Patents by Inventor Prasad Pinnamaraju

Prasad Pinnamaraju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained release formulation containing three different types of polymers and tablet formed therefrom
    Patent number: 6346268
    Abstract: Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent gelling polymer such as an alginate component, (2) an enteric polymer component, such as Eudragit® L or S, and (3) a pH independent gelling polymer, such as hydroxy propyl methyl cellulose or polyethylene oxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: February 12, 2002
    Assignee: Duramed Pharmaceuticals, Inc.
    Inventors: Guohua Zhang, Prasad Pinnamaraju, Muhammad Ali
  • Water insoluble polymer based sustained release formulation
    Patent number: 6251430
    Abstract: Sustained release drug formulations contain the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) water insoluble polymer, such as ethyl cellulose, (2) pH dependent gelling polymer, such as sodium alginate, and (3) a pH independent gelling polymer, such as hydroxypropyl methylcellulose. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: June 26, 2001
    Inventors: Guohua Zhang, Prasad Pinnamaraju, Muhammad A. Ali
  • Sustained release formulation containing three different types of polymers and tablet formed therefrom
    Patent number: 6083532
    Abstract: Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent gelling polymer such as an alginate component, (2) an enteric polymer component, such as Eudragit.RTM. L or S, and (3) a pH independent gelling polymer, such as hydroxy propyl methyl cellulose or polyethylene oxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: July 4, 2000
    Assignee: Duramed Pharmaceuticals, Inc.
    Inventors: Guohua Zhang, Prasad Pinnamaraju, Muhammad Ali
  • Sustained release formulation containing three different types of polymers
    Patent number: 5695781
    Abstract: Verapamil depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) an alginate component, such as sodium alginate, (2) an enteric polymer component, such as methacrylic acid copolymer, and (3) a pH independent gelling polymer, such as hydroxypropyl methylcellulose or polyethyleneoxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: December 9, 1997
    Assignee: Hallmark Pharmaceuticals, Inc.
    Inventors: Guohua Zhang, Prasad Pinnamaraju
  • Process to manufacture micronized nifedipine granules for sustained release medicaments
    Patent number: 5543099
    Abstract: The subject invention is a process to manufacture a sustained release pharmaceutical tablet. The process includes granulation of inactive ingredients, such as hydroxypropyl cellulose, with active ingredients, such as nifedipine; followed by micronization of the granules. Additional granulation of further active or inactive ingredients is done with or without the micronized granules formed in the first step. All of the granules are then dried if necessary, lubricated, and compressed into tablets which slowly release the active ingredient over a controlled length of time.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: August 6, 1996
    Assignee: Hallmark Pharmaceutical, Inc.
    Inventors: Guohua Zhang, Prasad Pinnamaraju