in preventing or treating bipolar disorder
    Publication number: 20020193433
    Abstract: This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) or enantiomeric mixture wherein one enantiomer of Formula (I) predominates: 1
    Type: Application
    Filed: February 21, 2002
    Publication date: December 19, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman, Yong Moon Choi, Robert Gordon
  • CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PSYCHOTIC DISORDERS
    Publication number: 20020165272
    Abstract: This invention is directed to a method for preventing or treating psychotic disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: November 7, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman
  • Carbamate compounds for use in preventing or treating neurodegenerative disorders
    Publication number: 20020165273
    Abstract: This invention is directed to a method for preventing or treating neurodegenerative disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: November 7, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman
  • Carbamate compounds for use in the treatment of pain
    Publication number: 20020156127
    Abstract: This invention is directed to a method for the treatment of pain comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: October 24, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman
  • Carbamate compounds for use in preventing or treating movement disorders
    Publication number: 20020151585
    Abstract: This invention is directed to a method for preventing or treating movement disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: October 17, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman
  • Carbamate compounds for use in preventing or treating anxiety disorders
    Publication number: 20020143053
    Abstract: This invention is directed to a method for preventing or treating anxiety disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): 1
    Type: Application
    Filed: February 21, 2002
    Publication date: October 3, 2002
    Inventors: Carlos R. Plata-Salaman, Boyu Zhao, Roy E. Twyman
  • Method of treating neurodegenerative disorders via inhibition of amyloid beta peptide binding
    Patent number: 6441049
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: August 27, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Allen B. Reitz, David A. Demeter, Daniel H. S. Lee, Hoau-Yan Wang, Robert H. Chen, Tina Morgan Ross, Malcolm K. Scott, Carlos R. Plata-Salaman
  • Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
    Publication number: 20020107283
    Abstract: This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: 1
    Type: Application
    Filed: July 16, 2001
    Publication date: August 8, 2002
    Inventors: Ellen E. Codd, Richard P. Shank, Katherine E. Rogers, Carlos R. Plata-Salaman, Boyu Zhao
  • Anticonvulsant derivatives useful for the treatment of depression
    Publication number: 20020094960
    Abstract: Anticonvulsant derivatives useful for treating depression as monotherapy or combination therapy are disclosed.
    Type: Application
    Filed: July 27, 2001
    Publication date: July 18, 2002
    Inventors: Carlos R. Plata-Salaman, Josue Bacaltchuk, Pedro A.S. Prado-Lima
  • METHOD OF TREATING NEURODEGENERATIVE DISORDERS VIA INHIBITION OF AMYLOID BETA PEPTIDE BINDING
    Publication number: 20020013374
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: May 27, 1999
    Publication date: January 31, 2002
    Inventors: ALLEN B. REITZ, DAVID A. DEMETER, DANIEL H.S. LEE, HOAU-YAN WANG, ROBERT H. CHEN, TINA MORGAN ROSS, MALCOLM K. SCOTT, CARLOS R. PLATA-SALAMAN
  • Method for diagnosis of Alzheimer's disease
    Publication number: 20020006627
    Abstract: The present invention is directed to a method of diagnosing Alzheimer's disease involving analysis of a test sample in such a way that &bgr;-amyloid1-42 or A&bgr;3pE is completely or nearly completely (i.e., thoroughly) dissociated from binding proteins prior to the analysis of the levels of &bgr;-amyloid1-42 or A&bgr;3pE.
    Type: Application
    Filed: January 31, 2001
    Publication date: January 17, 2002
    Inventors: Allen B. Reitz, Adrian Dawkes, Carlos R. Plata Salaman, Haou-Yan Wang