Patents by Inventor Pramod M. Kotwal

Pramod M. Kotwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080260813
    Abstract: The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.
    Type: Application
    Filed: October 30, 2007
    Publication date: October 23, 2008
    Inventors: Madhav S. Thakur, Pramod M. Kotwal, Irwin S. Gibbs
  • Patent number: 7125560
    Abstract: The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: October 24, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Madhav S. Thakur, Pramod M. Kotwal, Irwin S. Gibbs
  • Publication number: 20040156901
    Abstract: The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 12, 2004
    Inventors: Madhav S. Thakur, Pramod M. Kotwal, Irwin S. Gibbs
  • Patent number: 6696091
    Abstract: The invention is directed to a pharmaceutical composition of topiramate an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: February 24, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Madhav S. Thakur, Pramod M. Kotwal, Irwin S. Gibbs
  • Publication number: 20020064563
    Abstract: The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.
    Type: Application
    Filed: March 1, 1999
    Publication date: May 30, 2002
    Inventors: MADHAV S. THAKUR, PRAMOD M. KOTWAL, IRWIN S. GIBBS
  • Patent number: 5645858
    Abstract: This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle.
    Type: Grant
    Filed: December 7, 1995
    Date of Patent: July 8, 1997
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Pramod M. Kotwal, Stephen A. Howard
  • Patent number: 5474786
    Abstract: This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: December 12, 1995
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Pramod M. Kotwal, Stephen A. Howard
  • Patent number: 5395626
    Abstract: This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle.
    Type: Grant
    Filed: March 23, 1994
    Date of Patent: March 7, 1995
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Pramod M. Kotwal, Stephen A. Howard
  • Patent number: 4665098
    Abstract: A dosage of N-(4-hydroxyphenyl)retinamide, also known as fenretimide, of the following formula: ##STR1## with increased bioavailability comprising corn oil and a non-ionic surfactant. The formulation if useful in the treatment of breast or bladder cancer, psoriasis and acne.
    Type: Grant
    Filed: March 28, 1985
    Date of Patent: May 12, 1987
    Assignee: McNeilab, Inc.
    Inventors: Irwin S. Gibbs, Pramod M. Kotwal
  • Patent number: 4246399
    Abstract: Complexes of the formula:A.X.sub.nwherein A represents doxorubicin; wherein X represents Ca.sup.++, Mg.sup.++, Zn.sup.++, or Ni.sup.++ ; and wherein n represents one or two having enhanced stability are disclosed.The above-described compounds are inorganic complexes of a well-known and regulatory approved compound, doxorubicin, useful in the treatment of a variety of carcinomas. These complexes offer enhanced stability over doxorubicin per se.
    Type: Grant
    Filed: March 21, 1977
    Date of Patent: January 20, 1981
    Assignee: INTERx Research Corporation
    Inventors: Takeru Higuchi, Pramod M. Kotwal