Patents by Inventor Samuel D. Larsen

Samuel D. Larsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and solvate of 2-methyl-thieno-benzodiazepine
    Patent number: 5703232
    Abstract: The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno?2,3-b!?1,5!benzodiazepine (olanzapine) and a process for making such lower alcohol solvates of olanzapine. The invention provides a method for using such solvates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: December 30, 1997
    Assignee: Eli Lilly and Company
    Inventors: Charles A. Bunnell, Terrence Michael Hotten, Samuel D. Larsen, David Edward Tupper
  • Solvate of olanzapine
    Patent number: 5637584
    Abstract: The invention provides a methylene chloride solvate of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine. The invention provides a method for using such solvate.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: June 10, 1997
    Assignees: Eli Lilly and Company, Lilly Industries Limited
    Inventor: Samuel D. Larsen
  • Process and solvate of 2-methyl-thieno-benzodiazepine
    Patent number: 5631250
    Abstract: The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine (olanzapine) and a process for making such lower alcohol solyates of olanzapine. The invention provides a method for using such solyates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: May 20, 1997
    Assignees: Eli Lilly and Company, Lilly Industries Limited
    Inventors: Charles A. Bunnell, Terrence M. Hotten, Samuel D. Larsen, David E. Tupper