Patents by Inventor Howard J. Lambert

Howard J. Lambert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and compounds for treating inflammatory bowel disease
    Patent number: 4312806
    Abstract: The present invention relates to novel compounds and a method for the prophylaxis and treatment of Inflammatory Bowel Disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage form of an azobenzene compound of formula I or a pharmacologically acceptable salt, which is reductively cleaved to 5-aminosalicylic acid (5-ASA) by bacteria in the large intestine.
    Type: Grant
    Filed: March 2, 1981
    Date of Patent: January 26, 1982
    Assignee: G. D. Searle & Co.
    Inventors: Howard J. Lambert, Barnett S. Pitzele
  • Microsealed pharmaceutical delivery device
    Patent number: 4053580
    Abstract: The present invention is concerned with a pharmaceutical delivery device comprising a biologically acceptable silicone polymer matrix having microsealed compartments of 10-200 microns throughout, wherein the microsealed compartments contain a pharmaceutical in a hydrophilic solvent system. The biologically acceptable silicone polymer matrix is formed by in situ cross linking of a liquid, biologically acceptable silicone polymer in an emulsion of pharmaceutical in the hydrophilic solvent system and liquid biologically acceptable silicone polymer. The biologically acceptable silicone polymer matrix is placed in a sealed or unsealed biologically acceptable polymer container.
    Type: Grant
    Filed: September 20, 1976
    Date of Patent: October 11, 1977
    Assignee: G. D. Searle & Co.
    Inventors: Yie W. Chien, Howard J. Lambert
  • Method for making a microsealed delivery device
    Patent number: 3992518
    Abstract: The present invention is concerned with a pharmaceutical delivery device comprising a biologically acceptable silicone polymer matrix having microsealed compartments of 10-200 microns throughout, wherein the microsealed compartments contain a pharmaceutical in a hydrophilic solvent system. The biologically acceptable silicone polymer matrix is formed by in situ cross linking of a liquid, biologically acceptable silicone polymer in an emulsion of pharmaceutical in the hydrophilic solvent system and liquid biologically acceptable silicone polymer. The biologically acceptable silicone polymer matrix is placed in a sealed or unsealed biologically acceptable polymer container.
    Type: Grant
    Filed: September 29, 1975
    Date of Patent: November 16, 1976
    Assignee: G. D. Searle & Co.
    Inventors: Yie W. Chien, Howard J. Lambert
  • Microsealed pharmaceutical delivery device
    Patent number: 3946106
    Abstract: The present invention is concerned with a pharmaceutical delivery device comprising a biologically acceptable silicone polymer matrix having microsealed compartments of 10-200 microns throughout, wherein the microsealed compartments contain a pharmaceutical in a hydrophilic solvent system. The biologically acceptable silicone polymer matrix is formed by in situ cross linking of a liquid, biologically acceptable silicone polymer in an emulsion of pharmaceutical in the hydrophilic solvent system and liquid biologically acceptable silicone polymer. The biologically acceptable silicone polymer matrix is placed in a sealed or unsealed biologically acceptable polymer container.
    Type: Grant
    Filed: October 24, 1974
    Date of Patent: March 23, 1976
    Assignee: G. D. Searle & Co.
    Inventors: Yie W. Chien, Howard J. Lambert