Patents by Inventor Flentke George R.

Flentke George R. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of dipeptidyl-aminopeptidase type IV
    Patent number: 5462928
    Abstract: The invention features an inhibitor of DP-IV, having the structure: ##STR1## wherein m is an integer between 0 and 10, inclusive; A and A' are L-amino acid residues such that the A in each repeating bracketed unit can be a different amino acid residue; the C bonded to B is in the L-configuration; the bonds between A and N, A' and C, and between A' and N are peptide bonds; and each X.sup.1 and X.sup.2 is, independently, a hydroxyl group or a group capable of being hydrolyzed to a hydroxyl group at physiological pH.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: October 31, 1995
    Assignees: New England Medical Center Hospitals, Inc., Tufts University
    Inventors: William W. Bachovchin, Andrew G. Plaut, Flentke George R.