Patents by Inventor Sonya Merrill
Sonya Merrill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110300217Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: ApplicationFiled: August 17, 2011Publication date: December 8, 2011Inventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynsid
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Publication number: 20100028389Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: ApplicationFiled: October 1, 2009Publication date: February 4, 2010Inventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
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Publication number: 20040234600Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: ApplicationFiled: July 2, 2004Publication date: November 25, 2004Inventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
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Publication number: 20010038856Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: ApplicationFiled: July 13, 2001Publication date: November 8, 2001Inventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
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Patent number: 6284274Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.Type: GrantFiled: March 3, 2000Date of Patent: September 4, 2001Assignee: Alza CorporationInventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson
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Patent number: 6077538Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.Type: GrantFiled: June 15, 1999Date of Patent: June 20, 2000Assignee: Alza CorporationInventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson
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Patent number: 5948787Abstract: An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are present optionally with a nonionic surfactant and with an osmotic composition comprising a carbonate or bicarbonate for delivering the opiate analgesic and non-opiate analgesic from a dosage form.Type: GrantFiled: February 28, 1997Date of Patent: September 7, 1999Assignee: Alza CorporationInventors: Sonya Merrill, Atul D. Ayer, Paul M. Hwang, Anthony L. Kuczynski, Nils W. Ahlgren, Deborah J. Johnson
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Patent number: 5914131Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: GrantFiled: September 22, 1997Date of Patent: June 22, 1999Assignee: ALZA CorporationInventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
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Patent number: 5866164Abstract: A composition of matter is disclosed and claimed comprising an opioid antagonist and a high molecular weight poly(alkylene) or a poly(carboxymethylcellulose). A dosage form is disclosed and claimed comprising the composition of matter for displacing an opioid analgesic from the dosage form.Type: GrantFiled: March 12, 1997Date of Patent: February 2, 1999Assignee: ALZA CorporationInventors: Anthony L. Kuczynski, Jerry D. Childers, Glen E. Barclay, Susan Rodriguez, Sonya Merrill
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Patent number: 5783213Abstract: The present invention relates to an improvement in an osmotic delivery device wherein the device comprises a semipermeable wall comprising cellulose acetate butyrate and surrounding an internal compartment containing a beneficial agent or medicament formulation, a fluid-activated expandable driving member, optionally a partition layer between the agent formulation and the driving member, and, optionally a density member, and exit means in the semipermeable wall; and wherein the improvement comprises the cellulose acetate butyrate component of the semipermeable wall having a differential scanning calorimetry ("DSC") profile wherein the main or primary DSC peak has a minimum temperature peak above 228.degree. C. and the secondary DSC peak area is equal to or less than about 30% of the total combined areas of the primary and secondary DSC peaks.Type: GrantFiled: March 6, 1997Date of Patent: July 21, 1998Assignee: ALZA CorporationInventors: David L. Rivera, Sonya Merrill, James B. Eckenhoff, Jeremy C. Wright, James L. Osborne
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Patent number: 5702725Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: GrantFiled: March 5, 1996Date of Patent: December 30, 1997Assignee: Alza CorporationInventors: Sonya Merrill, Atul Devdatt Ayer, Navjot Chadha, Anthony L. Kuczynski
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Patent number: 5667805Abstract: A composition comprising morphine; and a dosage form comprising morphine are disclosed for morphine therapy. A method of using the composition and the dosage form are disclosed and indicated for morphine therapy.Type: GrantFiled: October 4, 1996Date of Patent: September 16, 1997Assignee: Alza CorporationInventors: Sonya Merrill, Atul Devdatt Ayer, Paul Hwang, Anthony L. Kuczynski
