Patents by Inventor Richard F. Hector

Richard F. Hector has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating bacterial meningitis with anti-tumor necrosis factor antibody
    Patent number: 5616321
    Abstract: Bacterial meningitis infection in a mammal is treated by intravenous infusion of a therapeutically effective amount of a monoclonal antibody which binds to tumor necrosis factor alpha and an antibiotic. Treatment can be initiated up to five hours after bacterial challenge and the antibiotic is preferably selected from cephalosporins and aminoglycosides.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: April 1, 1997
    Assignee: Bayer Corporation
    Inventors: Richard F. Hector, Michael S. Collins
  • Antimycotic compositions of nikkomycin compounds and azole antimycotics
    Patent number: 5330976
    Abstract: Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: July 19, 1994
    Assignee: Miles Inc.
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Antimycotic compositions of nikkomycin compounds and azole antimycotics
    Patent number: 5194427
    Abstract: Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: April 29, 1992
    Date of Patent: March 16, 1993
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Nikkomycin derivatives
    Patent number: 5149795
    Abstract: The nikkomycin compound possessing antimycotic activity and having the following structure: ##STR1##
    Type: Grant
    Filed: March 25, 1991
    Date of Patent: September 22, 1992
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Antimycotic compositions of nikkomycin compounds and azole antimycotics
    Patent number: 5134126
    Abstract: Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: January 17, 1992
    Date of Patent: July 28, 1992
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Antimycotic compositions of nikkomycin compounds and azole antimycotics
    Patent number: 5096889
    Abstract: Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: January 14, 1991
    Date of Patent: March 17, 1992
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Nikkomycin derivatives
    Patent number: 5091375
    Abstract: Nikkomycin derivatives have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: January 12, 1990
    Date of Patent: February 25, 1992
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Blempel
  • Synergistic fungicidal composition
    Patent number: 5030619
    Abstract: A fungicidal composition comprising a nikkomycin and an echinocandin B. Method of treating a fungal infection comprising administering therapeutically effective amounts of a combination of the nikkomycin and the echinocandin B. Composition and method are especially useful in treating infections of filamentous fungi. Combination of nikkomycin Z and cilofungin found to be synergistic against aspergillosis.
    Type: Grant
    Filed: April 16, 1990
    Date of Patent: July 9, 1991
    Assignee: Miles Inc.
    Inventor: Richard F. Hector
  • Method for treating fungal infections with nikkomycin derivatives
    Patent number: 5019560
    Abstract: A method of treating a mammal infected with a dimorphic, highly chitinous fungi, the method comprising administering to the mammal therapeutically effective amounts of a nikkomycin derivative having the following structure: ##STR1##
    Type: Grant
    Filed: October 3, 1988
    Date of Patent: May 28, 1991
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Antimycotic compositions of nikkomycin compounds and azole antimycotica
    Patent number: 5006513
    Abstract: Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a snyergistic anti-fungal effect.
    Type: Grant
    Filed: November 29, 1989
    Date of Patent: April 9, 1991
    Assignee: Miles Inc.
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Nikkomycin derivatives, antimycotic compositions of nikkomycin derivatives and azole antimycotics
    Patent number: 4914087
    Abstract: Nikkomycin derivatives have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: April 3, 1990
    Assignee: Bayer AG
    Inventors: Richard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
  • Use of nikkomycin compounds to treat infections of dimorphic, highly chitinous fungi
    Patent number: 4851389
    Abstract: Method of treating an infection of dimorphic, highly chitinous fungi, the method comprising administering therapeutically effective amounts of a nikkomycin or derivative thereof. Treatment is especially suited for infections of medically significant fungi having cell walls with about 10-20% by weight chitin in the parasitic phase. Such fungi include Coccidiodes immitis, Histoplasma capsulatum, Blastomyces dermatitidis, and Paracoccidiodes brasiliensis.
    Type: Grant
    Filed: July 20, 1987
    Date of Patent: July 25, 1989
    Assignee: Miles Laboratories, Inc.
    Inventor: Richard F. Hector