Abstract: A dispenser is disclosed for dispensing a beneficial agent to a fluid environment. The dispenser comprises an impermeable container, a reservoir, a passageway, a beneficial agent, and a polymeric agent. In operation, beneficial agent is dispensed by fluid entering the reservoir motivating the polymeric agent to undergo fluid induced transition to a viscofluid, with beneficial agent dispensed by (a) viscofluid exiting through the passageway and transporting beneficial agent concurrently therewith, or by (b) beneficial agent exhibiting an increased coefficient of diffusion in the viscofluid and diffusing therethrough to the exterior of the device. An embodiment of the invention pertaining to laminates also is disclosed as useful for manufacturing the dispenser.

Abstract: A process is disclosed for forming an outlet passageway in an osmotic dispensing device. The process comprises compressing a drug formulation into a solid mass, forming a recess in the solid mass, and then spray coating the mass with a wall forming material that surrounds the mass. The outlet passageway in the wall is formed at the recess simultaneously and automatically during the coating procedure. The passageway extends through the wall and communicates with the drug and the exterior of the device for dispensing the drug over a prolonged period of time.