Patents by Inventor Jackie Joe Hancock
Jackie Joe Hancock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11969500Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: GrantFiled: November 10, 2021Date of Patent: April 30, 2024Assignee: Foundry Therapeutics, Inc.Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
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Publication number: 20240001095Abstract: A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system.Type: ApplicationFiled: March 3, 2023Publication date: January 4, 2024Inventors: Ling-Kang TONG, Daniela Tamar BUCHMAN, Jackie Joe HANCOCK, Nicholas TERZULLI
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Publication number: 20230136789Abstract: The present technology relates to polymer implants. In some embodiments, the polymer implant may have a volume having minimum cross-sectional dimension of 400 ?m. The polymer implant may be configured to be implanted within a mammalian body for at least 3 days without undergoing core acidification.Type: ApplicationFiled: March 5, 2021Publication date: May 4, 2023Inventors: Patrick H. Ruane, Jackie Joe Hancock, Cynthia R. Lee, Koon Kiat Teu, Daniel Boon Lim Seet, Wei Li Lee, Honglei Wang
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Patent number: 11596779Abstract: A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system.Type: GrantFiled: May 29, 2019Date of Patent: March 7, 2023Assignee: Morningside Venture Investments LimitedInventors: Ling-Kang Tong, Daniela Tamar Buchman, Jackie Joe Hancock, Nicholas Terzulli
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Publication number: 20220117885Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: ApplicationFiled: November 10, 2021Publication date: April 21, 2022Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
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Patent number: 11224570Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: GrantFiled: February 15, 2021Date of Patent: January 18, 2022Assignee: Foundry Therapeutics, Inc.Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
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Publication number: 20220001158Abstract: Described herein are drug and other active agent transdermal delivery systems and devices to deliver active agents to skin or mucosa of a subject, and methods of delivering such active agents. In particular, systems, methods, and devices are described that control the concentration and timing of active agent delivery. Such systems or devices may include a transdermal membrane and a temperature control element for heating and/or cooling a portion of the transdermal delivery system to provide pulsatile active agent delivery through the transdermal membrane.Type: ApplicationFiled: November 15, 2019Publication date: January 6, 2022Inventors: Patrick H. RUANE, Jackie Joe HANCOCK, Anubhav ARORA
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Patent number: 11202754Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: GrantFiled: April 3, 2020Date of Patent: December 21, 2021Assignee: Foundry Therapeutics, Inc.Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
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Publication number: 20210353532Abstract: The present technology relates to depot assemblies for the controlled, sustained release of a therapeutic agent. The assembly can include a depot having a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days. The assembly further includes a fixation portion coupled to the depot and configured to facilitate attachment of the depot assembly to tissue at or adjacent to the treatment site.Type: ApplicationFiled: August 27, 2019Publication date: November 18, 2021Inventors: Karun D. Naga, Hanson S. Gifford, III, Jackie Joe Hancock, Stephen W. Boyd, John Morriss, Patrick H. Ruane, Michael Feldstein, Darren Doud, Mark Deem, Koon Kiat Teu, Daniel Boon Lim Seet, Wei Li Lee, Honglei Wang
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Publication number: 20210308338Abstract: The present technology relates to polymer implants. In some embodiments, the polymer implant may have a volume having minimum cross-sectional dimension of 400 ?m. The polymer implant may be configured to be implanted within a mammalian body for at least 3 days without undergoing core acidification.Type: ApplicationFiled: August 27, 2019Publication date: October 7, 2021Inventors: Patrick H. Ruane, Jackie Joe Hancock, Koon Kiat Teu, Daniel Boon Lim Seet, Wei Li Lee, Honglei Wang
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Publication number: 20210196935Abstract: A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system.Type: ApplicationFiled: May 29, 2019Publication date: July 1, 2021Inventors: Ling-Kang TONG, Daniela Tamar BUCHMAN, Jackie Joe HANCOCK, Nicholas TERZULLI
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Publication number: 20210186868Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: ApplicationFiled: February 15, 2021Publication date: June 24, 2021Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet
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Publication number: 20210069101Abstract: The present technology relates to depot assemblies for the controlled, sustained release of a therapeutic agent. The assembly can include a depot having a therapeutic region comprising a therapeutic agent, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: ApplicationFiled: April 11, 2019Publication date: March 11, 2021Inventors: Karun D. Naga, Hanson S. Gifford, III, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koon Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet, Wei Li Lee, Nassireddin Mokarram-Dorri
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Publication number: 20200246255Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.Type: ApplicationFiled: April 3, 2020Publication date: August 6, 2020Inventors: Karun D. Naga, Stephen W. Boyd, Patrick H. Ruane, Jackie Joe Hancock, Michael Feldstein, Koot Kiat Teu, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet, Hanson S. Gifford, III
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Patent number: 10525171Abstract: A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.Type: GrantFiled: January 24, 2014Date of Patent: January 7, 2020Assignee: THE SPECTRANETICS CORPORATIONInventors: Patrick Ruane, Cameron Wilson, Steven Ummel, Arlene Alcantara, Jackie Joe Hancock, Qi Zhan
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Publication number: 20190083759Abstract: A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.Type: ApplicationFiled: November 19, 2018Publication date: March 21, 2019Inventors: Patrick RUANE, Cameron WILSON, Steve UMMEL, Arlene ALCANTARA, Jackie Joe HANCOCK, Qi ZHAN
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Publication number: 20150209555Abstract: A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.Type: ApplicationFiled: January 24, 2014Publication date: July 30, 2015Inventors: Patrick Ruane, Cameron Wilson, Steven Ummel, Arlene Alcantara, Jackie Joe Hancock, Qi Zhan