Patents by Inventor Nicholas V. Perricone
Nicholas V. Perricone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156900Abstract: The present disclosure generally relates to systems and methods for delivering humanin and/or other peptides to a subject. In some cases, these may be used for treating or preventing aging skin, or for other diseases. Non-limiting examples of other peptides include mitochondrial-derived peptides such as HNG or MOTS-c. In addition, certain embodiments are generally directed to treatments that can be delivered using topical compositions applied to the skin. For example, in some cases, the composition includes lecithin and/or other components that may facilitate delivery through the skin. Further, certain embodiments may include active ingredients such as tributyrin or 2,6-dimethyl-L-tyrosine, which may interact with humanin or other peptides. Compositions such as these may be used in certain embodiments, for example, to reduce inflammation within the skin, or as an anti-aging treatment, etc.Type: ApplicationFiled: October 28, 2022Publication date: May 16, 2024Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Patent number: 11980651Abstract: The present disclosure generally relates to compositions comprising dihexa and methods for making or using said compositions. In some aspects, the compositions disclosed herein may comprise one or more additional active ingredients, including lipoic acid, spadin peptide, and/or phenyl-N-tert-butylnitrone. Compositions such as these may be used in certain embodiments, for example, to enhances a subject's hearing or to treat a hearing disorder, etc. In some embodiments, the compositions are topical compositions configured to treat hearing loss via administration, e.g., to the skin behind the outer ear or directly to the eardrum of a subject, etc. In some cases, the compositions disclosed herein may comprise one or more excipients to aid in transdermal delivery. For instance, in certain embodiments, the compositions comprise lecithin and/or other components that may facilitate delivery through the skin.Type: GrantFiled: June 21, 2023Date of Patent: May 14, 2024Assignee: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Publication number: 20240139107Abstract: The present disclosure generally relates to systems and methods for treating or preventing aging skin or other indications. For example, some aspects are generally directed to systems and methods for administering a conjugate of a dendrimer and A-acetyl-L-cysteine to a subject, e.g., to the skin of a subject. For example, in one set of embodiments, the conjugate may be applied to aging skin, e.g., to treat or reverse the appearance of aging in the skin. Surprisingly, even though such conjugates can be relatively large (e.g., greater than 3 or 4 nm in diameter) and normally difficult to administer, formulations such as those described herein are effective at facilitating transdermal drug delivery of the conjugates. In addition, in addition to aging skin, other indications may be treated in certain aspects, for example, if the subject has or is at risk of a brain injury or a neurological disorder.Type: ApplicationFiled: March 7, 2022Publication date: May 2, 2024Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Publication number: 20240122888Abstract: The present disclosure generally relates to systems and methods for delivering lactate and phenylalanine, and/or N-lactoyl-phenylalanine and/or other N-lactoyl amino acids to a subject. In some cases, these may be used for appetite control, weight loss, treating or preventing obesity, or for other metabolic-related diseases. In addition, certain embodiments are generally directed to treatments that can be delivered using topical compositions applied to the skin. For example, in some cases, the composition includes lecithin and/or other components that may facilitate delivery through the skin. Further, certain embodiments may include active ingredients such as tributyrin or 2,6-dimethyl-L-tyrosine, which may interact with lactate and phenylalanine, and/or N-lactoyl-phenylalanine and/or other N-lactoyl amino acids. Compositions such as these may be used in certain embodiments, for example, to suppress a subject's appetite, etc.Type: ApplicationFiled: March 2, 2023Publication date: April 18, 2024Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Publication number: 20240122884Abstract: The present disclosure generally relates to systems and methods for delivering N-lactoyl-phenylalanine and/or other N-lactoyl amino acids to a subject. In some cases, these may be used for appetite control, weight loss, treating or preventing obesity, or for other metabolic-related diseases. In addition, certain embodiments are generally directed to treatments that can be delivered using topical compositions applied to the skin. For example, in some cases, the composition includes lecithin and/or other components that may facilitate delivery through the skin. Further, certain embodiments may include active ingredients such as tributyrin or 2,6-dimethyl-L-tyrosine, which may interact with N-lactoyl-phenylalanine and/or other N-lactoyl amino acids. Compositions such as these may be used in certain embodiments, for example, to suppress a subject's appetite, etc.Type: ApplicationFiled: October 3, 2022Publication date: April 18, 2024Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Patent number: 11934046Abstract: A laser protection eyewear lens includes a lens substrate comprising an embedded wavelength filter having a first filter function, and a multi-layer dielectric filter applied to at least one of an inside and an outside surface of the lens substrate that comprises a second filter function having at least one center wavelength and bandwidth. The first filter function of the embedded wavelength filter and the second filter function of the multilayer dielectric filter produce a combined filter function that attenuates light reflecting off the multi-layer dielectric filter.Type: GrantFiled: April 10, 2023Date of Patent: March 19, 2024Assignee: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kristin A. Rauschenbach
