Patents by Inventor Mario Rottländer

Mario Rottländer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED THIOMORPHOLINE DERIVATIVES
    Publication number: 20110294787
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: July 28, 2011
    Publication date: December 1, 2011
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • SUBSITUTED PYRIDINE DERIVATIVES
    Publication number: 20110003811
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Application
    Filed: September 14, 2010
    Publication date: January 6, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • Substituted pyridine derivatives
    Patent number: 7812020
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • Methods of using substituted morpholine derivatives
    Patent number: 7812023
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • SUBSTITUTED PYRIMIDINE DERIVATIVES
    Publication number: 20100137311
    Abstract: The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.
    Type: Application
    Filed: January 30, 2010
    Publication date: June 3, 2010
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Daniel Rodriguez Greve, Mario Rottländer
  • Substituted pyrimidine derivatives
    Patent number: 7683058
    Abstract: The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: March 23, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Nikolay Khanzhin, Daniel Rodriguez Greve, Mario Rottländer
  • Methods of using substituted morpholine derivatives
    Publication number: 20100063033
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 5, 2009
    Publication date: March 11, 2010
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Publication number: 20100063036
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 3, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted aniline derivatives
    Patent number: 7601870
    Abstract: The present invention relates to aniline derivatives of the general formula I or salts thereof, described therein, and their use.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: October 13, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7501414
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: March 10, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Heteroaryl derivates, their preparation and use
    Patent number: 7393845
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Indole derivatives
    Patent number: 7342015
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 11, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Novel indole derivatives
    Publication number: 20060258678
    Abstract: A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
    Type: Application
    Filed: June 27, 2002
    Publication date: November 16, 2006
    Inventors: Mario Rottländer, Ejner Moltzen, Ivan Mikkelsen, Thomas Tuhland, Kim Andersen, Christian Krog-Jensen
  • Method for producing Grignard compounds
    Patent number: 6899830
    Abstract: The invention relates to a process for preparing Grignard compounds of the formula I. The invention additionally relates to compounds of the formula I and to polymer-bound compounds of the formula Ia. The invention further relates to the use of the process for preparing substance libraries and to the use of the compounds of the formulae I and Ia in chemical synthesis.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: May 31, 2005
    Assignee: BASF
    Inventors: Laure Boymond, Mario Rottländer, Gerard Cahiez, Paul Knochel
  • Substituted phenyl-piperazine derivatives, their preparation and use
    Patent number: 6699864
    Abstract: The present invention provides compounds of the formula: wherein R1-R8, X, Y, Z, n and m are defined in the application. The compounds of the invention have affinity for the 5-HT1A receptor.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: March 2, 2004
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottländer, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Benzofuran derivatives, their preparation and use
    Patent number: 6492374
    Abstract: The present invention relates to benzofuran derivatives having general Formula (I) wherein A is selected from (1), (2), (3), (4) wherein Z is O or S; s is 0 or 1; q is 0 or 1; R4 is hydrogen, C1-6-alkyl, C2-6-alkenyl, C26-alkynyl, C1-6-alkyl-aryl, or C1-6-alkyl-O-aryl; D is a spacer group selected from branched or straight chain C1-6-alkylene, C2-6-alkenylene and C2-6-alkynylene; its enantiomers, and pharmaceutically acceptable acid addition salt thereof. The compounds are potently binding to the 5-HT1A receptor.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: December 10, 2002
    Assignee: H. Lundbeck A/S
    Inventors: Kim Andersen, Mario Rottländer, Klaus Peter Bøgesø, Henrik Pedersen, Thomas Ruhland, Robert Dancer
  • Method for the stereoselective production of grignard compounds and use thereof
    Patent number: 6432326
    Abstract: A process for the stereoselective preparation of Grignard compounds of the formula I and polymer-bonded compounds of the formula Ia is described. The process can be used for producing substance reference libraries and the compounds of the formulae I and Ia can be used in stereoselective chemical synthesis.
    Type: Grant
    Filed: January 2, 2001
    Date of Patent: August 13, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Laure Boymond, Mario Rottländer, Gerard Cahiez, Paul Knochel