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Patent number: 5609885Abstract: The present invention relates to an improvement in an osmotic delivery device wherein the device comprises a semipermeable wall comprising cellulose acetate butyrate and surrounding an internal compartment containing a beneficial agent or medicament formulation, a fluid-activated expandable driving member, optionally a partition layer between the agent formulation and the driving member, and, optionally a density member, and exit means in the semipermeable wall; and wherein the improvement comprises the cellulose acetate butyrate component of the semipermeable wall having a differential scanning calorimetry ("DSC") profile wherein the main or primary DSC peak has a minimum temperature peak above 228.degree. C. and the secondary DSC peak area is equal to or less than about 30% of the total combined areas of the primary and secondary DSC peaks.Type: GrantFiled: February 10, 1995Date of Patent: March 11, 1997Assignee: ALZA CorporationInventors: David L. Rivera, Sonya Merrill, James B. Eckenhoff, Jeremy C. Wright, James L. Osborne
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Patent number: 5607696Abstract: The present invention relates to an improvement in an osmotic delivery device wherein the device comprises a semipermeable wall comprising cellulose acetate butyrate and surrounding an internal compartment containing a beneficial agent or medicament formulation, a fluid-activated expandable driving member, optionally a partition layer between the agent formulation and the driving member, and, optionally a density member, and exit means in the semipermeable wall; and wherein the improvement comprises the cellulose acetate butyrate component of the semipermeable wall having a differential scanning calorimetry ("DSC") profile wherein the main or primary DSC peak has a minimum temperature peak above 228.degree. C. and the secondary DSC peak area is equal to or less than about 30% of the total combined areas of the primary and secondary DSC peaks.Type: GrantFiled: May 16, 1995Date of Patent: March 4, 1997Assignee: Alza CorporationInventors: David L. Rivera, Sonya Merrill, James B. Eckenhoff, Jeremy C. Wright, James L. Osborne
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Patent number: 5593695Abstract: A therapeutic tablet comprising morphine, poly(alkylene oxide) and poly(vinylpyrrolidone) encased by a composition comprising a cellulose polymer.Type: GrantFiled: May 24, 1995Date of Patent: January 14, 1997Assignee: ALZA CorporationInventors: Sonya Merrill, Atul D. Ayer, Paul Hwang, Anthony L. Kuczynski
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Patent number: 5529787Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.Type: GrantFiled: July 7, 1994Date of Patent: June 25, 1996Assignee: Alza CorporationInventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
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Patent number: 5460826Abstract: A bilayer comprising a morphine layer of morphine, poly(alkylene oxide) and poly(vinylpyrrolidone); and an expandable contacting layer of coated granules of a higher molecular weight poly(alkylene oxide) and a hydroxyalkylcellulose, which bilayer is disclosed for morphine therapy. A method is disclosed for using the bilayer composition.Type: GrantFiled: June 27, 1994Date of Patent: October 24, 1995Assignee: Alza CorporationInventors: Sonya Merrill, Atul D. Ayer, Paul Hwang, Anthony L. Kuczynski
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Patent number: 5318558Abstract: A drug delivery capsule from which the delivery of the drug is driven by the osmotic infusion of moisture by the capsule from a physiological environment is provided with a delivery orifice which opens intermittently to achieve a pulsatile delivery effect. The wall in which the orifice is formed is constructed of an elastic material, preferably an elastomer, which stretches under a pressure differential caused by the pressure rise inside the capsule as the osmotic infusion progresses. The orifice is small enough that when the elastic wall is relaxed, the flow rate of drug through the orifice is substantially zero, but that when the elastic wall is stretched due to the pressure differential across the wall exceeding a threshold, the orifice expands sufficiently to allow the release of the drug at a physiologically beneficial rate.Type: GrantFiled: December 1, 1992Date of Patent: June 7, 1994Assignee: ALZA CorporationInventors: Andreas Linkwitz, Judy A. Magruder, Sonya Merrill
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Patent number: 5221278Abstract: A drug delivery capsule from which the delivery of the drug is driven by the osmotic infusion of moisture by the capsule from a physiological environment is provided with a delivery orifice which opens intermittently to achieve a pulsatile delivery effect. The wall in which the orifice is formed is constructed of an elastic material, preferably an elastomer, which stretches under a pressure differential caused by the pressure rise inside the capsule as the osmotic infusion progresses. The orifice is small enough that when the elastic wall is relaxed, the flow rate of drug through the orifice is substantially zero, but that when the elastic wall is stretched due to the pressure differential across the wall exceeding a threshold, the orifice expands sufficiently to allow the release of the drug at a physiologically beneficial rate.Type: GrantFiled: March 12, 1992Date of Patent: June 22, 1993Assignee: Alza CorporationInventors: Andreas Linkwitz, Judy A. Magruder, Sonya Merrill