Patents by Inventor Francisco Jao

Francisco Jao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080021102
    Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
    Type: Application
    Filed: July 25, 2007
    Publication date: January 24, 2008
    Applicant: Alza Corporation
    Inventors: George Guittard, Francisco Jao, Susan Marks, David Kidney, Fernando Gumucio, Suneel Gupta, Gayatri Sathyan
  • Publication number: 20070184112
    Abstract: A dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment occupied by the osmotic core. The osmotic core includes an active agent composition and a light push layer. A passageway is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation. The bi-layer membrane system and the osmotic core are formulated and formed to provide controlled release of the active agent included in the active agent composition, while simultaneously facilitating increased loading of active agent within a dosage form of given dimension and increasing the delivery efficiency of such active agent relative to prior osmotic dosage forms including a push layer.
    Type: Application
    Filed: March 12, 2007
    Publication date: August 9, 2007
    Applicant: ALZA CORPORATION
    Inventors: Patrick Wong, Francisco Jao, David Edgren, Robert Skluzacek, Shu Li
  • Patent number: 6919092
    Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: July 19, 2005
    Assignee: ALZA Corporation
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Publication number: 20050019409
    Abstract: The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use. The active agent dosage form is a multilayer core, often bilayer, formed of polymer matrices that swell upon contact with the fluids of the stomach. At least one layer of the multilayered dosage form includes an active agent. A portion of the polymer matrices are surrounded by a band of insoluble material that prevents the covered portion of the polymer matrices from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
    Type: Application
    Filed: August 9, 2004
    Publication date: January 27, 2005
    Inventors: David Edgren, Francisco Jao, Patrick Wong
  • Patent number: 6797283
    Abstract: The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use. The active agent dosage form is a multilayer core, often bilayer, formed of polymer matrices that swell upon contact with the fluids of the stomach. At least one layer of the multilayered dosage form includes an active agent. A portion of the polymer matrices are surrounded by a band of insoluble material that prevents the covered portion of the polymer matrices from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: September 28, 2004
    Assignee: Alza Corporation
    Inventors: David E. Edgren, Francisco Jao, Patrick S. -L. Wong
  • Publication number: 20040067300
    Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 8, 2004
    Inventors: David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
  • Publication number: 20040043943
    Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
    Type: Application
    Filed: August 20, 2003
    Publication date: March 4, 2004
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Publication number: 20030185888
    Abstract: The present invention includes a dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile. In each embodiment, the dosage form of the present invention includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment that is occupied by the osmotic core. The osmotic core of the dosage form of the present invention includes and active agent composition and a light push layer. The dosage form of the present invention additionally includes a passageway that is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation.
    Type: Application
    Filed: March 31, 2003
    Publication date: October 2, 2003
    Inventors: Patrick S.L. Wong, Francisco Jao, David E. Edgren, Robert R. Skluzacek, Shu S.L. Li
  • Patent number: 6548083
    Abstract: The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: April 15, 2003
    Assignee: Alza Corporation
    Inventors: Patrick S.-L. Wong, Liang-Chang Dong, David E. Edgren, Felix Theeuwes, Phyllis I. Gardner, Francisco Jao, Jason J. Wan
  • Publication number: 20020155155
    Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.
    Type: Application
    Filed: February 15, 2002
    Publication date: October 24, 2002
    Inventors: David E. Edgren, Patrick S. L. Wong, Francisco Jao, Yolanda M. Puga
  • Patent number: 6365183
    Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: April 2, 2002
    Assignee: ALZA Corporation
    Inventors: David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
  • Patent number: 6262115
    Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: July 17, 2001
    Assignee: ALZA Coporation
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Publication number: 20010005728
    Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
    Type: Application
    Filed: February 16, 2001
    Publication date: June 28, 2001
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Patent number: 6124355
    Abstract: A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: September 26, 2000
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Patent number: 6120803
    Abstract: The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
    Type: Grant
    Filed: August 10, 1998
    Date of Patent: September 19, 2000
    Assignee: ALZA Corporation
    Inventors: Patrick S. L. Wong, Liang-Chang Dong, David E. Edgren, Felix Theeuwes, Phyllis I. Gardner, Francisco Jao, Jason J. Wan
  • Patent number: 5912268
    Abstract: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
    Type: Grant
    Filed: February 26, 1997
    Date of Patent: June 15, 1999
    Assignee: Alza Corporation
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
  • Patent number: 5840754
    Abstract: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: November 24, 1998
    Assignee: ALZA Corporation
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando Gumucio
  • Patent number: 5674895
    Abstract: A composition comprising oxybutynin and a device comprising oxybutynin are disclosed for oxybutynin therapy.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: October 7, 1997
    Assignee: Alza Corporation
    Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando Gumucio
  • Patent number: 5310561
    Abstract: A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.
    Type: Grant
    Filed: September 21, 1992
    Date of Patent: May 10, 1994
    Assignee: Alza Corporation
    Inventors: Francisco Jao, Hoa T. Huynh, Patrick S. L. Wong
  • Patent number: 5246709
    Abstract: A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.
    Type: Grant
    Filed: September 21, 1992
    Date of Patent: September 21, 1993
    Assignee: Alza Corporation
    Inventors: Francisco Jao, Hoa T. Huynh, Patrick S. L. Wong