Patents by Inventor Stanley Wiegand

Stanley Wiegand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tie-2 ligands, methods of making and uses thereof
    Publication number: 20050175617
    Abstract: The invention provides for therapeutic compositions as well as a method of blocking blood vessel growth, a method of promoting neovascularization, a method of promoting the growth or differentiation of a cell expressing the TIE-2 receptor, a method of blocking the growth or differentiation of a cell expressing the TIE-2 receptor and a method of attenuating or preventing tumor growth in a human.
    Type: Application
    Filed: March 4, 2005
    Publication date: August 11, 2005
    Inventors: Stanley Wiegand, Peter Campochiaro, George Yancopoulos
  • Modified chimeric polypeptides with improved pharmacokinetic properties and methods of making and using thereof
    Publication number: 20050175610
    Abstract: Modified chimeric polypeptides with improved pharmacokinetics are disclosed useful for treating eye disorders, including age-related macular degeneration and diabetic retinopathy.
    Type: Application
    Filed: November 12, 2004
    Publication date: August 11, 2005
    Inventors: Stanley Wiegand, Nicholas Papadopoulos, George Yancopoulos
  • Method of treating corneal transplant rejection
    Publication number: 20050004027
    Abstract: Methods of preventing, reducing, or treating corneal transplant rejection to improve transplant survival in a subject in need thereof comprising administering an agent capable of blocking or inhibiting vascular endothelial growth factor (VEGF) are provided. The methods are useful for inhibiting or preventing corneal transplant rejection in a human subject who is the recipient of a transplanted cornea.
    Type: Application
    Filed: April 23, 2004
    Publication date: January 6, 2005
    Inventors: Stanley Wiegand, Jingtai Cao, Claus Cursiefen