Patents by Inventor Mathilde Lorscheider

Mathilde Lorscheider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticulate prodrugs
    Patent number: 11642320
    Abstract: The present invention relates to anti-inflammatory drug formulation. Especially, this invention relates to corticosteroid prodrug nanoparticle. In a first aspect, this invention relates to a nanoparticle comprising a therapeutic agent and a surface coating material. The invention also relates to a process of manufacturing at least one nanoparticle of invention. The invention also relates to pharmaceutical composition and pharmaceutical kits.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: May 9, 2023
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAY
    Inventors: Elias Fattal, Nicolas Tsapis, Mathilde Lorscheider, Romain Canioni, Franceline Reynaud
  • NANOPARTICULATE PRODRUGS
    Publication number: 20210275462
    Abstract: Disclosed is an anti-inflammatory drug formulation, especially a corticosteroid prodrug nanoparticle. In a first aspect, a nanoparticle includes a therapeutic agent and a surface coating material. Also disclosed are a process of manufacturing at least one nanoparticle, a pharmaceutical composition, and pharmaceutical kits.
    Type: Application
    Filed: September 20, 2017
    Publication date: September 9, 2021
    Inventors: Elias FATTAL, Nicolas TSAPIS, Mathilde LORSCHEIDER, Romain CANIONI, Franceline REYNAUD
  • EXTENDED RELEASE FORMULATIONS FOR INTRA-ARTICULAR APPLICATIONS
    Publication number: 20210177824
    Abstract: The present invention relates to a pharmaceutical composition comprising an aqueous suspension of: (i) crystalline N-(3,4-dichlorophenyl)-3-(pyridin-4-yl)-7-oxabicyclo[2.2.1]heptane-2-carboxamide or a pharmaceutically acceptable salt thereof; and (ii) a surfactant comprising a water-soluble co-polymer characterized by >5% solubility in water at 25° C. The compositions provide extended release of N-(3,4-dichlorophenyl)-3-(pyridin-4-yl)-7-oxabicyclo[2.2.1] heptane-2-carboxamide, and are suitable for intra-articular injection to a joint of a patient suffering from arthritis, joint injury or cartilage injury.
    Type: Application
    Filed: November 8, 2018
    Publication date: June 17, 2021
    Inventors: Carlo Castagnoli, Andreas Fisch, Mathilde Lorscheider, Manjali Laxman Neharkar, Bernd Ulrich Riebesehl