Patents by Inventor Kenneth J. Stenglein

Kenneth J. Stenglein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topiramate immunoassay
    Patent number: 5952187
    Abstract: The present invention provides a topiramate immunoassay and reagents for use in the immunoassay. In particular, topiramate is derivatized at the sulfamate moiety or the 9-carbon or 10-carbon methyl group of topiramate to add a label bound directly or through a linking group for use as a tracer (competitive analyte analog) or to add a linking group bound to a carrier for use as an immunogen to induce anti-topiramate antibodies. Immunoassay methods and kits are also provided.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: September 14, 1999
    Assignee: Oxis International, Inc.
    Inventors: Kenneth J. Stenglein, Daniel B. Cawley, Bruce E. Maryanoff, Kirk L. Sorgi
  • AZT immunoassays, derivatives, conjugates and antibodies
    Patent number: 5380825
    Abstract: This invention relates to a method for the immunoassay of AZT (3'-azido-3'-deoxythymidine), also known as zidovudine, in biological fluids such as serum, semen, plasma and urine, as well as other body fluids. The invention also includes (1) various novel analogs of AZT useful in preparing immunogens for antibodies to AZT and in preparing labeled AZT, (2) immunogens for antibodies to AZT, (3) monoclonal and polyclonal antibodies to AZT, (4) labeled AZT analogs and (5) diagnostic test kits for the immunoassay.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: January 10, 1995
    Assignee: Sigma Chemical Company
    Inventors: Kenneth J. Stenglein, Dennis M. Murray
  • ddI immunoassays, derivatives, conjugates and antibodies
    Patent number: 5221611
    Abstract: This invention relates to a method for the immunoassay of ddI (2',3'-dideoxyinosine), also known as didanosine, in biological fluids such as serum, semen, plasma and urine, as well as other body fluids. The invention also includes (1) various novel analogs of ddI useful in preparing immunogens for antibodies to ddI and in preparing labeled ddI, (2) immunogens for antibodies to ddI, (3) antibodies to ddI, (4) labeled ddI analogs and (5) diagnostic test kits for the immunoassay.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: June 22, 1993
    Assignee: Sigma Chemical Company
    Inventors: Kenneth J. Stenglein, Dennis M. Murray
  • AZT immunoassays, derivatives, conjugates and antibodies
    Patent number: 5051361
    Abstract: This invention relates to a method for the immunoassay of AZT (3'-azido-3'-deoxythymidine), also known as zidovudine, in biological fluids such as serum, semen, plasma and urine, as well as other body fluids. The invention also includes (1) various novel analogs of AZT useful in preparing immunogens for antibodies to AZT and in preparing labeled AZT, (2) immunogens for antibodies to AZT, (3) monoclonal and polylonal antibodies to AZT, (4) labeled AZT analogs and (5) diagnostic test kits for the immunoassay.
    Type: Grant
    Filed: October 19, 1988
    Date of Patent: September 24, 1991
    Assignee: Sigma Chemical Company
    Inventors: Kenneth J. Stenglein, Dennis M. Murray