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Publication number: 20230403780Abstract: A plasma engine includes a plasma source that generates ions from molecular gas species received at a gas input where at least some of the ions generated are atomic species ions. An ion extractor is configured to extract ions from the plasma source with an electric field. A housing comprising a recombination region receives ions extracted from the ion extractor. At least some of the atomic species ions recombine into molecular species in the housing, thereby releasing energy for thrust.Type: ApplicationFiled: October 28, 2022Publication date: December 14, 2023Applicant: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kurt Rauschenbach, Matthew Partlow
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Publication number: 20230251507Abstract: A laser protection eyewear lens includes a lens substrate comprising an embedded wavelength filter having a first filter function, and a multi-layer dielectric filter applied to at least one of an inside and an outside surface of the lens substrate that comprises a second filter function having at least one center wavelength and bandwidth. The first filter function of the embedded wavelength filter and the second filter function of the multilayer dielectric filter produce a combined filter function that attenuates light reflecting off the multi-layer dielectric filter.Type: ApplicationFiled: April 10, 2023Publication date: August 10, 2023Applicant: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kristin A. Rauschenbach
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Patent number: 11644690Abstract: A laser protection eyewear lens includes a lens substrate comprising an embedded wavelength filter having a first filter function, and a multi-layer dielectric filter applied to at least one of an inside and an outside surface of the lens substrate that comprises a second filter function having at least one center wavelength and bandwidth. The first filter function of the embedded wavelength filter and the second filter function of the multilayer dielectric filter produce a combined filter function that attenuates light reflecting off the multi-layer dielectric filter.Type: GrantFiled: January 5, 2021Date of Patent: May 9, 2023Assignee: PerriGuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kristin A. Rauschenbach
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Patent number: 11510307Abstract: A plasma engine includes a plasma source that generates ions from molecular gas species received at a gas input where at least some of the ions generated are atomic species ions. An ion extractor is configured to extract ions from the plasma source with an electric field. A housing comprising a recombination region receives ions extracted from the ion extractor. At least some of the atomic species ions recombine into molecular species in the housing, thereby releasing energy for thrust.Type: GrantFiled: May 8, 2022Date of Patent: November 22, 2022Inventors: Nicholas V. Perricone, Kurt Rauschenbach, Matthew Partlow
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Publication number: 20220361312Abstract: A plasma engine includes a plasma source that generates ions from molecular gas species received at a gas input where at least some of the ions generated are atomic species ions. An ion extractor is configured to extract ions from the plasma source with an electric field. A housing comprising a recombination region receives ions extracted from the ion extractor. At least some of the atomic species ions recombine into molecular species in the housing, thereby releasing energy for thrust.Type: ApplicationFiled: May 8, 2022Publication date: November 10, 2022Applicant: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kurt Rauschenbach, Matthew Partlow
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Patent number: 11351129Abstract: The present invention generally relates to systems and methods for treating vitiligo. In one set of embodiments, the present invention comprises a composition comprising pyruvic acid and/or a pyruvate salt. The composition may be formulated for application to the skin of a subject, for instance, as a gel, lotion, cream, ointment, soap, or stick. In some cases, the composition may comprise a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present as a liquid crystal, and/or in liposomes, micelles, or other vesicles. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.Type: GrantFiled: May 20, 2020Date of Patent: June 7, 2022Assignee: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Patent number: 11129848Abstract: Embodiments described herein generally relate to medicinal compositions (e.g., compositions comprising an active pharmaceutical agent) such as those comprising liquid hydrogen and/or hydrogen gas. In certain embodiments, the composition comprises hydrogen and/or noble gas(es) in a medicinal composition, for example, within the aqueous phase (e.g., dissolved). For example, in some cases, the medicinal composition may comprise an active pharmaceutical ingredient and hydrogen (H2) and/or noble gas(es). The noble gas may be, for example, xenon, argon, or the like. In some embodiments, the hydrogen and/or the noble gas(es) may infuse with the composition (e.g., such that at least a portion of the hydrogen gas and/or noble gas(es) is dissolved within the composition). Such compositions comprising hydrogen gas and/or noble gas(es) may be useful, for example, for the treatment of animal and human diseases, for improvement in athletic performance, for the enhancement of the overall health of a subject, or the like.Type: GrantFiled: August 8, 2017Date of Patent: September 28, 2021Assignee: Perricone Hydrogen Water Company, LLCInventor: Nicholas V. Perricone
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Patent number: 11123365Abstract: Embodiments described herein generally relate to liquids, such as aqueous solutions, that contain hydrogen gas and palmitoylethanolamide. In certain cases, the liquids may also include active pharmaceutical agents (e.g., cannabinoids), noble gases, and/or other additives. Such liquids may be useful, for example, for increasing a subject's physical energy levels, for improvement in athletic performance, for the enhancement of the overall health of a subject, or the like. Some embodiments relate to liquids disposed within a container (e.g., a sealed container), such that the liquid comprises hydrogen gas and palmitoylethanolamide dissolved or otherwise contained (e.g., suspended and/or infused) in the liquid. The liquids (e.g., aqueous solutions) described herein may be orally administered to a subject (e.g., drunk by a subject). In certain embodiments, the hydrogen gas and/or palmitoylethanolamide may be present in the liquid at a particular concentration (e.g., a physiologically relevant concentration).Type: GrantFiled: November 18, 2019Date of Patent: September 21, 2021Assignee: Perricone Hydrogen Water Company, LLCInventor: Nicholas V. Perricone
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Publication number: 20210271113Abstract: A laser protection eyewear lens includes a lens substrate comprising an embedded wavelength filter having a first filter function, and a multi-layer dielectric filter applied to at least one of an inside and an outside surface of the lens substrate that comprises a second filter function having at least one center wavelength and bandwidth. The first filter function of the embedded wavelength filter and the second filter function of the multilayer dielectric filter produce a combined filter function that attenuates light reflecting off the multi-layer dielectric filter.Type: ApplicationFiled: January 5, 2021Publication date: September 2, 2021Applicant: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kristin A. Rauschenbach
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Publication number: 20210260001Abstract: The present invention generally relates to systems and methods for treating vitiligo and related conditions. In some embodiments, a composition comprising phloroglucinol and/or related compounds, such as benzenetriols, phlorotannins, or algae extract, is applied to the skin. The composition may be formulated for application to the skin of a subject, for instance, as a gel, lotion, cream, ointment, soap, or stick. The composition may also comprise a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present as a liquid crystal, and/or in liposomes, micelles, or other vesicles. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.Type: ApplicationFiled: February 4, 2021Publication date: August 26, 2021Applicant: Transdermal Biotechnology, Inc.Inventors: Nicholas V. Perricone, Peter T. Pugliese
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Publication number: 20210145864Abstract: Embodiments described herein generally relate to liquids, such as aqueous solutions, that contain hydrogen gas and palmitoylethanolamide. In certain cases, the liquids may also include active pharmaceutical agents (e.g., cannabinoids), noble gases, and/or other additives. Such liquids may be useful, for example, for increasing a subject's physical energy levels, for improvement in athletic performance, for the enhancement of the overall health of a subject, or the like. Some embodiments relate to liquids disposed within a container (e.g., a sealed container), such that the liquid comprises hydrogen gas and palmitoylethanolamide dissolved or otherwise contained (e.g., suspended and/or infused) in the liquid. The liquids (e.g., aqueous solutions) described herein may be orally administered to a subject (e.g., drunk by a subject). In certain embodiments, the hydrogen gas and/or palmitoylethanolamide may be present in the liquid at a particular concentration (e.g., a physiologically relevant concentration).Type: ApplicationFiled: November 18, 2019Publication date: May 20, 2021Applicant: Perricone Hydrogen Water Company, LLCInventor: Nicholas V. Perricone
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Publication number: 20210093592Abstract: The present invention generally relates to systems and methods for treating vitiligo. In one set of embodiments, the present invention comprises a composition comprising pyruvic acid and/or a pyruvate salt. The composition may be formulated for application to the skin of a subject, for instance, as a gel, lotion, cream, ointment, soap, or stick. In some cases, the composition may comprise a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present as a liquid crystal, and/or in liposomes, micelles, or other vesicles. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.Type: ApplicationFiled: May 20, 2020Publication date: April 1, 2021Applicant: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone
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Patent number: 10895761Abstract: A laser protection eyewear lens includes a lens substrate comprising an embedded wavelength filter having a first filter function, and a multi-layer dielectric filter applied to at least one of an inside and an outside surface of the lens substrate that comprises a second filter function having at least one center wavelength and bandwidth. The first filter function of the embedded wavelength filter and the second filter function of the multilayer dielectric filter produce a combined filter function that attenuates light reflecting off the multi-layer dielectric filter.Type: GrantFiled: January 20, 2017Date of Patent: January 19, 2021Assignee: PerriQuest Defense Research Enterprises, LLCInventors: Nicholas V. Perricone, Kristin A. Rauschenbach
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Patent number: 10695306Abstract: The present invention generally relates to systems and methods for treating vitiligo. In one set of embodiments, the present invention comprises a composition comprising pyruvic acid and/or a pyruvate salt. The composition may be formulated for application to the skin of a subject, for instance, as a gel, lotion, cream, ointment, soap, or stick. In some cases, the composition may comprise a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present as a liquid crystal, and/or in liposomes, micelles, or other vesicles. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.Type: GrantFiled: April 23, 2019Date of Patent: June 30, 2020Assignee: Transdermal Biotechnology, Inc.Inventor: Nicholas V. Perricone