Abstract: There is provided a method for mediating the flow of messages in a computer network having a mediation architecture that includes a plurality of logical nodes in a cubic mediation arrangement. The method comprises handing over one or more mediation tasks between a donor mediator module and a recipient mediator module in response to a change request while maintaining system invariants.

Abstract: There is provided a method for mediating the flow of messages in a computer network having a mediation architecture that includes a plurality of logical nodes arranged in a logical mediation cycle. The method provides algorithms for: handing mediation tasks over between mediator nodes; reconfiguring the logical topology of the mediation architecture in response to a change request while maintaining system invariants; and refining the structure of the mediation architecture by adding whole subnetworks in place of single nodes. The method also addresses failure detection and recovery.

Abstract: The present invention relates, in general, to a method of attaching a biopolymer to a solid support and, in particular, to a method of attaching a nucleic acid to a glass surface, and to reagents suitable for use in such a method. The invention further relates to the product produced by the present method and to kits comprising same.