Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.

Abstract: The invention provides a pharmaceutical composition which is a combination of an insulin-secretion stimulant and a HMG-CoA reductase inhibitor. Suitable insulin-secretion stimulants include the sulfonylurea drugs, and suitable HMG-CoA reductase inhibitors include the statin drugs. The composition may be formulated to provide extended-release characteristics of one or both of the active components. Also provided are methods for treating a diabetic patient using a combination of an insulin-secretion stimulant and a HMG-CoA reductase inhibitor. Practice of the methods of the invention may result in the administration of fewer dosages to the patient. The invention also provides a pharmaceutical composition which is a combination of an antihyperglycemic drug, particularly a biguanide compound, in combination with a HMG-CoA reductase inhibitor. Also provided are methods for treating a diabetic patient using a combination of an antihyperglycemic biguanide compound and a HMG-CoA reductase inhibitor.

Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.

Abstract: This invention provides a rectally administered composition for inhibiting epileptic seizure and to its methods of use. The composition contains, in a suitable solvent, an anti-epileptic agent for inhibiting epileptic seizure, a buffer for maintaining pH, and a thickener for imparting a viscosity to the composition effective for rectal administration by injection to a patient in epileptic seizure.