Patents by Inventor Susan M. Bjorge

Susan M. Bjorge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloprotease inhibitors
    Patent number: 5939583
    Abstract: Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula ##STR1## in which T is a pharmaceutically-acceptable substituent group; A is CH.sub.2, CH, or N; G is CH.sub.2 or CH; and R.sup.1 is any of a variety of disclosed substituent groups. The class of compounds of the invention includes ring-containing materials in which the units A and G are joined. The compounds of the invention are mixtures of diastereomers, or individual diastereomers making up these mixtures.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: August 17, 1999
    Assignee: Bayer Corporation
    Inventors: Harold C. E. Kluender, Susan M. Bjorge, Lisa Marie Zadjura, William Frederick Brubaker
  • [(Hydroxyphenylamino) carbonyl] pyrroles
    Patent number: 5385929
    Abstract: 2-(4-Fluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[( hydroxyphenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, and their lactone forms, and salts and solyates thereof, inhibit cholesterol biosynthesis, and thus are useful in treating hypercholesterolemia.
    Type: Grant
    Filed: May 4, 1994
    Date of Patent: January 31, 1995
    Assignee: Warner-Lambert Company
    Inventors: Susan M. Bjorge, Ann E. Black, Bruce D. Roth, Thomas Woolf