Patents by Inventor Rifat Pamukcu

Rifat Pamukcu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising red cell-derived microparticles and method of treating excessive bleeding
    Patent number: 11241457
    Abstract: The disclosure provides a composition comprising red cell-derived microparticles (RMPs) demonstrating acetylcholine esterase (AchE) activity of less than 350 pmol/min/106 particles/uL. The disclosure further provides a method of treating excessive bleeding comprising administering the composition to a subject.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: February 8, 2022
    Assignee: RxMP Therapeutics, Inc.
    Inventors: Yeon S. Ahn, Wenche Jy, Lawrence L. Horstman, Rifat Pamukcu
  • RMP COMPOSITION AND METHODS OF USE
    Publication number: 20190321406
    Abstract: The disclosure provides a composition comprising red cell-derived microparticles (RMPs) demonstrating clinically advantageous characteristics.
    Type: Application
    Filed: November 29, 2017
    Publication date: October 24, 2019
    Inventors: Yeon S. Ahn, Wenche Jy, Lawrence L. Horstman, Rifat Pamukcu
  • MANAGING OSTEOPOROSIS WITH HMW PEG
    Publication number: 20190015353
    Abstract: The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.
    Type: Application
    Filed: August 10, 2018
    Publication date: January 17, 2019
    Applicants: MIDWAY PHARMACEUTICALS, INC., BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Rifat PAMUKCU, Laura Rae McCABE
  • Managing osteoporosis with HMW PEG
    Patent number: 10045949
    Abstract: The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 14, 2018
    Assignees: MIDWAY PHARMACEUTICALS, INC, BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Rifat Pamukcu, Laura Rae McCabe
  • MANAGING OSTEOPOROSIS WITH HMW PEG
    Publication number: 20160000730
    Abstract: The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 7, 2016
    Applicants: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY, MIDWAY PHARMACEUTICALS, INC.
    Inventors: Rifat PAMUKCU, Laura Rae MCCABE
  • Method of inhibiting neoplastic cells with indole derivatives
    Patent number: 7115647
    Abstract: A method for inhibiting neoplastic cells and related conditions by exposing them to substituted indole derivatives.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: October 3, 2006
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Rifat Pamukcu, Gary A. Piazza
  • Methods for identifying compounds for inhibition of neoplastic lesions, and pharmaceutical compositions containing such compounds
    Publication number: 20050244914
    Abstract: This invention provides pharmaceutical compositions containing compounds for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but prefereably not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia.
    Type: Application
    Filed: July 7, 2005
    Publication date: November 3, 2005
    Inventors: Li Liu, Bing Zhu, Han Li, W. Thompson, Rifat Pamukcu, Gary Piazza
  • Diagnostic methods for neoplasia
    Patent number: 6875575
    Abstract: This invention provides a method for diagnosing a patient with neoplasia.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: April 5, 2005
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Rifat Pamukcu, Gary A. Piazza
  • Method for treating a patient with neoplasia by treatment with a platinum coordination complex
    Patent number: 6869944
    Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic platinum coordination complex.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: March 22, 2005
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Rifat Pamukcu, Kerstin B. Menander
  • Methods for identifying compounds for inhibition of neoplastic lesions, and pharmacetical compositions containing such compounds
    Publication number: 20040009464
    Abstract: This invention provides pharmaceutical compositions containing compounds for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but prefereably not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia.
    Type: Application
    Filed: September 24, 2002
    Publication date: January 15, 2004
    Inventors: Li Liu, Bing Zhu, Han Li, W. Joseph Thompson, Rifat Pamukcu, Gary A. Piazza
  • Method for treating a patient with neoplasia by treatment with a gonadotropin releasing hormone analog
    Publication number: 20030220252
    Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with a gonadotropin-releasing hormone analog.
    Type: Application
    Filed: March 1, 2003
    Publication date: November 27, 2003
    Inventors: Rifat Pamukcu, Kerstin B. Menander, Hector Alila
  • Methods for identifying compounds for inhibition of neoplastic lesions, and pharmacetical compositions containing such compounds
    Publication number: 20030190686
    Abstract: This invention provides pharmaceutical compositions containing compounds for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but prefereably not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia.
    Type: Application
    Filed: September 24, 2002
    Publication date: October 9, 2003
    Inventors: Rifat Pamukcu, Gary A. Piazza
  • Packaged pharmaceuticals and methods for causing compounds and pharmaceutical compositions to be used as inhibitors of neoplastic lesions
    Publication number: 20030175833
    Abstract: This invention provides pharmaceutical compositions containing compounds for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but prefereably not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia.
    Type: Application
    Filed: September 20, 2002
    Publication date: September 18, 2003
    Inventors: Li Liu, Bing Zhu, Han Li, W. Joseph Thompson, Rifat Pamukcu, Gary A. Piazza
  • Substituted condensation products of N-benzyl-3-indenylacentamides with heterocyclic aldehydes for neoplasia
    Patent number: 6610854
    Abstract: Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes are useful for inducing or promoting apotosis and for arresting uncontrolled neoplastic cell proliferation, and are specifically useful in the arresting and treatment of neoplasias, including precancerous and cancerous lesions.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: August 26, 2003
    Assignees: Cell Pathways, Inc., University of Arizona
    Inventors: Gerhard J. Sperl, Paul Gross, Klaus Brendel, Gary A. Piazza, Rifat Pamukcu
  • Method for treating a patient with neoplasia by treatment with an anthracycline antibiotic
    Publication number: 20030130210
    Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an anthracycline antibiotic.
    Type: Application
    Filed: October 21, 2002
    Publication date: July 10, 2003
    Inventors: Rifat Pamukcu, Kerstin B. Menander
  • Method for treating a patient with neoplasia by treatment with a platinum coordination complex
    Publication number: 20030113382
    Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic platinum coordination complex.
    Type: Application
    Filed: August 27, 2002
    Publication date: June 19, 2003
    Inventors: Rifat Pamukcu, Kerstin B. Menander
  • Method of treating a patient having precancerous lesions with phenyl quinazolinone derivatives
    Patent number: 6562830
    Abstract: Derivatives of 2-phenyl quinazolinones are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.
    Type: Grant
    Filed: November 9, 1999
    Date of Patent: May 13, 2003
    Assignee: Cell Pathways, Inc.
    Inventors: Rifat Pamukcu, Gary A. Piazza
  • Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative
    Patent number: 6555547
    Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic vinca alkaloid derivative.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: April 29, 2003
    Assignee: Cell Pathways, Inc.
    Inventors: Rifat Pamukcu, Joseph M. Lobacki
  • Methods for treating a patient with neoplasia by administering cGMP-specific PDE-inhibiting compounds
    Publication number: 20030064421
    Abstract: This invention provides a method to identify compounds potentially useful for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia.
    Type: Application
    Filed: September 24, 2002
    Publication date: April 3, 2003
    Inventors: Rifat Pamukcu, Gary A. Piazza
  • Method for diagnosing neoplasia
    Publication number: 20030044861
    Abstract: This invention provides a method for diagnosing a patient with neoplasia.
    Type: Application
    Filed: April 22, 2002
    Publication date: March 6, 2003
    Inventors: Li Liu, Bing Zhu, Han Li, W. Joseph Thompson, Gary A. Piazza, Rifat Pamukcu