Abstract: Various exemplary drug delivery devices with a multi-dispensing head, drug products utilizing the same, and methods of using drug delivery devices with a multi-dispensing head are provided. In general, a nasal drug delivery device is configured to dispense a drug therefrom into a nose. In an exemplary embodiment, the drug delivery device includes two tips each configured to be positioned in or adjacent to a nostril. The two tips are configured to be positioned in or adjacent to the nostrils simultaneously.

Abstract: A grip accessory for a manual injection device comprises a housing having a generally hollow body for supporting a manual injection device therein. The housing comprises a distal portion comprising a first opening into which a manual injection device can be inserted, a proximal portion comprising a second opening through which a needle of the manual injection device is extendable, the proximal portion comprising a skin contacting surface at a proximal end of the device. An intermediate portion extends between the proximal and distal portions and guide means is provided on an interior surface of the distal portion for guiding a plunger rod of an injection device during delivery of an injection.

Abstract: A grip accessory for a manual injection device comprises a housing comprising a generally hollow body configured to support a manual injection device therein. The housing comprises a distal portion comprising a first opening into which a manual injection device can be inserted, a proximal portion having a second opening through which the needle of the manual injection device extends. The proximal portion comprises a skin contacting surface at a proximal end of the device that can be placed against an injection site. An intermediate portion extends between the proximal and distal portions.

Abstract: Various exemplary drug delivery devices with a mechanical stop, drug products utilizing the same, and methods of using drug delivery devices with a mechanical stop are provided. In general, a nasal drug delivery device is configured to dispense therefrom first and second doses of a drug therefrom into a nose. The drug delivery device includes a mechanical stop configured to provide a pause between the delivery of the first and second doses. During the pause, a user of the drug delivery device can move the drug delivery device from one nostril, into which the first dose was sprayed, to another nostril, into which the second dose can be sprayed. The mechanical stop is configured to hold the drug delivery device in a static delivery state.

Abstract: Various exemplary drug syringes with a mechanical stop for a second dose, drug products utilizing the same, and methods of using drug syringes with a mechanical stop for a second dose are provided. In general, a nasal drug delivery device is configured to dispense therefrom first and second doses of a drug therefrom into a nose. The drug delivery device includes a mechanical stop configured to provide a pause between the delivery of the first and second doses. During the pause, a user of the drug delivery device can move the drug delivery device from one nostril, into which the first dose was sprayed, to another nostril, into which the second dose can be sprayed. The mechanical stop is configured to hold the drug delivery device in a static delivery state.

Abstract: Various exemplary drug delivery devices with lock-out before drug delivery, drug products utilizing the same, and methods of using drug delivery devices with lock-out before drug delivery are provided. In general, a nasal drug delivery device is configured to dispense a drug therefrom into a nose and is configured to be releasably coupled to an accessory. The accessory is a separate, independent member from the drug delivery device such that in its decoupled state, the accessory is completely removed from the drug delivery device.

Abstract: Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a destruction mechanism configured to destroy drug contained in the drug delivery device. The destruction mechanism can be configured to destroy the drug before a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug contained in the drug delivery device. Alternatively or in addition, the destruction mechanism can be configured to destroy the drug after a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug remaining in the drug delivery device.

Abstract: An injection system includes a handle assembly with a handle body having an outer surface surrounding a handle body interior and a plunger extending therethrough. A tubular handle collar is telescopically received in the handle body exterior and is axially movable with respect to the handle body. A syringe housing assembly is selectively connectable to the handle assembly and includes a syringe housing and a tubular syringe sleeve telescopically received through a distal end of the syringe housing and axially movable with respect thereto. The syringe housing has an exterior side surface surrounding a syringe housing interior configured to receive at least a portion of a syringe. The syringe sleeve has a proximal end, a distal end with a skin contact surface, and a generally cylindrically-shaped outer surface.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: A device and system for training users in a proper mixing of pharmaceutical components. The devices comprise a housing including a simulated plunger, finger flange, and barrel, a removeable clip for coupling to a syringe, and a smart label for affixing to a syringe. A microcontroller receives motion information from an accelerometer and orientation information from a magnetometer to assess motion, frequency, and orientation of shaking against predetermined parameters. A vibration meter that is spaced apart from the magnetometer provides haptic feedback to the user. A display unit displays information regarding the satisfaction of the shaking parameters to the user.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: Various training devices and methods for simulating intranasal drug delivery are described. In one exemplary embodiment, a training device can include an outer sleeve, a locking sleeve coupled to the outer sleeve, a core sleeve coupled to the locking sleeve, and a plunger operatively coupled to the core sleeve. The plunger can be configured to selectively translate the core sleeve from an initial position to a first actuated position that indicates the release of a first simulated dose of a drug, and from the first actuated position to a second actuated position that indicates the release of a second simulated dose of the drug, in which the device does not contain the drug. The plunger can also be configured to rotate relative to the outer sleeve to reset the core sleeve to the initial position such that the core sleeve can be translated back to the first and second actuated positions.

Abstract: In general, drug administration devices configured to communicate with networks and external devices are provided. In an exemplary embodiment, a drug administration device is configured to adjust an operational parameter of the drug administration device based on a data packet formed from drug administration data ancillary data received from networks and/or external devices. In another example embodiment, a drug administration device is configured to scan for and establish communications with at least one external device. In another example embodiment, a method includes assessing whether to update a control program on a drug administration device from a network or external device. In another example embodiment, a system includes a first drug administration device configured to communicate with a second drug administration device to optimize a drug treatment.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: A grip accessory for a manual injection device comprises a housing having a generally hollow body for supporting a manual injection device therein. The housing comprises a distal portion comprising a first opening into which a manual injection device can be inserted, a proximal portion comprising a second opening through which a needle of the manual injection device is extendable, the proximal portion comprising a skin contacting surface at a proximal end of the device. An intermediate portion extends between the proximal and distal portions and guide means is provided on an interior surface of the distal portion for guiding a plunger rod of an injection device during delivery of an injection.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: A device (10) for simulating the dispensing of a medication into the nasal passage. The device includes a device body (12), the device body defining an extending portion (14) for inserting into the nasal passage of a user. An activation mechanism (16) movable from a start position to a dispensed position can be returned to the start position by manipulation of part of the device. Manipulation may be by rotation of a main part of the device body (12) relative to the extending portion (14).

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.