Patents by Inventor Deborah J. Johnson

Deborah J. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and dosage forms for controlled delivery of oxycodone
    Publication number: 20040010000
    Abstract: Dosage forms and methods for the controlled release of oxycodone over a prolonged period of time are described. The sustained release dosage forms provide therapeutically effective average steady-state plasma oxycodone concentrations when administered once per day. This once-a-day dosing regimen results in only one peak plasma oxycodone concentration occurrence in each 24 hour period that occurs at a later time after administration and exhibits a lesser magnitude than the peak plasma oxycodone concentration that occurs following administration of oxycodone in an immediate-release dosage form and other prior art extended release dosage forms.
    Type: Application
    Filed: April 25, 2003
    Publication date: January 15, 2004
    Inventors: Atul D. Ayer, Padmaja Shivanand, Nishit B. Modi, Sonya Seroff, Michael A. DesJardin, Tracy A. Fink, Linda M. Hearney, Deborah J. Johnson, Clark P. Allphin
  • Dosage forms and compositions for osmotic delivery of variable dosages of oxycodone
    Publication number: 20030224051
    Abstract: Dosage forms, compositions and methods for the controlled release of oxycodone over a prolonged period of time are described. The present invention discloses a novel means for delivering varying doses of oxycodone using a drug composition having only oxycodone, a polymer carrier and varying amounts of salt to provide a particular viscosity of the hydrated drug core for delivery of the drug at the desired release rate. The present invention functions by modulating the viscosity of the hydrated drug layer in operation by the addition or reduction of salts in the drug composition. The system is independent of solubility enhancers or pH modifiers. The sustained release dosage forms provide therapeutically effective average steady-state plasma oxycodone concentrations when administered once per day.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 4, 2003
    Inventors: Tracy A. Fink, Atul D. Ayer, Deborah J. Johnson, Padmaja Shivanand, Clark P. Allphin
  • Analgesic tablet compositions
    Patent number: 6284274
    Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: September 4, 2001
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson
  • Controlled release tablet compositions
    Patent number: 6077538
    Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: June 20, 2000
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson
  • Compositions containing opiate analgesics
    Patent number: 5948787
    Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: September 7, 1999
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson