Patents by Inventor Mark Kirby

Mark Kirby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLUCOKINASE ACTIVITY ASSAYS FOR MEASURING KINETIC AND ACTIVATION PARAMETERS
    Publication number: 20080085528
    Abstract: The subject matter disclosed and claimed herein relates to novel in vitro assays for measuring glucokinase activity and use of these assays for identifying modulators of glucokinase.
    Type: Application
    Filed: October 10, 2007
    Publication date: April 10, 2008
    Inventors: Jovita Marcinkeviciene, Kevin O'Malley, Mark Kirby, Aiying Wang, Lisa Kopcho, Ramakrishna Seethala
  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050239839
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: June 9, 2005
    Publication date: October 27, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl
  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050228021
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: June 9, 2005
    Publication date: October 13, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl
  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050038020
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: July 27, 2004
    Publication date: February 17, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl
  • Router type cutter
    Patent number: 5213452
    Abstract: A router type cutter (1) has at one end thereof a drive spigot (2) adapted to be clamped in a rotatable toolholder of a machine tool, at least one helix (3) extending part-way along the cutter (1) from the other end, onto a cutting edge of which helix (3) is brazed a tungsten carbide insert (10) having a non-linear cutting profile along its end face (12).
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: May 25, 1993
    Assignee: Technicut Limited
    Inventor: Mark Kirby