Patents by Inventor Keen Chung

Keen Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular guide system peptides and uses thereof
    Patent number: 11965004
    Abstract: Disclosed are compositions comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides. Disclosed are methods of treating a subject in need thereof comprising administering to the subject in need thereof an effective amount of an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target involved in the disease process. Disclosed are methods of targeting an intracellular target comprising administering an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: April 23, 2024
    Assignee: SRI International
    Inventors: Kathlynn C. Brown, Nathan Collins, Shunzi “Susan” Li, Curtis Allred, Keen Chung, Michael McGuire
  • MOLECULAR GUIDE SYSTEM PEPTIDES AND USES THEREOF
    Publication number: 20220227823
    Abstract: Disclosed are compositions comprising an antibody conjugated to one or more molecular guidance system (MGS) peptides. Disclosed are methods of treating a subject in need thereof comprising administering to the subject in need thereof an effective amount of an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target involved in the disease process. Disclosed are methods of targeting an intracellular target comprising administering an antibody conjugated to one or more MGS peptides, wherein the antibody targets an intracellular target.
    Type: Application
    Filed: July 10, 2018
    Publication date: July 21, 2022
    Inventors: Kathlynn C. Brown, Nathan Collins, Shunzi "Susan" Li, Curtis Allred, Keen Chung, Michael McGuire
  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20220098282
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG
  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20190112357
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: May 9, 2017
    Publication date: April 18, 2019
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG