Abstract: Provided is an orally disintegrating tablet comprising a bitter-tasting pharmaceutically active ingredient in the form of bepotastine or a pharmacologically acceptable salt thereof that enables the bitter taste thereof to be masked, has both superior oral cavity disintegration and adequate hardness, and can be produced with ordinary tablet production equipment.

Abstract: The present invention relates to a stable liquid preparation comprising a camptothecin derivative which is prepared by binding a compound of the formula [I]: wherein R1 is a substituted or unsubstituted lower alkyl group, X1 is a group of the formula: —NHR2 (R2 is a hydrogen atom or a lower alkyl group) or a hydroxy group and Alk is a straight or branched chain alkylene group optionally interrupted by an oxygen atom, and a polysaccharide having carboxyl groups via an amino acid or a peptide, or a pharmaceutically acceptable sat thereof, which is adjusted to pH 5-8, or a stable pharmaceutical composition produced by lyophilizing said liquid preparation.

Abstract: An aqueous ecabet sodium solution preparation which contains at a concentration of 1 w/v % or more (in conversion to ecabet sodium) of sulfodehydroabietic acid, or its salt•ion, wherein said solution is adjusted to pH in the range of 7-8.5 with at least one pH buffer selected from a salt of a polycarboxylic acid and a salt of a polyphoshoric acid, and an inorganic base. The preparation is stable, less irritant and is suitable for intestinal administration.

Abstract: A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and water-slightly permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.