Patents by Inventor Mikael S. Thomsen

Mikael S. Thomsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11690814
    Abstract: Provided is a composition comprising suplatast tosilate or pharmaceutically acceptable derivatives thereof for use in a method of treating cough associated with interstitial lung disease, such as cough associated with pulmonary fibrosis.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: July 4, 2023
    Assignee: CONRIG PHARMA APS
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Niels Skjærbæk
  • Publication number: 20230092397
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 23, 2023
    Inventors: Peter G. NIELSEN, Mikael S. THOMSEN, Bent HØJGAARD
  • Patent number: 11478476
    Abstract: The present invention is directed to a composition comprising a buspirone metabolite, alone or in combination with a second active ingredient, for use in the treatment of movement disorders.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: October 25, 2022
    Assignee: CONTERA PHARMA APS
    Inventors: John Bondo Hansen, Mikael S. Thomsen
  • Patent number: 11426383
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 30, 2022
    Assignee: Saniona A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20210023050
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically accetpable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Application
    Filed: October 9, 2020
    Publication date: January 28, 2021
    Inventors: Peter G. NIELSEN, Mikael S. THOMSEN, Bent HØJGAARD
  • Patent number: 10828278
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: November 10, 2020
    Assignee: Saniona A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20200129478
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Application
    Filed: December 6, 2019
    Publication date: April 30, 2020
    Inventors: Peter G. NIELSEN, Mikael S. THOMSEN, Bent HØJGAARD
  • Patent number: 10632116
    Abstract: The present invention relates to the use of 5-HT1 agonists in pharmaceutical compositions, compounds and methods for treatment of movement disorders related to neurological dysfunctions. The invention is particularly relevant for treatment of patients suffering from tardive dyskinesia, Parkinson's disease and associated disorders thereof. Kits of parts comprising the 5-HT1 agonist compounds or pharmaceutical compositions according to the present invention, as well as methods of preparation are also provided by the present invention.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: April 28, 2020
    Assignee: Contera Pharma A/S
    Inventors: John Bondo Hansen, Mikael S. Thomsen
  • Patent number: 10561618
    Abstract: The present invention provides a pharmaceutical formulation for oral administration comprising an agonist of two or more of the 5-HT1B, 5-HT1D and 5-HT1F receptors, such as a triptan, e.g. zolmitriptan, in a matrix constituent with extended release characteristics, and further comprising a 5-HT1A-R agonist, such as buspirone, in a constituent with immediate-release characteristics. The special formulation is particularly well-suited for use in the treatment of movement disorders by combining the two active ingredients in a manner that achieves synergy from both the combination per se and the special release parameters of the pharmaceutical formulation, allowing for ease of administration and reducing the risk of adverse effects of each of the two active ingredients.
    Type: Grant
    Filed: April 18, 2013
    Date of Patent: February 18, 2020
    Assignee: Contera Pharma ApS
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Jens D. Mikkelsen, Peter Gudmund Nielsen, Mads Kreilgaard
  • Patent number: 10537551
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: January 21, 2020
    Assignee: Saniona A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20190254998
    Abstract: Provided is a composition comprising suplatast tosilate or pharmaceutically acceptable derivatives thereof for use in a method of treating cough associated with interstitial lung disease, such as cough associated with pulmonary fibrosis.
    Type: Application
    Filed: November 16, 2016
    Publication date: August 22, 2019
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Niels Skjærbæk
  • Patent number: 10231951
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity or an obesity associated disorder.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: March 19, 2019
    Assignee: SANIONA A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20180360804
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Inventors: Peter G. NIELSEN, Mikael S. THOMSEN, Bent HØJGAARD
  • Publication number: 20170128446
    Abstract: The present invention is directed to a composition comprising a buspirone metabolite, alone or in combination with a second active ingredient, for use in the treatment of movement disorders.
    Type: Application
    Filed: June 25, 2015
    Publication date: May 11, 2017
    Inventors: John Bondo HANSEN, Mikael S. THOMSEN
  • Patent number: 9579288
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity or an obesity associated disorder.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: February 28, 2017
    Assignee: Saniona A/S
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20160279067
    Abstract: The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity or an obesity associated disorder.
    Type: Application
    Filed: March 2, 2016
    Publication date: September 29, 2016
    Inventors: Peter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
  • Publication number: 20160058762
    Abstract: The present invention relates to the use of 5-HT1 agonists in pharmaceutical compositions, compounds and methods for treatment of movement disorders related to neurological dysfunctions. The invention is particularly relevant for treatment of patients suffering from tardive dyskinesia, Parkinson's disease and associated disorders thereof. Kits of parts comprising the 5-HT1 agonist compounds or pharmaceutical compositions according to the present invention, as well as methods of preparation are also provided by the present invention.
    Type: Application
    Filed: November 10, 2015
    Publication date: March 3, 2016
    Inventors: John Bondo Hansen, Mikael S. Thomsen
  • Patent number: 9186359
    Abstract: The present invention relates to the use of 5-HT1 agonists in pharmaceutical compositions, compounds and methods for treatment of movement disorders related to neurological dysfunctions. The invention is particularly relevant for treatment of patients suffering from tardive dyskinesia, Parkinson's disease and associated disorders thereof. Kits of parts comprising the 5-HT1 agonist compounds or pharmaceutical compositions according to the present invention, as well as methods of preparation are also provided by the present invention.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: November 17, 2015
    Assignee: Contera Pharma ApS
    Inventors: John Bondo Hansen, Mikael S. Thomsen
  • Publication number: 20150104506
    Abstract: The present invention provides a pharmaceutical formulation for oral administration comprising an agonist of two or more of the 5-HT1B, 5-HT1D and 5-HT1F receptors, such as a triptan, e.g. zolmitriptan, in a matrix constituent with extended release characteristics, and further comprising a 5-HT1A-R agonist, such as buspirone, in a constituent with immediate-release characteristics. The special formulation is particularly well-suited for use in the treatment of movement disorders by combining the two active ingredients in a manner that achieves synergy from both the combination per se and the special release parameters of the pharmaceutical formulation, allowing for ease of administration and reducing the risk of adverse effects of each of the two active ingredients.
    Type: Application
    Filed: April 18, 2013
    Publication date: April 16, 2015
    Applicant: CONTERA PHARMA APS
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Jens D. Mikkelsen, Peter Gudmund Nielsen, Mads Kreilgaard
  • Publication number: 20150031765
    Abstract: The present invention relates to a compound with the core structure of formula (I), or pharmaceutically acceptable salts or esters, solvates, or prodrugs thereof, for use in the treatment of cognitive impairment in a mammal. The compound is preferably isosteviol or steviol, or pharmaceutically acceptable salts or esters, solvates, or prodrugs thereof.
    Type: Application
    Filed: October 14, 2014
    Publication date: January 29, 2015
    Inventors: Maurice Robert CROSS, Mikael S. THOMSEN, Jenny HAGGLOF