Patents by Inventor Claus Braestrup

Claus Braestrup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-(butenyl substituted) azaheterocyclic carboxylic acids
    Patent number: 5010090
    Abstract: 1-Aminobut-3-en derivatives having optionally substituted furanyl, thienyl, pyridyl and/or pyrrolyl in the 4-position and 3-carboxypiperidin-1-yl, 3-carboxytetrahydropyrid-1-yl or 3 carboxymethylpyrrolidin-1-yl in the 1-position potentiate GABA-ergic neurotransmission.
    Type: Grant
    Filed: October 7, 1988
    Date of Patent: April 23, 1991
    Assignee: Novo Nordisk A/S.
    Inventors: Frederik C. Gronvald, Claus Braestrup
  • 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof
    Patent number: 4751222
    Abstract: Novel 2,3,4,5-tetrahydro-1H-3-benzazepines which in the 5-position have furyl, thienyl, pyridyl, or ring systems consisting of phenyl ortho condensed with a benzen, cyclohexan, cyclohexen, cyclopentan or cyclopenten ring wherein one of the carbon atoms may be exchanged with oxygen, sulphur or nitrogen, have interesting central nervous system and cardiovascular effects.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: June 14, 1988
    Assignee: Novo Industri A/S
    Inventors: Claus Braestrup, Peter H. Andersen, Poul Borrevang, Frederik C. Gr nvald, Louis B. Hansen, Rolf Hohlweg
  • Process for determining the concentration of benzodiazepines in a body fluid
    Patent number: 4280993
    Abstract: A process for determining the concentration of benzodiazepines in a body liquid comprising the steps of contacting freeze-dried brain tissue with tritium labelled flunitrazepam to bond labelled flunitrazepam to receptor sites of the brain tissue, determining the concentration of labelled flunitrazepam of the brain tissue, incubating the brain tissue containing labelled flunitrazepam with a sample of body liquid containing benzodiazepine, the concentration of which is to be determined, to induce displacement of labelled flunitrazepam from said brain tissue, determining the concentration of labelled flunitrazepam bonded to the brain tissue after establishing equilibrium conditions and determining the concentration of benzodiazepine in the body liquid based on the change of concentration of labelled flunitrazepam induced by benzodiazepine contained in the sample.
    Type: Grant
    Filed: January 18, 1979
    Date of Patent: July 28, 1981
    Inventors: Claus Braestrup, Richard F. Squires