Patents by Inventor Tsutomu Tani
Tsutomu Tani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8092830Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.Type: GrantFiled: July 2, 2007Date of Patent: January 10, 2012Assignees: Wako Pure Chemical Industries, Ltd., Takeda Pharmaceutical Company LimitedInventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
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Publication number: 20070259036Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.Type: ApplicationFiled: July 2, 2007Publication date: November 8, 2007Inventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
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Publication number: 20060128938Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.Type: ApplicationFiled: February 7, 2006Publication date: June 15, 2006Inventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
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Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof
Patent number: 7049464Abstract: A process for producing an aminoalkylsulfonic acid of formula [2]: wherein R1 and R2 are each independently hydrogen, alkyl, aryl or aralkyl; and R3 and R4 are each independently hydrogen or alkyl, comprising reacting an aminoalkylsulfonate salt of formula [1]: wherein M is alkali metal, organic ammonium or ammonium ion; and R1 to R4 are as described above, an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon, carboxylic acids having 2 to 12 carbon and dimethylformamide, with an organic acid; and a method of salt exchange for an aminoalkylsulfonate salt of formula [1?]: wherein M? is alkali metal, organic ammonium or ammonium ion; and R1 and R4 are as described above, comprising reacting the aminoalkylsulfonate salt formula [2] with a hydroxide of formula [6]: M?OH[6] wherein M? is as described above, in alcohol or water.Type: GrantFiled: August 27, 2003Date of Patent: May 23, 2006Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Takuhiro Kimura, Tsutomu Tani, Reiji Miyahara -
Patent number: 7019106Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.Type: GrantFiled: August 6, 2001Date of Patent: March 28, 2006Assignees: Wako Pure Chemical Industries, Ltd., Takeda Pharmaceutical Company LimitedInventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
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Publication number: 20030153724Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.Type: ApplicationFiled: April 3, 2003Publication date: August 14, 2003Inventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
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Patent number: 5463075Abstract: Novel and improved simple process for preparing a 1,2-pyrazolidine-4-yl-disulfide compound represented by the following formula: ##STR1## wherein R.sup.1 and R.sup.2 are, independently each other, a hydrogen atom or an amino-protecting group.This compound may be prepared by reacting a compound of the formula: ##STR2## wherein R.sup.3 is an acid anion residue group, and R.sup.1 and R.sup.2 have the same meanings as above, with a disulfide compound selected from the group consisting of an alkali metal disulfide, an alkali earth metal disulfide, an ammonium disulfide and a tri-alkylammonium disulfide.Type: GrantFiled: September 6, 1994Date of Patent: October 31, 1995Assignee: WAKO Pure Chemical Industries, Ltd.Inventors: Motoshige Sumino, Tsutomu Tani, Atsunori Sano
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Patent number: 5095149Abstract: 4-Halogeno-2-alkoxyimino-3-oxo fatty acid can be produced by one-pot and one-step by reacting a halogenating agent with a 2-alkoxyimino-3-oxo fatty acid ester in an ether solvent or a mixed solvent of an ether solvent and an inert organic solvent such as carbon tetrachloride, benzene, toluene, etc.Type: GrantFiled: August 31, 1990Date of Patent: March 10, 1992Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Tsutomu Tani, Kazuo Maruhashi, Tsutomu Miyagawa
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Patent number: 4261206Abstract: A fault diagnostic device comprises vibrating means for vibrating a winding by feeding current having a predetermined frequency; detecting means for detecting physical value given in said winding by the vibration; and indicating means for indicating the result of the detection by said detecting means whereby a diagnosis of fault can be performed in high reliability.Type: GrantFiled: August 1, 1979Date of Patent: April 14, 1981Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Akemi Futakawa, Tokio Fukunaga, Tsutomu Tani
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Patent number: 3975653Abstract: A creeping discharge and partial discharge-prevention means for a stator coil end of a rotary electric machine is disclosed. It includes an grounding electrode on an insulator of the stator coil end of the rotary electric machine, a first electrical stress grading coated layer on the insulator of the coil end including the end of the grounding electrode, a shield insulator made of insulation material around the first electrical stress grading coated layer including the end of the grounding electrode, a shield electrode electrically connected to the grounding electrode around the shield insulator, and a second electrical stress grading coated layer coated on the shield insulator including the end of the shield electrode.Type: GrantFiled: March 13, 1975Date of Patent: August 17, 1976Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Takeshi Kawakami, Tsutomu Tani, Takatoshi Ishikawa, Syoji Hirabayashi