Patents by Inventor Nigel L. Webb

Nigel L. Webb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and Methods for Computing Measurements for Mitochondrial Diseases
    Publication number: 20210375467
    Abstract: This disclosure is directed to methods of methods of computing a composite measurement comprising employing two or more sub-instruments to measure one or more clinical symptoms of mitochondrial dysfunction or mitochondrial disease. This disclosure is also directed to methods of assessing and managing a subject with mitochondrial dysfunction or mitochondrial disease using a composite measurement.
    Type: Application
    Filed: June 26, 2019
    Publication date: December 2, 2021
    Applicants: RIBONOVA INC., The Children's Hospital of Philadelphia
    Inventors: Marni J. Falk, Nigel L. Webb, Shana E. McCormack, Eric C. Yuen, Zarazuela Zolkipli-Cunningham, Anthony W. Ford-Hutchinson
  • Methods of Treating Mitochondrial Dysfunction
    Publication number: 20210283072
    Abstract: This disclosure is directed to methods of treating or preventing mitochondrial dysfunction or mitochondrial disease in a subject comprising administration of probucol, or a pharmaceutically acceptable salt thereof. This disclosure is also directed to methods of diagnosing genetic mitochondrial disease in a subject prior to and in association with said treatment or prevention. This disclosure is also directed to methods of assessing and managing a subject with mitochondrial dysfunction or mitochondrial disease using a composite measurement.
    Type: Application
    Filed: June 26, 2019
    Publication date: September 16, 2021
    Applicant: RIBONOVA INC.
    Inventors: Marni J. Falk, Shana E. McCormack, Zaraxuela Zolkipli-Cunningham, Nigel L. Webb, Eric C. Yuen, Anthony W. Ford-Hutchinson
  • Nuclions and ribocapsids
    Patent number: 9969765
    Abstract: The invention relates to an isolated nuclion having (i) a core nucleic acid, and (ii) one or more ribocapsids each including a polymer of two or more ribocapsid subunits, wherein said ribocapsid subunits include nucleic acid. The invention also relates to a method for manufacturing an isolated nuclion.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: May 15, 2018
    Inventors: Nigel L. Webb, Howard B. Gamper
  • Nuclions and Ribocapsids
    Publication number: 20130267695
    Abstract: The invention relates to an isolated nuclion having (i) a core nucleic acid, and (ii) one or more ribocapsids each including a polymer of two or more ribocapsid subunits, wherein said ribocapsid subunits include nucleic acid. The invention also relates to a method for manufacturing an isolated nuclion.
    Type: Application
    Filed: November 7, 2011
    Publication date: October 10, 2013
    Inventors: Nigel L. Webb, Howard B. Gamper
  • Fatty acid-pharmaceutical agent conjugates
    Patent number: 8314077
    Abstract: The invention provides conjugates of fatty acids and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: November 20, 2012
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Nigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
  • FATTY ACID-ANTICANCER CONJUGATES AND USES THEREOF
    Publication number: 20080125380
    Abstract: The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided.
    Type: Application
    Filed: June 21, 2007
    Publication date: May 29, 2008
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: Nigel L. Webb, Matthews O. Bradley, Forrest Anthony, Mark Fisher
  • Fatty acid-anticancer conjugates and uses thereof
    Patent number: 7235583
    Abstract: The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided.
    Type: Grant
    Filed: March 9, 1999
    Date of Patent: June 26, 2007
    Assignee: Luitpold Pharmaceuticals, Inc.,
    Inventors: Nigel L. Webb, Matthews O. Bradley, Forrest Anthony, Mark Fisher
  • DHA-pharmaceutical agent conjugates of taxanes
    Patent number: 7199151
    Abstract: The invention provides conjugates of cis-docosahexaenoic acid and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: April 3, 2007
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Victor E. Shashoua, Charles E. Swindell, Nigel L. Webb, Matthews O. Bradley
  • DHA-pharmaceutical agent conjugates of taxanes
    Publication number: 20040180949
    Abstract: The invention provides conjugates of cis-docosahexaenoic acid and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Application
    Filed: July 14, 2003
    Publication date: September 16, 2004
    Applicant: Protarga, Inc.
    Inventors: Victor E. Shashoua, Charles E. Swindell, Nigel L. Webb, Matthews O. Bradley
  • Fatty acid-pharmaceutical agent conjugates
    Publication number: 20040106589
    Abstract: The invention provides conjugates of fatty acids and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Application
    Filed: June 5, 2003
    Publication date: June 3, 2004
    Applicant: Protarga Pharmaceuticals, Inc.
    Inventors: Nigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
  • Dha-pharmaceutical agent conjugates to improve tissue selectivity
    Patent number: 6602902
    Abstract: The invention provides conjugates of cis-docosahexaenoic acid and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: August 5, 2003
    Assignee: Protarga, Inc.
    Inventors: Victor E. Shashoua, Charles E. Swindell, Nigel L. Webb, Matthews O. Bradley
  • Method of treating a liver disorder with fatty acid-antiviral agent conjugates
    Patent number: 6576636
    Abstract: The invention provides conjugates of fatty acids and antiviral agents useful in treating liver disorders.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: June 10, 2003
    Assignee: Protarga, Inc.
    Inventors: Nigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
  • Nucleoside analog compositions and uses thereof
    Publication number: 20020025943
    Abstract: The invention provides compositions that include conjugates of a carrier molecule, preferably cis-docosahexaenoic acid, and 2′,3′-dideoxycytidine. The conjugates are useful in treating viral infections, especially retroviral infections, and particularly reservoirs of viral infection in peripheral T cells and central nervous system manifestations thereof.
    Type: Application
    Filed: September 6, 2001
    Publication date: February 28, 2002
    Inventors: Matthews O. Bradley, Charles S. Swindell, Nigel L. Webb, Victor Shashoua
  • Fatty acid-pharmaceutical agent conjugates
    Publication number: 20010002404
    Abstract: The invention provides conjugates of fatty acids and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Application
    Filed: December 5, 2000
    Publication date: May 31, 2001
    Inventors: Nigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
  • Clozapine compositions and uses thereof
    Patent number: 6197764
    Abstract: The invention provides compositions that include conjugates of a fatty acid molecule, preferably cis-docosahexaenoic acid, and clozapine. The conjugates are useful in treating psychological disorders such as schizophrenia.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: March 6, 2001
    Assignee: Protarga, Inc.
    Inventors: Matthews O. Bradley, Victor E. Shashoua, Charles S. Swindell, Nigel L. Webb
  • Taxanes
    Patent number: 6080877
    Abstract: The invention provides taxanes that are conjugates of cis-docosahexaenoic acid and taxotere. The conjugates are useful in treating cancer.
    Type: Grant
    Filed: June 3, 1997
    Date of Patent: June 27, 2000
    Assignee: Neuromedica, Inc.
    Inventors: Charles S. Swindell, Victor E. Shashoua, Matthews O. Bradley, Nigel L. Webb
  • Cholinergic compositions and uses thereof
    Patent number: 5977174
    Abstract: The invention provides compositions that include conjugates of a cholinergic agent and a fatty acid, preferably cis-docosahexaenoic acid. The conjugates are useful in treating disorders resulting from cerebral ischemia including stroke.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: November 2, 1999
    Assignee: Neuromedica, Inc.
    Inventors: Matthews O. Bradley, Victor E. Shashoua, Charles S. Swindell, Nigel L. Webb
  • Fatty acid-antipsychotic compositions and uses thereof
    Patent number: 5955459
    Abstract: The invention provides compositions that include conjugates of a fatty acid molecule, preferably cis-docosahexaenoic acid, and antipsychotic agents. The conjugates are usefull in treating psychotic conditions such as schizophrenia.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: September 21, 1999
    Assignee: Neuromedica, Inc.
    Inventors: Matthews O. Bradley, Victor E. Shashoua, Charles S. Swindell, Nigel L. Webb
  • Taxane compounds and compositions
    Patent number: 5919815
    Abstract: The invention provides taxanes that are conjugates of cis-docosahexaenoic acid and paclitaxel. The conjugates are useful in treating cancer.
    Type: Grant
    Filed: May 22, 1996
    Date of Patent: July 6, 1999
    Assignee: Neuromedica, Inc.
    Inventors: Matthews O. Bradley, Victor E. Shashoua, Charles S. Swindell, Nigel L. Webb
  • DHA-pharmaceutical agent conjugates of taxanes
    Patent number: 5795909
    Abstract: The invention provides conjugates of cis-docosahexaenoic acid and taxanes useful in treating cell proliferative disorders. Conjugates of paclitaxel and docetaxel are preferred.
    Type: Grant
    Filed: May 22, 1996
    Date of Patent: August 18, 1998
    Assignee: Neuromedica, Inc.
    Inventors: Victor E. Shashoua, Charles S. Swindell, Nigel L. Webb, Matthews O. Bradley