Abstract: The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 &mgr;m, preferably less than about 20 &mgr;m, and preferably about 0.1 &mgr;m to about 10 &mgr;m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.

Abstract: The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 &mgr;m, preferably less than about 20 &mgr;m, and preferably about 0.1 &mgr;m to about 10 &mgr;m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.

Abstract: The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 &mgr;m, preferably less than about 20 &mgr;m, and preferably about 0.1 &mgr;m to about 10 &mgr;m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.

Abstract: A compound ball simulates the performance of a regulation size baseball, softball, and golf ball. It is formed of spherical outer and inner shells dimensioned to abut one another or to provide a spacing between them. The outer shell is formed of molded polymeric material with circular apertures spaced over its surface. The inner shell is gas filled and resiliently rebounds in response to being compressed by the outer shell upon deformation of the outer shell in response to being hit, as by a bat or club. The apertures in the outer shell permit air to pass trough the apertures when the compound ball is in flight. The inner shell provides mass and impact rebound within the outer shell for simulating the action of a regulation ball when thrown, caught, hit or impacts an object. The outer shell may also contain raised dimpling to impart greater aerodynamic drag on the compound ball, further limiting its flight and range, or altering its performance.

Abstract: A composition, comprising an agent, a carrier admixed with the agent to form a mixture, and a film-forming polymer coating around the mixture which is insoluble in a selected solvent. A biocidal composition, comprising a biocide, such as an aldehyde, a carrier admixed with the aldehyde to form a mixture, and a film-forming polymer coating around the mixture which is insoluble in a selected solvent. The composition of the invention further comprising an acidifying agent admixed with the aldehyde. The composition of the invention and an activator. An article of manufacture, comprising the composition of the invention contained inside a fluid-permeable mesh bag. A method of making a biocidal composition, comprising admixing a carrier with an aldehyde to form a mixture, and coating the mixture with a film-forming polymer coating which is insoluble in a selected solvent.

Abstract: The present invention relates to polymeric microspheres as injectable, drug-delivery systems for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient.