Patents by Inventor Daniel Mufson

Daniel Mufson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11065400
    Abstract: Inhalation delivery of aerosols containing small particles is described. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present disclosure, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: July 20, 2021
    Assignee: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Publication number: 20170281884
    Abstract: The present disclosure relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present disclosure, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Application
    Filed: June 26, 2017
    Publication date: October 5, 2017
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Patent number: 9687487
    Abstract: Inhalation delivery of aerosols containing small particles from a device that forms drug containing aerosols for use in inhalation therapy. A device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: June 27, 2017
    Assignee: Alexza Pharmaceuticals, Inc.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Patent number: 9636254
    Abstract: Methods, system and apparatus for relieving pressure in an organ such as, but not limited to, the eye are disclosed. The method includes implanting a bioabsorbable channel into the selected area of the organ using a delivery apparatus.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 2, 2017
    Assignee: AqueSys, Inc.
    Inventors: Dao-Yi Yu, Cory Anderson, Roelof Trip, Ying Yang, Hoang Van Nguyen, Surag Mantri, Er-Ning Su, Stephen Cringle, James McCrea, Daniel Mufson, Colin Tan
  • Patent number: 9439907
    Abstract: The present application relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition of a drug to form a vapor, wherein the coated composition is in the form of a film less than 10? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method involves: (a) heating a substrate coated with a composition of a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: September 13, 2016
    Assignee: ALEXZA PHARMACEUTICAL, INC.
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Patent number: 9308208
    Abstract: A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 12, 2016
    Assignee: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Martin J. Wensley, Daniel Mufson, Craig C. Hodges, Peter M. Lloyd, Daniel D. Rogers
  • Publication number: 20150157635
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided.
    Type: Application
    Filed: February 17, 2015
    Publication date: June 11, 2015
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Patent number: 8955512
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: February 17, 2015
    Assignee: Alexza Pharmaceuticals, Inc.
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Publication number: 20140060532
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present invention, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Application
    Filed: November 13, 2013
    Publication date: March 6, 2014
    Applicant: Alexza Pharmaceuticals, Inc.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Publication number: 20140066618
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 ?thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 6, 2014
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Publication number: 20130276779
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.
    Type: Application
    Filed: March 27, 2013
    Publication date: October 24, 2013
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Publication number: 20120197175
    Abstract: The invention generally relates to shunts in which at least a portion of the body includes a drug.
    Type: Application
    Filed: December 8, 2011
    Publication date: August 2, 2012
    Applicant: AQUESYS, INC.
    Inventors: Christopher Horvath, Ronald D. Bache, Laszlo O. Romoda, Dao-Yi Yu, Cory Anderson, Roelof Trip, Ying Yang, Hoang Van Nguyen, Surag Mantri, Er-Ning Su, Stephen Cringle, James McCrea, Daniel Mufson, Colin Tan, Richard L. Lindstrom
  • Patent number: 8074644
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: December 13, 2011
    Assignee: Alexza Pharmaceuticals, Inc.
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Publication number: 20110240022
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present invention, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Application
    Filed: April 1, 2011
    Publication date: October 6, 2011
    Applicant: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Publication number: 20110240013
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming a vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
    Type: Application
    Filed: April 1, 2011
    Publication date: October 6, 2011
    Applicant: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Ron L. Hale, Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Soonho Song, Martin J. Wensley, Daniel J. Myers, Jeffrey A. McKinney, Reynaldo J. Quintana, Joshua D. Rabinowitz
  • Publication number: 20110118745
    Abstract: Methods, systems and apparatus for relieving pressure in an organ such as, but not limited to, the eye are disclosed. The method includes implanting a bioabsorbable, channel into the selected area of the organ using a delivery apparatus.
    Type: Application
    Filed: December 9, 2010
    Publication date: May 19, 2011
    Applicant: AQUESYS, INC.
    Inventors: DAO-YI YU, Cory Anderson, Roelof Trip, Ying Yang, Hoang Van Nguyen, Surag Mantri, Er-Ning Su, Stephen Cringle, James McCrea, Daniel Mufson, Colin Tan
  • Patent number: 7942147
    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present invention, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: May 17, 2011
    Assignee: Alexza Pharmaceuticals, Inc.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Publication number: 20100294268
    Abstract: A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.
    Type: Application
    Filed: July 30, 2010
    Publication date: November 25, 2010
    Applicant: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Martin J. WENSLEY, Daniel MUFSON, Craig C. HODGES, Peter M. LLOYD, Daniel D. ROGERS
  • Patent number: 7766013
    Abstract: A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: August 3, 2010
    Assignee: Alexza Pharmaceuticals, Inc.
    Inventors: Martin J. Wensley, Daniel Mufson, Craig C. Hodges, Peter M. Lloyd, Daniel D. Rogers
  • Publication number: 20100121248
    Abstract: Methods, system and apparatus for relieving pressure in an organ such as, but not limited to, the eye are disclosed. The method includes implanting a bioabsorbable channel into the selected area of the organ using a delivery apparatus.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 13, 2010
    Applicant: AqueSys, Inc.
    Inventors: Dao-Yi Yu, Cory Anderson, Roelof Trip, Ying Yang, Hoang Van Nguyen, Surag Mantri, Er-Ning Su, Stephen Cringle, James McCrea, Daniel Mufson, Colin Tan