Patents by Inventor Claudia K. Derian

Claudia K. Derian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine-containing macroheterococylic compounds as kinase inhibitors
    Patent number: 7759331
    Abstract: This invention is directed to pyridine-containing macroheterocyclic compounds useful as kinase inhibitors, methods for producing such compounds and methods for treating or preventing a kinase mediated disorder.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: July 20, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Han-Cheng Zhang, Llorente Vincente R. Bonaga, Claudia K. Derian, Bruce E. Maryanoff, Hong Ye
  • Guinea pig proteinase-activated receptor 4 and its activating peptide
    Publication number: 20080248495
    Abstract: This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thrombosis.
    Type: Application
    Filed: November 14, 2006
    Publication date: October 9, 2008
    Inventors: Andrew L. Darrow, Claudia K. Derian, Michael F. Addo, Patricia Andrade-Gordon
  • Pyridine-containing macroheterococylic compounds as kinase inhibitors
    Publication number: 20070213352
    Abstract: This invention is directed to pyridine-containing macroheterocyclic compounds useful as kinase inhibitors, methods for producing such compounds and methods for treating or preventing a kinase mediated disorder.
    Type: Application
    Filed: March 9, 2007
    Publication date: September 13, 2007
    Inventors: Han-Cheng Zhang, Llorente Vicente R. Bonaga, Claudia K. Derian, Bruce E. Maryanoff, Hong Ye
  • Guinea pig proteinase-activated receptor 4 and its activating peptide
    Patent number: 7179887
    Abstract: This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thrombosis.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: February 20, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Andrew L. Darrow, Claudia K. Derian, Michael F. Addo, Patricia Andrade-Gordon
  • Labeled chemotactic peptides to image focal sites of infection or inflammation
    Patent number: 5792444
    Abstract: The invention relates to a method of detecting a site of infection or inflammation, and a method for treating such infection or inflammation, in an individual by administering to the individual a diagnostically or therapeutically effective amount of detectably labeled, therapeutic, or therapeutically-conjugated, chemotactic peptide that accumulates substantially at the infected or inflamed site, said chemotactic peptide having the general structureX--Y--Leu--Phe--?Z!.sub.n --Wwherein:X is an amino protecting group,Y is an amino acid residue,Z is a spacer sequence,n is 0 or 1, andW is a labeling or attachment substituent.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: August 11, 1998
    Assignees: The General Hospital Corporation, Johnson Matthey, Inc., Ortho Pharmaceutical Corporation
    Inventors: Alan J. Fischman, Howard F. Solomon, Claudia K. Derian, Gary J. Bridger, John D. Higgins, III, Scott K. Larsen, Pedro E. Hernandez, Robert H. Rubin, H. William Strauss, Anthony J. Fuccello, Daniel J. Kroon
  • Anticonvulsant derivatives useful in treating psoriasis
    Patent number: 5760006
    Abstract: The use of compounds of the following formula I: ##STR1## for treating psoriasis is disclosed.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: June 2, 1998
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Richard P. Shank, Claudia K. Derian