Patents by Inventor Michael Breslav

Michael Breslav has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfamide derivative useful for the treatment of epilepsy
    Patent number: 7897636
    Abstract: The present invention is directed to novel sulfamide derivatives, pharmaceutical compositions comprising said compounds and methods for the treatment of epilepsy and related disorders comprising administering to a subject in need thereof, said compounds, either alone or as co-therapy with one or more anticonvulsant and/or anti-epileptic agents.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: March 1, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Michael Breslav, Brian Klein, Xun Li, John A. Moyer, Frank J. Villani
  • SULFAMIDE DERIVATIVE USEFUL FOR THE TREATMENT OF EPILEPSY
    Publication number: 20090176865
    Abstract: The present invention is directed to novel sulfamide derivatives, pharmaceutical compositions comprising said compounds and methods for the treatment of epilepsy and related disorders comprising administering to a subject in need thereof, said compounds, either alone or as co-therapy with one or more anticonvulsant and/or anti-epileptic agents.
    Type: Application
    Filed: August 7, 2008
    Publication date: July 9, 2009
    Inventors: Michael Breslav, Brian Klein, John A. Moyer, Frank J. Villani
  • Process for preparing peptidyl heterocyclic ketone derivatives
    Patent number: 7205384
    Abstract: The present invention relates to novel processes for the preparation of peptidyl heterocyclic ketones of the general formula (I) wherein all variables are as herein defined. The present invention further relates to novel pharmaceutical salts and processes for their preparation. The peptidyl heterocyclic ketones of formula (I) are potent and selective inhibitors of tryptase, useful for the treatment and prevention of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: April 17, 2007
    Assignee: Ortho-McNeil Pharmaceutical Inc.
    Inventors: Michael Breslav, Bruce Harris, Birdella Kenney, Thomas Maier, Armin Roessler, Frank Villani, Ulrich Weigl, Fan Zhang-Plasket, Hua Zhong
  • Process for preparing peptidyl heterocyclic ketone derivatives
    Publication number: 20050059607
    Abstract: The present invention relates to novel processes for the preparation of peptidyl heterocyclic ketones of the general formula (I) wherein all variables are as herein defined. The present invention further relates to novel pharmaceutical salts and processes for their preparation. The peptidyl heterocyclic ketones of formula (I) are potent and selective inhibitors of tryptase, useful for the treatment and prevention of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
    Type: Application
    Filed: July 29, 2004
    Publication date: March 17, 2005
    Inventors: Michael Breslav, Bruce Harris, Birdella Kenney, Thomas Maier, Armin Roessler, Frank Villani, Ulrich Weigl, Fan Zhang-Plasket, Hua Zhong