Patents by Inventor Francisco Jao
Francisco Jao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080021102Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.Type: ApplicationFiled: July 25, 2007Publication date: January 24, 2008Applicant: Alza CorporationInventors: George Guittard, Francisco Jao, Susan Marks, David Kidney, Fernando Gumucio, Suneel Gupta, Gayatri Sathyan
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Publication number: 20070184112Abstract: A dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment occupied by the osmotic core. The osmotic core includes an active agent composition and a light push layer. A passageway is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation. The bi-layer membrane system and the osmotic core are formulated and formed to provide controlled release of the active agent included in the active agent composition, while simultaneously facilitating increased loading of active agent within a dosage form of given dimension and increasing the delivery efficiency of such active agent relative to prior osmotic dosage forms including a push layer.Type: ApplicationFiled: March 12, 2007Publication date: August 9, 2007Applicant: ALZA CORPORATIONInventors: Patrick Wong, Francisco Jao, David Edgren, Robert Skluzacek, Shu Li
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Patent number: 6919092Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.Type: GrantFiled: February 16, 2001Date of Patent: July 19, 2005Assignee: ALZA CorporationInventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Publication number: 20050019409Abstract: The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use. The active agent dosage form is a multilayer core, often bilayer, formed of polymer matrices that swell upon contact with the fluids of the stomach. At least one layer of the multilayered dosage form includes an active agent. A portion of the polymer matrices are surrounded by a band of insoluble material that prevents the covered portion of the polymer matrices from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.Type: ApplicationFiled: August 9, 2004Publication date: January 27, 2005Inventors: David Edgren, Francisco Jao, Patrick Wong
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Patent number: 6797283Abstract: The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use. The active agent dosage form is a multilayer core, often bilayer, formed of polymer matrices that swell upon contact with the fluids of the stomach. At least one layer of the multilayered dosage form includes an active agent. A portion of the polymer matrices are surrounded by a band of insoluble material that prevents the covered portion of the polymer matrices from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.Type: GrantFiled: December 22, 1999Date of Patent: September 28, 2004Assignee: Alza CorporationInventors: David E. Edgren, Francisco Jao, Patrick S. -L. Wong
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Publication number: 20040067300Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.Type: ApplicationFiled: September 26, 2003Publication date: April 8, 2004Inventors: David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
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Publication number: 20040043943Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.Type: ApplicationFiled: August 20, 2003Publication date: March 4, 2004Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Publication number: 20030185888Abstract: The present invention includes a dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile. In each embodiment, the dosage form of the present invention includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment that is occupied by the osmotic core. The osmotic core of the dosage form of the present invention includes and active agent composition and a light push layer. The dosage form of the present invention additionally includes a passageway that is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation.Type: ApplicationFiled: March 31, 2003Publication date: October 2, 2003Inventors: Patrick S.L. Wong, Francisco Jao, David E. Edgren, Robert R. Skluzacek, Shu S.L. Li
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Patent number: 6548083Abstract: The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.Type: GrantFiled: July 13, 2000Date of Patent: April 15, 2003Assignee: Alza CorporationInventors: Patrick S.-L. Wong, Liang-Chang Dong, David E. Edgren, Felix Theeuwes, Phyllis I. Gardner, Francisco Jao, Jason J. Wan
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Publication number: 20020155155Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.Type: ApplicationFiled: February 15, 2002Publication date: October 24, 2002Inventors: David E. Edgren, Patrick S. L. Wong, Francisco Jao, Yolanda M. Puga
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Patent number: 6365183Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.Type: GrantFiled: March 23, 1999Date of Patent: April 2, 2002Assignee: ALZA CorporationInventors: David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
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Patent number: 6262115Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.Type: GrantFiled: March 29, 1999Date of Patent: July 17, 2001Assignee: ALZA CoporationInventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Publication number: 20010005728Abstract: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.Type: ApplicationFiled: February 16, 2001Publication date: June 28, 2001Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Patent number: 6124355Abstract: A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.Type: GrantFiled: May 13, 1998Date of Patent: September 26, 2000Inventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Patent number: 6120803Abstract: The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.Type: GrantFiled: August 10, 1998Date of Patent: September 19, 2000Assignee: ALZA CorporationInventors: Patrick S. L. Wong, Liang-Chang Dong, David E. Edgren, Felix Theeuwes, Phyllis I. Gardner, Francisco Jao, Jason J. Wan
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Patent number: 5912268Abstract: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.Type: GrantFiled: February 26, 1997Date of Patent: June 15, 1999Assignee: Alza CorporationInventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando E. Gumucio
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Patent number: 5840754Abstract: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.Type: GrantFiled: September 5, 1996Date of Patent: November 24, 1998Assignee: ALZA CorporationInventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando Gumucio
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Patent number: 5674895Abstract: A composition comprising oxybutynin and a device comprising oxybutynin are disclosed for oxybutynin therapy.Type: GrantFiled: May 22, 1995Date of Patent: October 7, 1997Assignee: Alza CorporationInventors: George V. Guittard, Francisco Jao, Susan M. Marks, David J. Kidney, Fernando Gumucio
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Patent number: 5310561Abstract: A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.Type: GrantFiled: September 21, 1992Date of Patent: May 10, 1994Assignee: Alza CorporationInventors: Francisco Jao, Hoa T. Huynh, Patrick S. L. Wong
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Patent number: 5246709Abstract: A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.Type: GrantFiled: September 21, 1992Date of Patent: September 21, 1993Assignee: Alza CorporationInventors: Francisco Jao, Hoa T. Huynh, Patrick S. L. Wong