Patents by Inventor Thomas R. Dean

Thomas R. Dean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds with 5-HTactivity useful for treating disorders of the outer retina
    Patent number: 7763619
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A agonist activity are disclosed.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: July 27, 2010
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Michael A. Kapin, Mark R. Hellberg, Thomas R. Dean
  • COMPOUNDS WITH 5-HT1A ACTIVITY USEFUL FOR TREATING DISORDERS OF THE OUTER RETINA
    Publication number: 20100168121
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A agonist activity are disclosed.
    Type: Application
    Filed: March 8, 2010
    Publication date: July 1, 2010
    Applicant: ALCON, INC.
    Inventors: Robert J. Collier, JR., Michael A. Kapin, Mark R. Hellberg, Thomas R. Dean
  • Tree securing device and associated methods
    Patent number: 7533489
    Abstract: A system for supporting lines of trees growing in pots includes poles supported in an upright position, with a first cable running between pairs of poles. Tree trunks are attached to the first cable with a device that includes a length of helical cable, a second cable, that is adapted for mating with the first cable, formed into a “V” shape. A pair of deformable cylinders, one having a longitudinal slit, are included. The slit cylinder is positionable over the first cable on a first side of the tree trunk. The second cylinder is threaded onto the second cable into a notch section thereof, and placed on a second side of the tree trunk. The two arms of the second cable are wound about the first cable on opposite sides of the tree trunk to prevent slippage therebetween, leaving at least one end free for ease of disconnect.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 19, 2009
    Assignee: Pierson Supply Company, Inc.
    Inventors: Delwood Nelson, Thomas R. Dean, David A. Monk, William Bartow Mercer
  • Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders
    Patent number: 7285553
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: October 23, 2007
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Hwang-Hsing Chen
  • Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders
    Patent number: 7060704
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: June 13, 2006
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Hwang-Hsing Chen
  • Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders
    Patent number: 6960579
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: November 1, 2005
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Hwang-Hsing Chen
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20040198817
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 7, 2004
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, George E. Barnes, Michael L. Chandler, Thomas R. Dean, Jesse A. May, Louis Desantis
  • Serotonergic 5ht2 agonists for treating glaucoma
    Patent number: 6664286
    Abstract: Compounds with 5HT2 receptor agonist activity useful for treating glaucoma, including lowering intraocular pressure. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: December 16, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Mark R. Hellberg
  • Compounds with 5-ht1a activity useful for treating disorders of the outer retina
    Publication number: 20030207890
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A against activity are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: November 6, 2003
    Inventors: Robert J Collier, Michael A Kapin, Mark R Hellberg, Thomas R Dean
  • Serotonergic 5HT2 agonists for treating glaucoma
    Publication number: 20030203912
    Abstract: Compounds with 5HT2 receptor agonist activity useful for treating glaucoma, including lowering intraocular pressure. Compositions and methods for their use are also disclosed.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 30, 2003
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Mark R. Hellberg
  • Compounds with 5-ht activity useful for controlling visual field loss
    Publication number: 20030119846
    Abstract: Compounds with 5-HT1A agonist activity which are useful for controlling the visual field loss associated with glaucoma are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 26, 2003
    Inventors: Robert J. Collier Jr, Mark R. Hellberg, Thomas R. Dean
  • Compounds with 5-ht2 and 5-ht1a agonist activity for treating glaucoma
    Publication number: 20030114512
    Abstract: Compounds with both 5-HT2 and 5-HT1A agonist activity which are useful for lowering and controlling IOP and the treatment of glaucomatous optic neuropathy.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 19, 2003
    Inventors: Robert J Collier, Thomas R Dean, Mark R Hellberg
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20020111381
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: February 5, 2002
    Publication date: August 15, 2002
    Inventors: Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6344478
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis, Jr.
  • Brinzolamide and brimonidine for treating glaucoma
    Patent number: 6316441
    Abstract: Methods and compositions for treating ocular conditions which find their etiology in compromised ocular blood flow with brinzolamide and brimonidine are disclosed.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: November 13, 2001
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Thomas R. Dean, Louis Desantis, Jr., Billie M. York
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20010023258
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: February 6, 2001
    Publication date: September 20, 2001
    Inventors: Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis
  • Use of brinzolamide to prevent visual field loss
    Patent number: 6242441
    Abstract: Methods for preventing or slowing visual field loss are disclosed.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: June 5, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Angela C. Kothe, Lewis H. Silver, Thomas R. Dean
  • Brinzolamide and brimonidine for treating ocular conditions
    Patent number: 6242442
    Abstract: Methods and compositions for treating ocular conditions which find their etiology in compromised ocular blood flow with brinzolamide and brimonidine are disclosed.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: June 5, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Louis Desantis, Jr., Billie M. York
  • Conformationally rigid aryl prostaglandins for use in glaucoma therapy
    Patent number: 6169111
    Abstract: Conformationally rigid aryl prostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic pharmaceutical compositions comprising said prostaglandins.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: January 2, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Paul W. Zinke, John E. Bishop, Thomas R. Dean, Mark R. Hellberg
  • Combinations of DP and FP type prostaglandins for lowering IOP
    Patent number: 6166073
    Abstract: Compositions containing DP-agonist and FP-agonists prostaglandin agonists and methods of their use in treating glaucoma or ocular hypertension are disclosed.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: December 26, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Mark Hellberg, Verney L. Sallee