Patents by Inventor Douglas John Jenkins

Douglas John Jenkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED N-HETEROCYCLE DERIVATIVES AND METHODS OF THEIR USE
    Publication number: 20090227585
    Abstract: The present invention is directed to substituted N-heterocycle derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.
    Type: Application
    Filed: May 18, 2009
    Publication date: September 10, 2009
    Applicant: Wyeth
    Inventors: Paige Erin Mahaney, Lori Krim Gavrin, Douglas John Jenkins
  • SUBSTITUTED BENZO[d][1,3]OXAZIN-2(4H)-ONES AND RELATED DERIVATIVES AND THEIR USES FOR MODULATING THE PROGESTERONE RECEPTOR
    Publication number: 20090197878
    Abstract: Compounds of formula (I), or pharmaceutically acceptable salts thereof, are provided, wherein R1-R6 and X are defined herein. Also provided are methods of preparing the compounds of formula (I), pharmaceutical compositions and kits containing a compound of formula (I), as are methods of treating endometriosis, hormone-dependent carcinomas, leiomyoma, fibroids, dysfunctional bleeding, polycystic ovary syndrome, and menopause related symptoms; methods of contraception; methods of providing hormone replacement therapy; methods of stimulating food intake; methods of synchronizing estrus; and methods of treating symptoms of premenstrual syndrome and premenstrual dysphoric disorder by administering to a mammal in need thereof a pharmaceutically effective amount of a compound of formula (I).
    Type: Application
    Filed: January 29, 2009
    Publication date: August 6, 2009
    Applicant: Wyeth
    Inventors: Thomas Joseph Commons, Douglas John Jenkins, Eugene John Trybulski, Andrew Fensome
  • Substituted N-heterocycle derivatives and methods of their use
    Patent number: 7550485
    Abstract: The present invention is directed to substituted N-heterocycle derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.
    Type: Grant
    Filed: October 12, 2004
    Date of Patent: June 23, 2009
    Assignee: Wyeth
    Inventors: Paige Erin Mahaney, Lori Krim Gavrin, Douglas John Jenkins
  • SUBSTITUTED ARYL OXIMES
    Publication number: 20080293790
    Abstract: The present invention relates to substituted aryl oximes and methods of using them.
    Type: Application
    Filed: July 28, 2008
    Publication date: November 27, 2008
    Applicant: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • Substituted aryloximes
    Patent number: 7420083
    Abstract: The present invention relates to substituted aryl oximes and methods of using them.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: September 2, 2008
    Assignee: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE
    Publication number: 20080161366
    Abstract: The present invention is directed to aminoalkyl-substituted aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
    Type: Application
    Filed: December 12, 2007
    Publication date: July 3, 2008
    Applicant: Wyeth
    Inventors: Casey Cameron McComas, Stephen Todd Cohn, Matthew Lantz Crawley, Andrew Fensome, Joel Adam Goldberg, Douglas John Jenkins, Callain Younghee Kim, Paige Erin Mahaney, Charles William Mann, Michael Anthony Marella, David John O'Neill, Joseph Peter Sabatucci, Eugene Anthony Terefenko, Eugene John Trybulski, An Thien Vu, Richard Page Woodworth, Puwen Zhang
  • Substituted indole oximes
    Patent number: 7342039
    Abstract: The present invention relates to substituted indole oximes and methods of using them.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: March 11, 2008
    Assignee: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • Pyrrolo-naphthyl acids and methods for using them
    Patent number: 7186749
    Abstract: The present invention relates to pyrrolo-naphthyl compounds of the formula and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: March 6, 2007
    Assignee: Wyeth
    Inventors: Thomas J. Commons, Douglas John Jenkins
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Publication number: 20040157887
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 12, 2004
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Patent number: 6706737
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: March 16, 2004
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins
  • Dry-blend pharmaceutical formulations
    Patent number: 6667323
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: December 23, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda D. Whittall
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Patent number: 6667321
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: December 23, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • Dry blend pharmaceutical formulations
    Patent number: 6667324
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: December 23, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Publication number: 20030225136
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Application
    Filed: May 8, 2003
    Publication date: December 4, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • DRY BLEND PHARMACEUTICAL FORMULATIONS
    Publication number: 20030225137
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Application
    Filed: May 16, 2003
    Publication date: December 4, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • DRY-BLEND PHARMACEUTICAL FORMULATIONS
    Publication number: 20030225135
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Application
    Filed: May 7, 2003
    Publication date: December 4, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda D. Whittall
  • Granulated pharmaceutical formulations and methods for making the same
    Patent number: 6653329
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: November 25, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Publication number: 20030096845
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Application
    Filed: July 3, 2002
    Publication date: May 22, 2003
    Inventors: Robert R. Whittle, Frederick D. Sancillio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall
  • 4-substituted-3-substituted-amino-cyclobut-3-ene-1,2-diones and analogs thereof as novel potassium channel openers
    Publication number: 20020177613
    Abstract: 4-Substituted-3-substituted-amino-cyclobut-3-ene-1,2-diones having the Formula (I): 1
    Type: Application
    Filed: March 12, 2002
    Publication date: November 28, 2002
    Applicant: American Home Products Corporation
    Inventors: John Anthony Butera, Joseph Richard Lennox, Douglas John Jenkins
  • Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
    Patent number: 6444689
    Abstract: Compounds represented by formula (Ia) are disclosed by the invention, along with compositions and complexes thereof, optionally in combination with compounds of formula (Ib). Pharmaceutical formulations and methods of making and using such compounds are also disclosed.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: September 3, 2002
    Inventors: Robert R. Whittle, Frederick D. Sancilio, Grayson Walker Stowell, Douglas John Jenkins, Linda B. Whittall